Information sur le laboratoire
Erwin Schurr (Ph.D.)
Scientifique séniorCentre de biologie translationnelle
Département de génétique humaine (McGill)
Profil de recherche
Mots-clés
Tuberculose • lèpre • traits complexes • transcriptomique • biologie des systèmesIntérêts de recherche
Ma recherche porte sur l'identification et l'évaluation de facteurs génétiques hôtes chez les cas de tuberculose et de lèpre. Nous travaillons sur ces maladies avec des groupes partenaires dans des pays endémiques et nous appliquons des concepts modernes de génétique, de génomique et de biologie des systèmes à nos analyse.Membre de l'équipe
| Nom | Poste |
|---|
Dernières publications
- Correa-Macedo, W., Dallmann-Sauer, M., Orlova, M., Manry, J., Fava, V. M., Huong, N. T., Ba, N. N., Van Thuc, N., Thai, V. H. & Schurr, E. (2024). Transcriptome immune-regulatory differences between leprosy patients and type 1 reaction patients, before onset of symptoms. PLoS neglected tropical diseases, vol. 18, p. e0011866.
- Moodley, S., Kroon, E., Naidoo, C. C., Nyawo, G. R., Wu, B. G., Naidoo, S., Chiyaka, T. L., Tshivhula, H., Singh, S., Li, Y., Warren, R. M., Hoal, E. G., Schurr, E., Clemente, J. C., Segal, L. N., Möller, M. & Theron, G. (2024). Latent Tuberculosis Infection Is Associated with an Enrichment of Short-Chain Fatty Acid-Producing Bacteria in the Stool of Women Living with HIV. Microorganisms, vol. 12.
- Alexandrova, Y., Yero, A., Olivenstein, R., Orlova, M., Schurr, E., Estaquier, J., Costiniuk, C. T. & Jenabian, M.-A. (2024). Dynamics of pulmonary mucosal cytotoxic CD8 T-cells in people living with HIV under suppressive antiretroviral therapy. Respiratory research, vol. 25, p. 240.
- Moodley, S., Kroon, E., Naidoo, C. C., Nyawo, G. R., Wu, B. G., Naidoo, S., Chiyaka, T. L., Tshivhula, H., Singh, S., Li, Y., Warren, R. M., Hoal, E. G., Schurr, E., Clemente, J., Segal, L. N., Möller, M. & Theron, G. (2024). Latent tuberculosis infection is associated with an enrichment of short chain fatty acid producing bacteria in the stool of women living with HIV. Research square.
- Kroon, E. E., Correa-Macedo, W., Evans, R., Seeger, A., Engelbrecht, L., Kriel, J. A., Loos, B., Okugbeni, N., Orlova, M., Cassart, P., Kinnear, C. J., Tromp, G. C., Möller, M., Wilkinson, R. J., Coussens, A. K., Schurr, E. & Hoal, E. G. (2023). Neutrophil extracellular trap formation and gene programs distinguish TST/IGRA sensitization outcomes among Mycobacterium tuberculosis exposed persons living with HIV. PLoS genetics, vol. 19, p. e1010888.
- Rivière, P., Le Chevillier, A., Rullier, A., Marty, M., Schurr, E., Lapuyade, B., Célerier, B., Fernandez, B., Bessissow, T., Treton, X., Uzzan, M., Poullenot, F., Berger, A., Zerbib, F. & Laharie, D. (2023). Deep ulcers are associated with increased C-reactive protein in active ulcerative colitis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, vol. 55, p. 1194-1200.
- Su, C.-Y., Zhou, S., Gonzalez-Kozlova, E., Butler-Laporte, G., Brunet-Ratnasingham, E., Nakanishi, T., Jeon, W., Morrison, D. R., Laurent, L., Afilalo, J., Afilalo, M., Henry, D., Chen, Y., Carrasco-Zanini, J., Farjoun, Y., Pietzner, M., Kimchi, N., Afrasiabi, Z., Rezk, N., Bouab, M., Petitjean, L., Guzman, C., Xue, X., Tselios, C., Vulesevic, B., Adeleye, O., Abdullah, T., Almamlouk, N., Moussa, Y., DeLuca, C., Duggan, N., Schurr, E., Brassard, N., Durand, M., Del Valle, D. M., Thompson, R., Cedillo, M. A., Schadt, E., Nie, K., Simons, N. W., Mouskas, K., Zaki, N., Patel, M., Xie, H., Harris, J., Marvin, R., Cheng, E., Tuballes, K., Argueta, K., Scott, I., Mount Sinai COVID-19 Biobank Team, Greenwood, C. M. T., Paterson, C., Hinterberg, M. A., Langenberg, C., Forgetta, V., Pineau, J., Mooser, V., Marron, T., Beckmann, N. D., Kim-Schulze, S., Charney, A. W., Gnjatic, S., Kaufmann, D. E., Merad, M. & Richards, J. B. (2023). Circulating proteins to predict COVID-19 severity. Scientific reports, vol. 13, p. 6236.
- Dallmann-Sauer, M., Xu, Y. Z., da Costa, A. L. F., Tao, S., Gomes, T. A., Prata, R. B. D. S., Correa-Macedo, W., Manry, J., Alcaïs, A., Abel, L., Cobat, A., Fava, V. M., Pinheiro, R. O., Lara, F. A., Probst, C. M., Mira, M. T. & Schurr, E. (2023). Allele-dependent interaction of LRRK2 and NOD2 in leprosy. PLoS pathogens, vol. 19, p. e1011260.
- Mendonca, L. E., Pernet, E., Khan, N., Sanz, J., Kaufmann, E., Downey, J., Grant, A., Orlova, M., Schurr, E., Krawczyk, C., Jones, R. G., Barreiro, L. B. & Divangahi, M. (2022). Human alveolar macrophage metabolism is compromised during Mycobacterium tuberculosis infection. Frontiers in immunology, vol. 13, p. 1044592.
- Butler-Laporte, G., Gonzalez-Kozlova, E., Su, C.-Y., Zhou, S., Nakanishi, T., Brunet-Ratnasingham, E., Morrison, D., Laurent, L., Aflalo, J., Aflalo, M., Henry, D., Chen, Y., Carrasco-Zanini, J., Farjoun, Y., Pietzner, M., Kimchi, N., Afrasiabi, Z., Rezk, N., Bouab, M., Petitjean, L., Guzman, C., Xue, X., Tselios, C., Vulesevic, B., Adeleye, O., Abdullah, T., Almamlouk, N., Moussa, Y., DeLuca, C., Duggan, N., Schurr, E., Brassard, N., Durand, M., Del Valle, D. M., Thompson, R., Cedillo, M. A., Schadt, E., Nie, K., Simons, N. W., Mouskas, K., Zaki, N., Patel, M., Xie, H., Harris, J., Marvin, R., Cheng, E., Tuballes, K., Argueta, K., Scott, I., Mount Sinai COVID-19 Biobank Team, Greenwood, C. M. T., Paterson, C., Hinterberg, M., Langenberg, C., Forgetta, V., Mooser, V., Marron, T., Beckmann, N. D., Kenigsberg, E., Charney, A. W., Kim-Schulze, S., Merad, M., Kaufmann, D. E., Gnjatic, S. & Richards, J. B. (2022). Correction: The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals. Clinical proteomics, vol. 19, p. 40.
Voir aussi
