Lab Information

Sapha Barkati (MD/MSc)

Associate Investigator
Clinical Research Unit
Department of Medicine (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 20%
 Epidemiology: 60%
 Evaluation: 20%
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Tropical medicine • travel medicine • migrant health • parasitology • neglected tropical diseases • epidemiology

Research Interests

My research focuses on measuring the burden and improving the care of parasitic diseases such as strongyloidiasis and tegumentary leishmaniasis in vulnerable populations, with a focus on migrants and immunocompromised individuals. I am currently conducting studies on Strongyloides knowledge and awareness among Canadian physicians to build educational tools that will improve Strongyloides screening in the high-risk population. I am also studying the prevalence of Strongyloides in the immunocompromised population in non-endemic countries and the best screening strategy in that population. In collaboration with Universidad Peruana Cayetano Heredia in Lima, Peru, I am studying the response to Strongyloides stercoralis treatment in the HTLV-1 population. I am also interested in the management of tegumentary leishmaniasis in travellers and migrants. One of the ultimate goals of my research is to increase knowledge and awareness of neglected tropical diseases such as strongyloidiasis and tegumentary leishmaniasis among physicians in non-endemic countries. Another is to determine the most cost-effective strategies for Strongyloides screening in the high-risk population and the best treatment in the immunocompromised population and HTLV-1 co-infected, to inform evidence-based preventive clinical care and management guidelines.

Team Members

Name Position

Latest Publications

  1. Skowronski, D. M., Febriani, Y., Ouakki, M., Setayeshgar, S., El Adam, S., Zou, M., Talbot, D., Prystajecky, N., Tyson, J. R., Gilca, R., Brousseau, N., Deceuninck, G., Galanis, E., Fjell, C. D., Sbihi, H., Fortin, E., Barkati, S., Sauvageau, C., Naus, M., Patrick, D. M., Henry, B., Hoang, L. M. N., De Wals, P., Garenc, C., Carignan, A., Drolet, M., Jassem, A. N., Sadarangani, M., Brisson, M., Krajden, M. & De Serres, G. (2022). Two-dose SARS-CoV-2 vaccine effectiveness with mixed schedules and extended dosing intervals: test-negative design studies from British Columbia and Quebec, Canada. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
  2. Passos-Castilho, A. M., Labbé, A.-C., Barkati, S., Luong, M.-L., Dagher, O., Maynard, N., Tutt-Guérette, M.-A., Kierans, J., Rousseau, C., Benedetti, A., Azoulay, L. & Greenaway, C. (2022). Outcomes of hospitalized COVID-19 in Canada: impact of ethnicity, migration status, and country of birth ethnicity, migration and COVID-19 in-hospital outcomes in Canada. Journal of travel medicine.
  3. Alghounaim, M., Chivinski, J. & Barkati, S. (2022). Cutaneous leishmaniasis in a 12-year-old Syrian immigrant. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, vol. 194, p. E93-E94.
  4. Barkati, S., Greenaway, C. & Libman, M. D. (2022). Strongyloidiasis in immunocompromised migrants to non-endemic countries in the era of COVID-19: What is the role for presumptive ivermectin?. Journal of travel medicine, vol. 29.
  5. Carazo, S., Talbot, D., Boulianne, N., Brisson, M., Gilca, R., Deceuninck, G., Brousseau, N., Drolet, M., Ouakki, M., Sauvageau, C., Barkati, S., Fortin, É., Carignan, A., De Wals, P., Skowronski, D. M. & De Serres, G. (2021). Single-dose mRNA vaccine effectiveness against SARS-CoV-2 in healthcare workers extending 16 weeks post-vaccination: a test-negative design from Quebec, Canada. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
  6. Barkati, S. & Libman, M. D. (2021). Cutaneous leishmaniasis and the vicious cycle of neglect. Journal of travel medicine, vol. 28.
  7. Naeem, F., Nathan, K., Chivinski, J., Ekmekjian, T., Libman, M. & Barkati, S. (2021). Intravenous liposomal amphotericin B efficacy and safety for cutaneous and mucosal leishmaniasis: a systematic review and meta-analysis protocol. BMJ open, vol. 11, p. e045707.
  8. Greenaway, C., Hargreaves, S., Barkati, S., Coyle, C. M., Gobbi, F., Veizis, A. & Douglas, P. (2020). COVID-19: Exposing and addressing health disparities among ethnic minorities and migrants. Journal of travel medicine, vol. 27.
  9. Lawandi, A., Yansouni, C. P., Libman, M., Rubin, E., Emil, S., Bernard, C., Ndao, M. & Barkati, S. (2019). A 9-Year-Old Female With a Cough and Cavitary Lung Lesion. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 69, p. 705-708.
  10. Grandjean Lapierre, S., Barkati, S., Desjardins, M., Ndao, M., Libman, M., Poirier, L., Mottard, S., Désy, D. & Dufresne, S.-F. (2020). Isolated muscular cystic echinococcosis mimicking neoplasia. Journal of travel medicine, vol. 27.
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