Lab Information
Sapha Barkati (MD/MSc)
InvestigatorClinical Research Unit
Department of Medicine (McGill)
Research Profile
http://www.mcgill.ca/tropmed/
Keywords
Tropical medicine • travel medicine • migrant health • parasitology • neglected tropical diseases • epidemiologyResearch Interests
My research focuses on measuring the burden and improving the care of parasitic diseases such as strongyloidiasis and tegumentary leishmaniasis in vulnerable populations, with a focus on migrants and immunocompromised individuals. I am currently conducting studies on Strongyloides knowledge and awareness among Canadian physicians to build educational tools that will improve Strongyloides screening in the high-risk population. I am also studying the prevalence of Strongyloides in the immunocompromised population in non-endemic countries and the best screening strategy in that population. In collaboration with Universidad Peruana Cayetano Heredia in Lima, Peru, I am studying the response to Strongyloides stercoralis treatment in the HTLV-1 population. I am also interested in the management of tegumentary leishmaniasis in travellers and migrants. One of the ultimate goals of my research is to increase knowledge and awareness of neglected tropical diseases such as strongyloidiasis and tegumentary leishmaniasis among physicians in non-endemic countries. Another is to determine the most cost-effective strategies for Strongyloides screening in the high-risk population and the best treatment in the immunocompromised population and HTLV-1 co-infected, to inform evidence-based preventive clinical care and management guidelines.Team Members
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Latest Publications
- Dagher, O., Passos-Castilho, A. M., Sareen, V., Labbé, A.-C., Barkati, S., Luong, M.-L., Rousseau, C., Benedetti, A., Azoulay, L. & Greenaway, C. (2024). Impact of Language Barriers on Outcomes and Experience of COVID-19 Patients Hospitalized in Quebec, Canada, During the First Wave of the Pandemic. Journal of immigrant and minority health, vol. 26, p. 3-14.
- Chivinski, J., Nathan, K., Naeem, F., Ekmekjian, T., Libman, M. D. & Barkati, S. (2023). Intravenous Liposomal Amphotericin B Efficacy and Safety for Cutaneous and Mucosal Leishmaniasis: A Systematic Review and Meta-analysis. Open forum infectious diseases, vol. 10, p. ofad348.
- Huits, R., Angelo, K. M., Amatya, B., Barkati, S., Barnett, E. D., Bottieau, E., Emetulu, H., Epelboin, L., Eperon, G., Medebb, L., Gobbi, F., Grobusch, M. P., Itani, O., Jordan, S., Kelly, P., Leder, K., Díaz-Menéndez, M., Okumura, N., Rizwan, A., Rothe, C., Saio, M., Waggoner, J., Yoshimura, Y., Libman, M., Hamer, D. H. & Schwartz, E. (2023). Clinical Characteristics and Outcomes Among Travelers With Severe Dengue : A GeoSentinel Analysis. Annals of internal medicine, vol. 176, p. 940-948.
- Barkati, S., Greenaway, C. & Libman, M. (2023). Strongyloidiasis-related lung involvement: too much of a bad thing. Current opinion in infectious diseases, vol. 36, p. 203-208.
- Díaz-Menéndez, M., Angelo, K. M., de Miguel Buckley, R., Bottieau, E., Huits, R., Grobusch, M. P., Gobbi, F. G., Asgeirsson, H., Duvignaud, A., Norman, F. F., Javelle, E., Epelboin, L., Rothe, C., Chappuis, F., Martinez, G. E., Popescu, C., Camprubí-Ferrer, D., Molina, I., Odolini, S., Barkati, S., Kuhn, S., Vaughan, S., McCarthy, A., Lago, M., Libman, M. D. & Hamer, D. H. (2023). Dengue outbreak amongst travellers returning from Cuba-GeoSentinel surveillance network, January-September 2022. Journal of travel medicine, vol. 30.
- Harrison, L. B., Bergeron, G., Cadieux, G., Charest, H., Fafard, J., Levade, I., Blais, A. C., Huchet, E., Trottier, B., Vlad, D., Szabo, J., Thomas, R., Poulin, S., Greenaway, C., Zaharatos, G. J., Oughton, M., Chakravarti, A., Pilarski, R., Bui-Nguyen, A., Benomar, K., Libman, M. D., Vinh, D. C., Duggan, A. T., Graham, M., Klein, M. B. & Barkati, S. (2023). Monkeypox in Montréal: Epidemiology, Phylogenomics, and Public Health Response to a Large North American Outbreak. Annals of internal medicine, vol. 176, p. 67-76.
- Barkati, S. & Harrison, L. B. (2022). Monkeypox outbreak 2022: "See one, do one, teach one" no longer the rule. Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada, vol. 7, p. 157-158.
- Carazo, S., Skowronski, D. M., Brisson, M., Sauvageau, C., Brousseau, N., Gilca, R., Ouakki, M., Barkati, S., Fafard, J., Talbot, D., Gilca, V., Deceuninck, G., Garenc, C., Carignan, A., De Wals, P. & De Serres, G. (2022). Estimated Protection of Prior SARS-CoV-2 Infection Against Reinfection With the Omicron Variant Among Messenger RNA-Vaccinated and Nonvaccinated Individuals in Quebec, Canada. JAMA network open, vol. 5, p. e2236670.
- Angelo, K. M., Smith, T., Camprubí-Ferrer, D., Balerdi-Sarasola, L., Díaz Menéndez, M., Servera-Negre, G., Barkati, S., Duvignaud, A., Huber, K. L. B., Chakravarti, A., Bottieau, E., Greenaway, C., Grobusch, M. P., Mendes Pedro, D., Asgeirsson, H., Popescu, C. P., Martin, C., Licitra, C., de Frey, A., Schwartz, E., Beadsworth, M., Lloveras, S., Larsen, C. S., Guagliardo, S. A. J., Whitehill, F., Huits, R., Hamer, D. H., Kozarsky, P., Libman, M. & GeoSentinel Network Collaborators (2023). Epidemiological and clinical characteristics of patients with monkeypox in the GeoSentinel Network: a cross-sectional study. The Lancet. Infectious diseases, vol. 23, p. 196-206.
- Carazo, S., Skowronski, D. M., Brisson, M., Barkati, S., Sauvageau, C., Brousseau, N., Gilca, R., Fafard, J., Talbot, D., Ouakki, M., Gilca, V., Carignan, A., Deceuninck, G., De Wals, P. & De Serres, G. (2023). Protection against omicron (B.1.1.529) BA.2 reinfection conferred by primary omicron BA.1 or pre-omicron SARS-CoV-2 infection among health-care workers with and without mRNA vaccination: a test-negative case-control study. The Lancet. Infectious diseases, vol. 23, p. 45-55.
See also
