Lab Information
Cédric Yansouni (MD)
ScientistCentre for Translational Biology
Department of Medicine (McGill)
Research Profile
http://www.mcgill.ca/tropmed/
Keywords
Diagnostics • antimicrobial resistance • low resource and remote settings • circumpolar health • clinical tropical medicineResearch Interests
My research is focused on improving diagnostic tools and care for infectious diseases in remote and low resource settings (LRS), including in Northern Indigenous communities in Canada. This is done through the development and field validation of diagnostics, implementation research, and translation to the regulatory and policy level as technical adviser, for instance, to the World Health Organization, Health Canada, the Committee to Advise on Tropical Medicine and Travel (CATMAT), the Institut national d’excellence en santé et en services sociaux (INESSS), and product development partnerships. In addition, a core activity of my group involves optimizing current diagnostic laboratory approaches and innovating clinical bacteriology diagnostics for low-resource settings, aiming to contain the spread of antimicrobial resistance.Team Members
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Latest Publications
- Reszetnik, G., Hammond, K., Mahshid, S., AbdElFatah, T., Nguyen, D., Corsini, R., Caya, C., Papenburg, J., Cheng, M. P. & Yansouni, C. P. (2024). Next-generation rapid phenotypic antimicrobial susceptibility testing. Nature communications, vol. 15, p. 9719.
- Ducrocq, J., Lévesque, B., De Serres, G., Boiteau, V., Yansouni, C. P., Proulx, J.-F. & Talbot, D. (2024). Increasing our knowledge about the epidemiology of Helicobacter pylori in Nunavik's Inuit population (Québec, Canada) using Qanuilirpitaa? 2017 cross-sectional survey. International journal of circumpolar health, vol. 83, p. 2398864.
- Xia, Y., Caya, C., Morin, V., Singh, A. E., Serhir, B., Libman, M., Goldfarb, D. M., Wong, T., Xiu, F., Bélanger, R., Touchette, J.-S., Yansouni, C. P. & Maheu-Giroux, M. (2024). The population-level impact of introducing rapid diagnostic tests on syphilis transmission in Canadian arctic communities - a mathematical modeling study. Lancet regional health. Americas, vol. 37, p. 100845.
- Caya, C., Menzies, D., Papenburg, J., Yansouni, C. & Campbell, J. (2024). Characteristics associated with SARS-CoV-2 testing, infection and vaccine uptake among essential non-healthcare workers in Montréal, 2021. Canada communicable disease report = Releve des maladies transmissibles au Canada, vol. 50, p. 223-232.
- Camirand Lemyre, F., Honfo, S. H., Caya, C., Cheng, M. P., Colwill, K., Corsini, R., Gingras, A.-C., Jassem, A., Krajden, M., Márquez, A. C., Mazer, B. D., McLennan, M., Renaud, C., Yansouni, C. P., Papenburg, J. & Lewin, A. (2023). Two-phase Bayesian latent class analysis to assess diagnostic test performance in the absence of a gold standard: COVID-19 serological assays as a proof of concept. Vox sanguinis, vol. 118, p. 1069-1077.
- Cheng, M. P., Paquette, K., Lawandi, A., Stabler, S. N., Akhter, M., Davidson, A. C., Gavric, M., Jinah, R., Saeed, Z., Demir, K., Sangsari, S., Huang, K., Mahpour, A., Shamatutu, C., Caya, C., Troquet, J.-M., Clark, G., Rush, B., Wong, T., Stenstrom, R., Sweet, D. & Yansouni, C. P. (2022). qSOFA does not predict bacteremia in patients with severe manifestations of sepsis. Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada, vol. 7, p. 364-368.
- Caya, C., Singh, A. E., Serhir, B., Morin, V., Libman, M. D., Corsini, R., Goldfarb, D. M., Wong, T., Xia, Y., Maheu-Giroux, M. & Yansouni, C. P. (2023). Rapid diagnostic testing for syphilis in Arctic communities (the STAR study): A multisite prospective field diagnostic accuracy study in an intended-use setting. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, vol. 29, p. 1335.e1-1335.e7.
- van Griensven, J., Diro, E. & Yansouni, C. P. (2023). Hidden sources of bias in diagnostic studies: the example of visceral leishmaniasis in east Africa. The Lancet. Infectious diseases, vol. 23, p. e108-e114.
- Lau, V. I., Fowler, R., Pinto, R., Tremblay, A., Borgia, S., Carrier, F. M., Cheng, M. P., Conly, J., Costiniuk, C. T., Daley, P., Duan, E., Durand, M., Fontela, P. S., Farjou, G., Fralick, M., Geagea, A., Grant, J., Keynan, Y., Khwaja, K., Lee, N., Lee, T. C., Lim, R., O'Neil, C. R., Papenburg, J., Semret, M., Silverman, M., Sligl, W., Somayaji, R., Tan, D. H. S., Tsang, J. L. Y., Weatherald, J., Yansouni, C. P., Zarychanski, R., Murthy, S. & E-CATCO authors, AMMI Clinical Research Network and Canadian Critical Care Trials Group (2022). Cost-effectiveness of remdesivir plus usual care versus usual care alone for hospitalized patients with COVID-19: an economic evaluation as part of the Canadian Treatments for COVID-19 (CATCO) randomized clinical trial. CMAJ open, vol. 10, p. E807-E817.
- Caya, C., Maheu-Giroux, M., Xia, Y., Serhir, B., Morin, V., Libman, M., Corsini, R., Goldfarb, D. M., Wong, T., Singh, A. E. & Yansouni, C. P. (2022). Stopping syphilis transmission in Arctic communities through rapid diagnostic testing: The STAR study protocol. PloS one, vol. 17, p. e0273713.
See also
