Lab Information
Marie-Josée Brouillette (MD)
ScientistCentre for Outcomes Research and Evaluation
Department of Psychiatry (McGill)
Research Profile
Keywords
HIV • post-COVIDResearch Interests
My research focuses on the psychosocial aspects of two medical conditions, HIV infection and the post-COVID syndrome. These studies are concerned with regulation of cognition and mood and understanding of their impact on everyday function and quality of life. The HIV study involves characterizing 900 HIV+ individuals across Canada, followed since 2013 to elucidate factors that contribute to the development of cognitive decline and mood changes, with interventional trials being conducted in selected subgroups of individuals. This study involves interdisciplinary collaborations (neurology, neuropsychology, epidemiology, HIV clinicians and community groups) and aims to develop innovative solutions that can be applied in the clinic. The study in post-COVID syndrome aims to characterize the profiles of symptoms experienced by people with “long COVID,” documenting the evolution of these symptoms over time and their impact on function. As part of the study, we offer self-management resources to address some of the problematic symptoms.Team Members
| Name | Position |
|---|
Latest Publications
- Matout, M., Brouillette, M.-J., Fellows, L. K. & Mayo, N. E. (2024). Using network analysis to provide evidence for brain health as a unified construct relevant to aging with HIV. Social psychiatry and psychiatric epidemiology.
- Michael, H. U., Brouillette, M.-J., Tamblyn, R., Fellows, L. K. & Mayo, N. E. (2024). Disentangling the Effects of Comorbidity and Polypharmacy on Cognitive Function and Physical Frailty in Individuals with HIV. Journal of acquired immune deficiency syndromes (1999).
- Chawla, S., Kaida, A., Brouillette, M.-J., Kleiner, B., Dubuc, D., Skerritt, L., Burchell, A. N., Rouleau, D., Loutfy, M., de Pokomandy, A. & CHIWOS research team (2024). Mental health service use and shortages among a cohort of women living with HIV in Canada. BMC health services research, vol. 24, p. 923.
- Mayo, N. E., Hum, S., Matout, M., Fellows, L. K. & Brouillette, M.-J. (2024). Portrait of mental health identified by people with the post-covid syndrome. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, vol. 33, p. 2509-2516.
- Michael, H. U., Brouillette, M.-J., Tamblyn, R., Fellows, L. K. & Mayo, N. E. (2024). Cognitive impact of anticholinergic and sedative burden in people living with HIV. AIDS (London, England), vol. 38, p. 1819-1828.
- Inceer, M., Boehnke, J., Brouillette, M.-J., Fellows, L. K. & Mayo, N. E. (2024). In Support of Multidimensional Frailty: A Structural Equation Model from the Canadian Positive Brain Health Now Cohort. AIDS research and human retroviruses.
- Michael, H. U., Brouillette, M.-J., Fellows, L. K. & Mayo, N. E. (2024). Medication Utilization Patterns in Patients with Post-COVID Syndrome (PCS): Implications for Polypharmacy and Drug-Drug Interactions. Journal of the American Pharmacists Association : JAPhA, p. 102083.
- Guay, É., Brouillette, M.-J., Drury, J., Garel, N. & Greenway, K. (2024). Rapid Improvement of Post-Partum Depression With Subanesthetic Racemic Ketamine. Journal of clinical psychopharmacology, vol. 44, p. 196-198.
- Michael, H. U., Brouillette, M.-J., Tamblyn, R., Fellows, L. K. & Mayo, N. E. (2024). The Association between anticholinergic/sedative burden and physical frailty in people aging with HIV. AIDS (London, England), vol. 38, p. 509-519.
- Michael, H. U., Enechukwu, O., Brouillette, M.-J., Tamblyn, R., Fellows, L. K. & Mayo, N. E. (2023). The Prognostic Utility of Anticholinergic Burden Scales: An Integrative Review and Gap Analysis. Drugs & aging, vol. 40, p. 763-783.
See also
