Lab Information
Jean-Pierre Routy (MD)
Senior ScientistCentre for Translational Biology
Department of Medicine (McGill)
Research Profile
Keywords
HIV • chronic viral infections • CMV • HHV8 • HIV reservoirs • gutResearch Interests
My research focuses on human immunodeficiency virus (HIV) pathogenesis aiming at finding an HIV cure. Improving knowledge in immune tolerance in cancer and immunometabolism will be key to developing strategy to conquer cancers and auto-immune diseases.Team Members
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Latest Publications
- Long, C., Cinque, F., Kablawi, D., Kim, D. H. D., Tadjo, T. F., Elgretli, W., Ballesteros, L. R., Lupu, A., Nudo, M., Lebouché, B., Kronfli, N., Cox, J., Costiniuk, C. T., De Pokomandy, A., Routy, J.-P., Klein, M. B., Lamonde, F., Agnihotram, R. V., Saeed, S. & Sebastiani, G. (2024). Material deprivation is associated with liver stiffness and liver-related outcomes in people with HIV. Liver international : official journal of the International Association for the Study of the Liver.
- Dias, J., Cattin, A., Bendoumou, M., Dutilleul, A., Lodge, R., Goulet, J.-P., Fert, A., Raymond Marchand, L., Wiche Salinas, T. R., Ngassaki Yoka, C.-D., Gabriel, E. M., Caballero, R. E., Routy, J.-P., Cohen, É. A., Van Lint, C. & Ancuta, P. (2024). Retinoic acid enhances HIV-1 reverse transcription and transcription in macrophages via mTOR-modulated mechanisms. Cell reports, vol. 43, p. 114414.
- Arora, A. K., Vicente, S., Engler, K., Lessard, D., Huerta, E., Ishak, J., Kronfli, N., Routy, J.-P., Cox, J., Lemire, B., Klein, M., de Pokomandy, A., Del Balso, L., Sebastiani, G., Vedel, I., Quesnel-Vallée, A., Lebouché, B. & ASAP Migrant Advisory Committee (2024). Patient-reported outcomes and experiences of migrants enrolled in a multidisciplinary HIV clinic with rapid, free, and onsite treatment dispensation: the 'ASAP' study. AIDS research and therapy, vol. 21, p. 40.
- Costiniuk, C. T., Lee, T., Singer, J., Galipeau, Y., Arnold, C., Langlois, M.-A., Needham, J., Jenabian, M.-A., Burchell, A. N., Samji, H., Chambers, C., Walmsley, S., Ostrowski, M., Kovacs, C., Tan, D. H. S., Harris, M., Hull, M., Brumme, Z. L., Lapointe, H. R., Brockman, M. A., Margolese, S., Mandarino, E., Samarani, S., Lebouché, B., Angel, J. B., Routy, J.-P., Cooper, C. L., Anis, A. H. & COVAXHIV Study Group (2024). Correlates of Breakthrough SARS-CoV-2 Infections in People with HIV: Results from the CIHR CTN 328 Study. Vaccines, vol. 12.
- Long, C., Al-Abdulmalek, A., Lai, J., Haegert, D. G., Isnard, S., Cournoyer, D. & Routy, J.-P. (2024). Haemophagocytic Lymphohistiocytosis Following the anti-PD-1 Nivolumab in a Patient with Gastric Cancer and Ankylosing Spondylitis. European journal of case reports in internal medicine, vol. 11, p. 004370.
- Bu, S., Royston, L., Mabanga, T., Berini, C. A., Tremblay, C., Lebouché, B., Cox, J., Costiniuk, C. T., Durand, M., Isnard, S. & Routy, J.-P. (2024). Proteomics validate circulating GDF-15 as an independent biomarker for COVID-19 severity. Frontiers in immunology, vol. 15, p. 1377126.
- Mehraj, V., Chen, J. & Routy, J.-P. (2024). Effects of statins beyond lipid-lowering agents in ART-treated HIV infection. Frontiers in immunology, vol. 15, p. 1339338.
- Fert, A., Richard, J., Marchand, L. R., Planas, D., Routy, J.-P., Chomont, N., Finzi, A. & Ancuta, P. (2024). Metformin Enhances Antibody-Mediated Recognition of HIV-Infected CD4+ T-Cells by Decreasing Viral Release. bioRxiv : the preprint server for biology.
- De Wit, S., Bonnet, F., Osiyemi, O., Bisshop, F., Olalla, J., Routy, J.-P., Wyen, C., Moodley, R., Pappa, K., Wang, R., Oyee, J., Saggu, P., Letang, E., Wynne, B., Jones, B., Smith, K. Y. & Ait-Khaled, M. (2024). Durable Efficacy of Switching From a 3- or 4-Drug Tenofovir Alafenamide-Based Regimen to the 2-Drug Regimen Dolutegravir/Lamivudine in the TANGO Study Through Week 196. Journal of acquired immune deficiency syndromes (1999).
- Anand, A., Vialard, F., Esmail, A., Ahmad Khan, F., O'Byrne, P., Routy, J.-P., Dheda, K. & Pant Pai, N. (2024). Self-tests for COVID-19: What is the evidence? A living systematic review and meta-analysis (2020-2023). PLOS global public health, vol. 4, p. e0002336.
See also
