Lab Information

Jean-Pierre Routy (MD)

Senior Scientist
Centre for Translational Biology
Department of Medicine (McGill)

Research Profile

 Fundamental: 50%
 Clinical: 50%
 Epidemiology: 0%
 Evaluation: 0%
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HIV • vaccine • lymphoma • T cells • cytokines

Research Interests

My research focuses on HIV pathogenesis aiming at finding an HIV cure. Improving knowledge in immune tolerance in cancer and in immune privileged sites (central nervous system, testis) will be key to develop strategy to conquer cancers and auto-immune diseases.

Team Members

Name Position

Latest Publications

  1. Karellis, A., Naeem, F., Nair, S., Mallya, S. D., Routy, J.-P., Gahagan, J., Yansouni, C. P., Kim, J. & Pai, N. P. (2022). Multiplexed rapid technologies for sexually transmitted infections: a systematic review. The Lancet. Microbe, vol. 3, p. e303-e315.
  2. Isnard, S., Royston, L., Lin, J., Fombuena, B., Bu, S., Kant, S., Mabanga, T., Berini, C., El-Far, M., Durand, M., Tremblay, C. L., Bernard, N. F., Kroemer, G. & Routy, J.-P. (2022). Distinct Plasma Concentrations of Acyl-CoA-Binding Protein (ACBP) in HIV Progressors and Elite Controllers. Viruses, vol. 14.
  3. Ahmed, D. S., Isnard, S., Berini, C., Lin, J., Routy, J.-P. & Royston, L. (2022). Coping With Stress: The Mitokine GDF-15 as a Biomarker of COVID-19 Severity. Frontiers in immunology, vol. 13, p. 820350.
  4. Chu, D., Lessard, D., Laymouna, M. A., Engler, K., Schuster, T., Ma, Y., Kronfli, N., Routy, J.-P., Hijal, T., Lacombe, K., Sheehan, N., Rougier, H. & Lebouché, B. (2022). Understanding the Risks and Benefits of a Patient Portal Configured for HIV Care: Patient and Healthcare Professional Perspectives. Journal of personalized medicine, vol. 12.
  5. Renault, C., Veyrenche, N., Mennechet, F., Bedin, A.-S., Routy, J.-P., Van de Perre, P., Reynes, J. & Tuaillon, E. (2022). Th17 CD4+ T-Cell as a Preferential Target for HIV Reservoirs. Frontiers in immunology, vol. 13, p. 822576.
  6. Almomen, A., Cox, J., Lebouche, B., Cheng, M., Frenette, C., Routy, J.-P. & Costiniuk, C. T. (2022). Ongoing impact of the social determinants of health during the second and third waves of the COVID-19 pandemic in People Living with HIV receiving care in a Montreal-based Tertiary Care Centre. AIDS research and human retroviruses, vol. 38, p. 359-362.
  7. Valantin, M.-A., Royston, L., Hentzien, M., Jary, A., Makinson, A., Veyri, M., Ronot-Bregigeon, S., Isnard, S., Palich, R. & Routy, J.-P. (2022). Therapeutic Perspectives in the Systemic Treatment of Kaposi's Sarcoma. Cancers, vol. 14.
  8. Routy, J.-P. & Isnard, S. (2022). Never say "never the twain shall meet": Combining antiretroviral therapy and RNA vaccine to obtain an adequate humoral immune response in people living with HIV. The Lancet regional health. Europe, vol. 13, p. 100310.
  9. Osiyemi, O., De Wit, S., Ajana, F., Bisshop, F., Portilla, J., Routy, J.-P., Wyen, C., Ait-Khaled, M., Leone, P., Pappa, K. A., Wang, R., Wright, J., George, N., Wynne, B., Aboud, M., van Wyk, J. & Smith, K. Y. (2022). Efficacy and Safety of Switching to Dolutegravir/Lamivudine (DTG/3TC) Versus Continuing a Tenofovir Alafenamide-Based 3- or 4-Drug Regimen for Maintenance of Virologic Suppression in Adults Living With HIV-1: Results Through Week 144 From the Phase 3, Non-inferiority TANGO Randomized Trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
  10. Isnard, S., Fombuena, B., Ouyang, J., Royston, L., Lin, J., Bu, S., Sheehan, N., Lakatos, P. L., Bessissow, T., Chomont, N., Klein, M., Lebouché, B., Costiniuk, C. T., Routy, B., Marette, A., Routy, J.-P. & Camu Camu Study Group (2022). Camu Camu effects on microbial translocation and systemic immune activation in ART-treated people living with HIV: protocol of the single-arm non-randomised Camu Camu prebiotic pilot study (CIHR/CTN PT032). BMJ open, vol. 12, p. e053081.
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