Lab Information

Jean-Pierre Routy (MD)

Senior Scientist
Centre for Translational Biology
Department of Medicine (McGill)

Research Profile

 Fundamental: 50%
 Clinical: 50%
 Epidemiology: 0%
 Evaluation: 0%
 This email address is being protected from spambots. You need JavaScript enabled to view it.


HIV • vaccine • lymphoma • T cells • cytokines

Research Interests

My research focuses on HIV pathogenesis aiming at finding an HIV cure. Improving knowledge in immune tolerance in cancer and in immune privileged sites (central nervous system, testis) will be key to develop strategy to conquer cancers and auto-immune diseases.

Team Members

Name Position

Latest Publications

  1. Sebastiani, G., Paisible, N., Costiniuk, C., Cox, J., Kablawi, D., Klein, M. B., Kronfli, N., Routy, J.-P., Falutz, J., Lebouché, B. & Guaraldi, G. (2022). The Relationship between Visceral Adiposity and Nonalcoholic Fatty Liver Disease Diagnosed by Controlled Attenuation Parameter in People with HIV: A Pilot Study. Diagnostics (Basel, Switzerland), vol. 12.
  2. Bellini, N., Lodge, R., Pham, T. N. Q., Jain, J., Murooka, T. T., Herschhorn, A., Bernard, N. F., Routy, J.-P., Tremblay, C. L. & Cohen, É. A. (2022). MiRNA-103 downmodulates CCR5 expression reducing human immunodeficiency virus type-1 entry and impacting latency establishment in CD4+ T cells. iScience, vol. 25, p. 105234.
  3. Brunet-Ratnasingham, E., Morou, A., Dubé, M., Niessl, J., Baxter, A. E., Tastet, O., Brassard, N., Ortega-Delgado, G., Charlebois, R., Freeman, G. J., Tremblay, C., Routy, J.-P. & Kaufmann, D. E. (2022). Immune checkpoint expression on HIV-specific CD4+ T cells and response to their blockade are dependent on lineage and function. EBioMedicine, vol. 84, p. 104254.
  4. Arora, A. K., Engler, K., Lessard, D., Kronfli, N., Rodriguez-Cruz, A., Huerta, E., Lemire, B., Routy, J.-P., Wittmer, R., Cox, J., de Pokomandy, A., Del Balso, L., Klein, M., Sebastiani, G., Vedel, I., Quesnel-Vallée, A., & Lebouché, B. (2022). Experiences of Migrant People Living with HIV in a Multidisciplinary HIV Care Setting with Rapid B/F/TAF Initiation and Cost-Covered Treatment: The 'ASAP' Study. Journal of personalized medicine, vol. 12.
  5. Royston, L., Isnard, S., Perrin, N., Sinyavskaya, L., Berini, C., Lin, J., Trottier, B., Baril, J.-G., Chartrand-Lefebvre, C., Tremblay, C., Durand, M. & Routy, J.-P. (2022). Growth differentiation factor-15 as a biomarker of atherosclerotic coronary plaque: Value in people living with and without HIV. Frontiers in cardiovascular medicine, vol. 9, p. 964650.
  6. Ouyang, J., Zaongo, S. D., Harypursat, V., Li, X., Routy, J.-P. & Chen, Y. (2022). SARS-CoV-2 pre-exposure prophylaxis: A potential COVID-19 preventive strategy for high-risk populations, including healthcare workers, immunodeficient individuals, and poor vaccine responders. Frontiers in public health, vol. 10, p. 945448.
  7. Yero, A., Shi, T., Routy, J.-P., Tremblay, C., Durand, M., Costiniuk, C. T. & Jenabian, M.-A. (2022). FoxP3+ CD8 T-cells in acute HIV infection and following early antiretroviral therapy initiation. Frontiers in immunology, vol. 13, p. 962912.
  8. Feng, L., Chen, T., Zhang, J., Wang, Q., Liu, J., Gui, X.-E., Routy, J.-P. & Cao, Q. (2022). Clinical characteristics and outcomes of chronic kidney disease in people living with HIV in a resource limited centre of central China. AIDS research and human retroviruses, vol. 38, p. 726-734.
  9. Lessard, D., Dubé, K., Bilodeau, M., Keeler, P., Margolese, S., Rosenes, R., Sinyavskaya, L., Durand, M., Benko, E., Kovacs, C., Guerlotté, C., Tharao, W., Arnold, K., Masching, R., Taylor, D., Sousa, J., Ostrowski, M., Taylor, J., Kaytes, A., Smith, D., Gianella, S., Chomont, N., Angel, J. B., Routy, J.-P., Cohen, É. A., Lebouché, B. & Costiniuk, C. T. (2022). Willingness of Older Canadians with HIV to Participate in HIV Cure Research Near and After the End of Life: A Mixed-Method Study. AIDS research and human retroviruses, vol. 38, p. 670-682.
  10. Mehraj, V., Ahmed, J. & Routy, J.-P. (2022). The grace of aging with ART: Ex vivo dendritic cell-based immunotherapy restores HIV-specific functional CD8+ T-cells. EBioMedicine, vol. 81, p. 104122.
More on PubMed 

See also

Card image

See profile
Card image

See profile
Card image

See profile
Card image

See profile
Card image

See profile
Card image

See profile