Lab Information

Bertrand Lebouché (MD/PhD)

Centre for Outcomes Research and Evaluation
Department of Family Medicine (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 60%
 Epidemiology: 0%
 Evaluation: 40%
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HIV • adherence • antiretroviral therapy • patient engagement • patient-reported outcome measures • mHealth • HCV • men who have sex with men • HIV prevention

Research Interests

My research focuses on three main axes, drawing on a multidisciplinary model of care and a patient-oriented perspective. First of all, I study HIV/STI testing. Fifteen percent of PLHIV in Canada are undiagnosed. I examined the impact of a community-based rapid HIV-testing site with nurse and community agent teams on attracting vulnerable groups, linking them to care and service appreciation. Secondly, I study sexual health and antiretroviral therapy (ART) as prevention. Sexual health issues in HIV-positive MSM regularly go unaddressed. With parallel studies, I will examine the effect of a sex therapist-led intervention on their adherence, transmission risk, and broader sexual health. Thirdly, I study Optimizing ART. Innovative clinical monitoring tools are needed to detect factors that could interfere with ART adherence early. My I-Score Study will generate an electronic patient-reported outcome measure for use in routine HIV care towards more patient-centered care.

Team Members

Name Position

Latest Publications

  1. Lessard, D., Dube, K., Bilodeau, M., Keeler, P., Margolese, S., Rosenes, R., Sinyavskaya, L., Durand, M., Benko, E., Kovacs, C., Guerlotté, C., Tharao, W. E., Arnold, K., Masching, R., Taylor, D., Sousa, J., Ostrowski, M., Taylor, J., Kaytes, A., Smith, D., Gianella Weibel, S., Chomont, N., Angel, J. B., Routy, J.-P., Cohen, E., Lebouche, B. & Costiniuk, C. T. (2022). Willingness of older Canadians with HIV to participate in HIV cure research near and after the end-of-life: A mixed-method study. AIDS research and human retroviruses.
  2. Xi, M., Bullock, S., Mendelsohn, J. B., Iveniuk, J., Moravan, V., Burchell, A. N., Tan, D. H. S., Daftary, A., Thompson, T., Lebouché, B., Bisaillon, L., Myers, T. & Calzavara, L. (2022). A national recruitment strategy for HIV-serodiscordant partners living in Canada for the Positive Plus One study: a mixed-methods study. BMC public health, vol. 22, p. 832.
  3. Bouabida, K., Malas, K., Talbot, A., Desrosiers, M.-È., Lavoie, F., Lebouché, B., Taghizadeh, N., Normandin, L., Vialaron, C., Fortin, O., Lessard, D. & Pomey, M.-P. (2022). Healthcare Professional Perspectives on the Use of Remote Patient-Monitoring Platforms during the COVID-19 Pandemic: A Cross-Sectional Study. Journal of personalized medicine, vol. 12.
  4. Mendelsohn, J. B., Calzavara, L., Bullock, S., Iveniuk, J., Tan, D. H. S., Burchell, A. N., Bourne, A., Lebouché, B., Daftary, A., Moravan, V., Loutfy, M., Conway, B. & Positive Plus One Study Team (2022). Disclosure of HIV-serodiscordant relationships and association with viral suppression: results from the Positive Plus One study. AIDS care, p. 1-8.
  5. Engler, K., Vicente, S., Mate, K. K. V., Lessard, D., Ahmed, S. & Lebouché, B. (2022). Content validation of a new measure of patient-reported barriers to antiretroviral therapy adherence, the I-Score: results from a Delphi study. Journal of patient-reported outcomes, vol. 6, p. 28.
  6. Iveniuk, J., Calzavara, L., Bullock, S., Mendelsohn, J., Burchell, A., Bisaillon, L., Daftary, A., Lebouché, B., Masching, R., Thompson, T. & Positive Plus One Team (2022). Social capital and HIV-serodiscordance: Disparities in access to personal and professional resources for HIV-positive and HIV-negative partners. SSM - population health, vol. 17, p. 101056.
  7. Gelhorn, H., Garris, C., Arthurs, E., Spinelli, F., Cutts, K., Chua, G. N., Collacott, H., Lebouché, B., Lowman, E., Rice, H. & Heidenreich, S. (2022). Patient and Physician Preferences for Regimen Attributes for the Treatment of HIV in the United States and Canada. Journal of personalized medicine, vol. 12.
  8. Sebastiani, G., Milic, J., Gioe, C., Al Hinai, A. S., Cervo, A., Lebouche, B., Deschenes, M., Cascio, A., Mazzola, G. & Guaraldi, G. (2022). Diagnosis of liver fibrosis in ageing patients with HIV at risk for non-alcoholic fatty liver disease in Italy and Canada: assessment of a two-tier pathway. The lancet. HIV, vol. 9 Suppl 1, p. S4.
  9. Ryan, M., Mendelsohn, J. B., Daftary, A., Yang, M., Bullock, S., Lebouché, B., Calzavara, L. & Positive Plus One Team (2022). Dual pharmaceutical citizenship: Exploring biomedicalization in the daily lives of mixed HIV-serostatus couples in Canada. Social science & medicine (1982), vol. 298, p. 114863.
  10. Ortiz-Paredes, D., Varsaneux, O., Worthington, J., Park, H., MacDonald, S. E., Basta, N. E., Lebouché, B., Cox, J., Ismail, S. J. & Kronfli, N. (2022). Reasons for COVID-19 vaccine refusal among people incarcerated in Canadian federal prisons. PloS one, vol. 17, p. e0264145.
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