Lab Information
Giada Sebastiani (MD)
Senior ScientistCentre for Outcomes Research and Evaluation
Department of Medicine (McGill)
Research Profile
Keywords
Fatty liver • serum liver biomarkers • elastography • HIV • hepatitis C • hepatitis BResearch Interests
My research focuses on screening for liver fibrosis and fatty liver of at-risk populations, including HIV+ patients, patients with diabetes and obesity, women with polycystic ovary syndrome, and patients with inflammatory bowel syndrome. To conduct these studies, I employ serum fibrosis biomarkers and a non-invasive machine, which is ultrasound-based, named Fibroscan. I am also site investigator of multiple global clinical trials for antifibrotic compounds in NASH.Team Members
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Latest Publications
- Cinque, F., Long, C., Dinh, D. A., Gore, G., Swain, M., Ramji, A., Patel, K., Betel, M., Bajaj, H. S., Dasgupta, K., Poder, T. G., Saeed, S. & Sebastiani, G. (2025). Discrete Choice Experiments and Conjoint Analyses in Health Screening Programs for Type 2 Diabetes and Liver Disease: A Scoping Review. Canadian liver journal, vol. 8, p. 63-78.
- Bera, C., Hamdan-Perez, N., Kosick, H.-M., Shengir, M., Sebastiani, G. & Patel, K. (2025). Validation of FIB-4 for the Diagnosis of Liver Cirrhosis in Metabolic Dysfunction-Associated Steatotic Liver Disease. Canadian liver journal, vol. 8, p. 280-283.
- Sebastiani, G., Raggi, P. & Guaraldi, G. (2025). Integrating the care of Metabolic Dysfunction-associated Steatotic Liver Disease into Cardiac Rehabilitation: A Multisystem Approach. The Canadian journal of cardiology.
- Kosick, H.-M., McIntosh, C., Bera, C., Fakhriyehasl, M., Shengir, M., Adeyi, O., Amiri, L., Sebastiani, G., Jhaveri, K. & Patel, K. (2025). Machine learning models using non-invasive tests & B-mode ultrasound to predict liver-related outcomes in metabolic dysfunction-associated steatotic liver disease. Scientific reports, vol. 15, p. 24579.
- Pennisi, G., Di Maria, G., Wai-Sun Wong, V., de Ledinghen, V., Sebastiani, G., Viganò, M., Fracanzani, A. L., Miele, L., Bugianesi, E., Ekstedt, M., D'Ambrosio, R., Ravaioli, F., Schepis, F., Marra, F., Aghemo, A., Svegliati-Baroni, G., Persico, M., Valenti, L., Berzigotti, A., George, J., Armandi, A., Nasr, P., Kechagias, S., Liguori, A., Saltini, D., Mendoza, Y. P., Calvaruso, V., Enea, M., Lin, H., Infantino, G., Masarone, M., Pugliese, N., Tulone, A., Di Marco, V., Cammà, C. & Petta, S. (2025). Impact of first and further decompensation in patients with compensated ACLD due to MASLD. Journal of hepatology.
- Shengir, M., Elgretli, W., Cinque, F., Ramanakumar, A. V., Lombardi, R., Cespiati, A., Fracanzani, A. L., Ballesteros, L., Deschenes, M., Wong, P., Chen, T. & Sebastiani, G. (2025). Metabolic Factors Drive Early Increase in Hepatic Steatosis Despite Improvement in Non-Invasive Fibrosis Markers after Hepatitis C Eradication with Direct-Acting Antivirals. Clinics and research in hepatology and gastroenterology, p. 102639.
- Kronfli, N., Mambro, A., O'Brien, A., Dussault, C., Chalifoux, S., Balso, L. D., Petropoulos, A., Lim, M., Halavrezos, A., Lebouche, B., Sebastiani, G., Klein, M. B. & Cox, J. (2025). A pre-post study of the impact of a multidisciplinary model of care on linkage to hepatitis C care following release from prison: The Beyond Prison Walls study. The International journal on drug policy, vol. 143, p. 104873.
- Lee, T.-H., Wegermann, K., Sutha, K., Cholankeril, G., Chu, C.-Y., Nguyen Galvan, N. T., Rana, A., Goss, J. A., Lambing, T., Cinque, F., Sebastiani, G., Patel, K., Naggie, S. & Wolfe, C. R. (2025). Beyond the HOPE Act: Roadmap to Expanding Kidney and Liver Transplants for People with Human Immunodeficiency Virus Utilizing Grafts from Donors with Human Immunodeficiency Virus. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
- Cinque, F. & Sebastiani, G. (2025). Lifestyle first: tackling MASLD in people living with HIV. The lancet. HIV, vol. 12, p. e394-e395.
- Burnside, J., Cinque, F., Sebastiani, G., Ramji, A., Patel, K., Swain, M. & Saeed, S. (2025). Sex differences in the prevalence and cardiometabolic risk profiles of steatotic liver disease: A Canadian Longitudinal Study on Aging analysis. Canadian journal of public health = Revue canadienne de sante publique.
See also
