Lab Information
Giada Sebastiani (MD)
Senior ScientistCentre for Outcomes Research and Evaluation
Department of Medicine (McGill)
Research Profile
Keywords
Fatty liver • serum liver biomarkers • elastography • HIV • hepatitis C • hepatitis BResearch Interests
My research focuses on screening for liver fibrosis and fatty liver of at-risk populations, including HIV+ patients, patients with diabetes and obesity, women with polycystic ovary syndrome, and patients with inflammatory bowel syndrome. To conduct these studies, I employ serum fibrosis biomarkers and a non-invasive machine, which is ultrasound-based, named Fibroscan. I am also site investigator of multiple global clinical trials for antifibrotic compounds in NASH.Team Members
| Name | Position |
|---|
Latest Publications
- Benmassaoud, A., Bessissow, A., Samoukovic, G., Wong, P., Zhao, X., Deschenes, M., Sebastiani, G., Cabrera, T., Valenti, D., Boucher, L.-M., Pelage, J.-P., Muchantef, K., Cardenas, A., Givis, M. A., White, S., Bousquet-Dion, G., Waked, C., Jacques, J., Rahme, E., Geraci, O., Martel, M., Barkun, A., Maedler-Kron, C. & Chen, Y.-I. (2025). EUS-GUIDED LIVER BIOPSY AND PORTAL PRESSURE MEASUREMENT COMPARED TO TRANSJUGULAR APPROACH: A RANDOMIZED CONTROLLED TRIAL. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
- Patel, K. & Sebastiani, G. (2025). Current and Investigational Biomarkers of Liver Disease in HIV-HBV Co-infection. Current HIV/AIDS reports, vol. 22, p. 46.
- Farina, F., Datta, A., Morin, S. N., Saeed, S., Lebouche, B., Guaraldi, G., Petta, S. & Sebastiani, G. (2025). Intersections of vitamin D deficiency, HIV and chronic liver diseases. HIV medicine.
- Righetti, R., Cinque, F., Lebouché, B., Ramos Ballesteros, L., Routy, J.-P., Klein, M. B., Szabo, J., Cox, J., Falutz, J., Haraoui, L.-P., Costiniuk, C. T., De Pokomandy, A., Pembroke, T., Constante, M., Santos, M. & Sebastiani, G. (2025). Distinct Gut Microbiota Signatures Are Associated with Severity of Metabolic Dysfunction-Associated Steatotic Liver Disease in People with HIV. International journal of molecular sciences, vol. 26.
- Cinque, F., Long, C., Dinh, D. A., Gore, G., Swain, M., Ramji, A., Patel, K., Betel, M., Bajaj, H. S., Dasgupta, K., Poder, T. G., Saeed, S. & Sebastiani, G. (2025). Discrete Choice Experiments and Conjoint Analyses in Health Screening Programs for Type 2 Diabetes and Liver Disease: A Scoping Review. Canadian liver journal, vol. 8, p. 63-78.
- Bera, C., Hamdan-Perez, N., Kosick, H.-M., Shengir, M., Sebastiani, G. & Patel, K. (2025). Validation of FIB-4 for the Diagnosis of Liver Cirrhosis in Metabolic Dysfunction-Associated Steatotic Liver Disease. Canadian liver journal, vol. 8, p. 280-283.
- Sebastiani, G., Raggi, P. & Guaraldi, G. (2025). Integrating the care of Metabolic Dysfunction-associated Steatotic Liver Disease into Cardiac Rehabilitation: A Multisystem Approach. The Canadian journal of cardiology.
- Kosick, H.-M., McIntosh, C., Bera, C., Fakhriyehasl, M., Shengir, M., Adeyi, O., Amiri, L., Sebastiani, G., Jhaveri, K. & Patel, K. (2025). Machine learning models using non-invasive tests & B-mode ultrasound to predict liver-related outcomes in metabolic dysfunction-associated steatotic liver disease. Scientific reports, vol. 15, p. 24579.
- Pennisi, G., Di Maria, G., Wai-Sun Wong, V., de Ledinghen, V., Sebastiani, G., Viganò, M., Fracanzani, A. L., Miele, L., Bugianesi, E., Ekstedt, M., D'Ambrosio, R., Ravaioli, F., Schepis, F., Marra, F., Aghemo, A., Svegliati-Baroni, G., Persico, M., Valenti, L., Berzigotti, A., George, J., Armandi, A., Nasr, P., Kechagias, S., Liguori, A., Saltini, D., Mendoza, Y. P., Calvaruso, V., Enea, M., Lin, H., Infantino, G., Masarone, M., Pugliese, N., Tulone, A., Di Marco, V., Cammà, C. & Petta, S. (2025). Impact of first and further decompensation in patients with compensated ACLD due to MASLD. Journal of hepatology.
- Shengir, M., Elgretli, W., Cinque, F., Ramanakumar, A. V., Lombardi, R., Cespiati, A., Fracanzani, A. L., Ballesteros, L., Deschenes, M., Wong, P., Chen, T. & Sebastiani, G. (2025). Metabolic Factors Drive Early Increase in Hepatic Steatosis Despite Improvement in Non-Invasive Fibrosis Markers after Hepatitis C Eradication with Direct-Acting Antivirals. Clinics and research in hepatology and gastroenterology, p. 102639.
See also
