Lab Information
Giada Sebastiani (MD)
Senior ScientistCentre for Outcomes Research and Evaluation
Department of Medicine (McGill)
Research Profile
Keywords
Fatty liver • serum liver biomarkers • elastography • HIV • hepatitis C • hepatitis BResearch Interests
My research focuses on screening for liver fibrosis and fatty liver of at-risk populations, including HIV+ patients, patients with diabetes and obesity, women with polycystic ovary syndrome, and patients with inflammatory bowel syndrome. To conduct these studies, I employ serum fibrosis biomarkers and a non-invasive machine, which is ultrasound-based, named Fibroscan. I am also site investigator of multiple global clinical trials for antifibrotic compounds in NASH.Team Members
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Latest Publications
- Younossi, Z. M., de Avila, L., Petta, S., Hagström, H., Kim, S. U., Nakajima, A., Crespo, J., Castera, L., Alkhouri, N., Zheng, M.-H., Treeprasertsuk, S., Ananchuensook, P., Shalimar, D., Tsochatzis, E., Trivikrama, S. K., Balakumaran, L. K., Fan, J.-G., Roberts, S. K., Alswat, K., Wong, V.-W., Yilmaz, Y., Dunn, W., Francque, S., Cordie, A., Yu, M.-L., Ekstedt, M., Goh, G.-B., Oliveira, C. P., Pessoa, M. G., Chan, W. K., Fernandez, M. I. C., Duseja, A., Arab, J. P., Papatheodoridis, G., Sebastiani, G., Villela-Nogueira, C., D'Ambrosio, R., Lampertico, P., Alnaamani, K., Holleboom, A. G., Valsan, A., Venu, A., El-Kassas, M., Pennisi, G., Shang, Y., Liu, W.-Y., Lee, H. W., Kobayashi, T., Kakizaki, S., Caussy, C., Pearlman, B., Iruzubieta, P., Nadeem, R., Cinque, F., Neonaki, A., Zoncapé, M., Yang, R.-X., Song, S. J., Dunn, N., Gadi, Z., Yeh, M.-L., The, K.-K., Mahadeva, S., Fabian, L. G., Almohsen, A., Leite, N., Pugliese, N., Vessby, J., Xie, C., Choudhary, N. S., Friend, E., Poca, M., Kawaguchi, T., Russo, F. P., Gadano, A., Diaz, L. A., Singal, A. K., Segrestin, B., Gunn, N., Mauricio, D., Arrese, M., Fracanzani, A., Brian Lam, P. A., Racila, A., Alqahtani, S. A., Stepanova, M. & Global NASH/MASH Council (GNC) (2025). Global performance of non-invasive tests in MASLD: Insights from the G-MASLD study. Hepatology (Baltimore, Md.).
- Lefebvre, T. L., Volniansky, A., Petitclerc, L., Montagnon, E., Sebastiani, G., Giard, J.-M., Sylvestre, M.-P., Nguyen, B. N., Gilbert, G., Cloutier, G. & Tang, A. (2025). Harnessing Intrinsic Cardiac Motion vs. External Mechanical Vibrations: A Comparison of MRI Cine-Tagging and MR Elastography for Liver Fibrosis Assessment. The British journal of radiology.
- Benmassaoud, A., Bessissow, A., Samoukovic, G., Wong, P., Zhao, X., Deschenes, M., Sebastiani, G., Cabrera, T., Valenti, D., Boucher, L.-M., Pelage, J.-P., Muchantef, K., Cardenas, A., Givis, M. A., White, S., Bousquet-Dion, G., Waked, C., Jacques, J., Rahme, E., Geraci, O., Martel, M., Barkun, A., Maedler-Kron, C. & Chen, Y.-I. (2025). EUS-GUIDED LIVER BIOPSY AND PORTAL PRESSURE MEASUREMENT COMPARED TO TRANSJUGULAR APPROACH: A RANDOMIZED CONTROLLED TRIAL. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
- Patel, K. & Sebastiani, G. (2025). Current and Investigational Biomarkers of Liver Disease in HIV-HBV Co-infection. Current HIV/AIDS reports, vol. 22, p. 46.
- Farina, F., Datta, A., Morin, S. N., Saeed, S., Lebouche, B., Guaraldi, G., Petta, S. & Sebastiani, G. (2025). Intersections of vitamin D deficiency, HIV and chronic liver diseases. HIV medicine.
- Righetti, R., Cinque, F., Lebouché, B., Ramos Ballesteros, L., Routy, J.-P., Klein, M. B., Szabo, J., Cox, J., Falutz, J., Haraoui, L.-P., Costiniuk, C. T., De Pokomandy, A., Pembroke, T., Constante, M., Santos, M. & Sebastiani, G. (2025). Distinct Gut Microbiota Signatures Are Associated with Severity of Metabolic Dysfunction-Associated Steatotic Liver Disease in People with HIV. International journal of molecular sciences, vol. 26.
- Cinque, F., Long, C., Dinh, D. A., Gore, G., Swain, M., Ramji, A., Patel, K., Betel, M., Bajaj, H. S., Dasgupta, K., Poder, T. G., Saeed, S. & Sebastiani, G. (2025). Discrete Choice Experiments and Conjoint Analyses in Health Screening Programs for Type 2 Diabetes and Liver Disease: A Scoping Review. Canadian liver journal, vol. 8, p. 63-78.
- Bera, C., Hamdan-Perez, N., Kosick, H.-M., Shengir, M., Sebastiani, G. & Patel, K. (2025). Validation of FIB-4 for the Diagnosis of Liver Cirrhosis in Metabolic Dysfunction-Associated Steatotic Liver Disease. Canadian liver journal, vol. 8, p. 280-283.
- Sebastiani, G., Raggi, P. & Guaraldi, G. (2025). Integrating the care of Metabolic Dysfunction-associated Steatotic Liver Disease into Cardiac Rehabilitation: A Multisystem Approach. The Canadian journal of cardiology.
- Kosick, H.-M., McIntosh, C., Bera, C., Fakhriyehasl, M., Shengir, M., Adeyi, O., Amiri, L., Sebastiani, G., Jhaveri, K. & Patel, K. (2025). Machine learning models using non-invasive tests & B-mode ultrasound to predict liver-related outcomes in metabolic dysfunction-associated steatotic liver disease. Scientific reports, vol. 15, p. 24579.
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