Lab Information
Jean-Pierre Routy (MD)
Senior ScientistCentre for Translational Biology
Department of Medicine (McGill)
Research Profile
Keywords
HIV • vaccine • lymphoma • T cells • cytokinesResearch Interests
My research focuses on HIV pathogenesis aiming at finding an HIV cure. Improving knowledge in immune tolerance in cancer and in immune privileged sites (central nervous system, testis) will be key to develop strategy to conquer cancers and auto-immune diseases.Team Members
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Latest Publications
- Doyon-Laliberté, K., Aranguren, M., Chagnon-Choquet, J., Batraville, L.-A., Dagher, O., Richard, J., Paniconi, M., Routy, J.-P., Tremblay, C., Quintal, M.-C., Brassard, N., Kaufmann, D. E., Finzi, A., Poudrier, J. & Roger, M. (2023). Excess BAFF May Impact HIV-1-Specific Antibodies and May Promote Polyclonal Responses Including Those from First-Line Marginal Zone B-Cell Populations. Current issues in molecular biology, vol. 46, p. 25-43.
- Ramani, H., Gosselin, A., Bunet, R., Jenabian, M. A., Sylla, M., Pagliuzza, A., Chartrand-Lefebvre, C., Routy, J. P., Goulet, J. P., Thomas, R., Trottier, B., Martel-Laferrière, V., Fortin, C., Chomont, N., Fromentin, R., Landay, A., Durand, M., Ancuta, P., El-Far, M. & Tremblay, C. (2023). IL-32 Drives the Differentiation of Cardiotropic CD4+ T-Cells Carrying HIV DNA in People Living with HIV. The Journal of infectious diseases.
- Bedier, H., Isnard, S., Maedler-Kron, C. & Routy, J.-P. (2023). Long-Term Tolerance and Efficacy of Siltuximab (Anti-IL-6) in a Young Adult with Idiopathic Multicentric Castleman Disease During COVID-19. European journal of case reports in internal medicine, vol. 10, p. 004098.
- Routy, J.-P. & Isnard, S. (2023). [Forty years old and not quarantined: where are we with HIV-focused research?]. Virologie (Montrouge, France), vol. 27, p. 265-268.
- Ouyang, J., Yan, J., Zhou, X., Isnard, S., Tang, S., Costiniuk, C. T., Chen, Y., Routy, J.-P. & Chen, Y. (2023). The Influence of Oral Terbinafine on Gut Fungal Microbiome Composition and Microbial Translocation in People Living with HIV Treated for Onychomycosis. Journal of fungi (Basel, Switzerland), vol. 9.
- Hammond, K., Lee, T., Vulesevic, B., Singer, J., Needham, J., Burchell, A. N., Samji, H., Walmsley, S., Hull, M., Jenabian, M.-A., Routy, J.-P., Margolese, S., Mandarino, E., Anis, A. H., Cooper, C. L. & Costiniuk, C. T. (2023). Preventative behaviours and COVID-19 infection in a Canadian cohort of people living with HIV. AIDS research and therapy, vol. 20, p. 73.
- Nayyerabadi, M., Fourcade, L., Joshi, S. A., Chandrasekaran, P., Chakravarti, A., Massé, C., Paul, M.-L., Houle, J., Boubekeur, A. M., DuSablon, C., Boudreau, V., Bovan, D., Darbinian, E., Coleman, E. A., Vinci, S., Routy, J.-P., Hétu, P.-O., Poudrier, J. & Falcone, E. L. (2023). Vaccination after developing long COVID: impact on clinical presentation, viral persistence and immune responses. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, vol. 136, p. 136-145.
- Dubé, M., Tastet, O., Dufour, C., Sannier, G., Brassard, N., Delgado, G.-G., Pagliuzza, A., Richard, C., Nayrac, M., Routy, J.-P., Prat, A., Estes, J. D., Fromentin, R., Chomont, N. & Kaufmann, D. E. (2023). Spontaneous HIV expression during suppressive ART is associated with the magnitude and function of HIV-specific CD4+ and CD8+ T cells. Cell host & microbe, vol. 31, p. 1507-1522.e5.
- Dufour, C., Ruiz, M. J., Pagliuzza, A., Richard, C., Shahid, A., Fromentin, R., Ponte, R., Cattin, A., Wiche Salinas, T. R., Salahuddin, S., Sandstrom, T., Schinkel, S. B., Costiniuk, C. T., Jenabian, M.-A., Ancuta, P., Routy, J.-P., Cohen, É. A., Brumme, Z. L., Power, C., Angel, J. B. & Chomont, N. (2023). Near full-length HIV sequencing in multiple tissues collected postmortem reveals shared clonal expansions across distinct reservoirs during ART. Cell reports, vol. 42, p. 113053.
- Lessard, D., Lebouché, B., Morneau, A., Bilodeau, M., Rosenes, R., Sanders, J., Chomont, N., Keeler, P., Dubé, K., Margolese, S., Jenabian, M.-A., Power, C., Routy, J.-P., B Angel, J., A Cohen, E. & T Costiniuk, C. (2023). Donating One's Body to HIV Cure Research Through Canadian Medical Assistance in Dying: A Case Study. Current HIV research, vol. 21, p. 264-267.
See also
