Lab Information

Talat Bessissow (MD/PhD)

Associate Investigator
Clinical Research Unit
Department of Medicine (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 100%
 Epidemiology: 0%
 Evaluation: 0%
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Keywords

Crohn's disease • ulcerative colitis • mucosal healing • neoplasia • pathogenesis

Research Interests

My research focuses on the role of mucosal healing in the treatment of inflammatory bowel diseases. I am also looking at identifying factor that predict disease relapse.


Team Members

Name Position

Latest Publications

  1. Bacsur, P., Wetwittayakhlang, P., Resál, T., Földi, E., Vasas, B., Farkas, B., Rutka, M., Bessissow, T., Afif, W., Bálint, A., Fábián, A., Bor, R., Szepes, Z., Farkas, K., Lakatos, P. L. & Molnár, T. (2024). Accuracy of the Pancolonic Modified Mayo Score in predicting the long-term outcomes of ulcerative colitis: a promising scoring system. Therapeutic advances in gastroenterology, vol. 17, p. 17562848241239606.
  2. Wetwittayakhlang, P., Bessissow, T. & Lakatos, P. L. (2024). Novel and emerging drugs for the treatment of Crohn's disease: a review of phase II and III trials. Expert opinion on emerging drugs, vol. 29, p. 19-34.
  3. Vuyyuru, S. K., Nguyen, T. M., Murad, M. H., Narula, N., Bessissow, T., Zou, G., McCurdy, J. D., Peyrin-Biroulet, L., Danese, S., Ma, C., Singh, S. & Jairath, V. (2024). Comparative Efficacy of Advanced Therapies for Achieving Endoscopic Outcomes in Crohn's Disease: A Systematic Review and Network Meta-Analysis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
  4. Alenezi, T., Marcus, V. & Bessissow, T. (2023). A Case Report and Literature Review of a Rare Jejunal Solitary Peutz-Jeghers-Type Polyp Resected Endoscopically in an Elderly Patient Presenting with Subacute Gastrointestinal Bleeding. Case reports in gastrointestinal medicine, vol. 2023, p. 2391602.
  5. Vuyyuru, S. K., Ma, C., Sharma, T., Nguyen, T. M., Bessissow, T., Narula, N., Singh, S., Rieder, F. & Jairath, V. (2023). Characteristics of Interventional Trials for Patients Living With Intestinal Stoma Registered in ClinicalTrials.gov With a Focus on Inflammatory Bowel Disease. Inflammatory bowel diseases.
  6. McCurdy, J., Munir, J., Parlow, S., Reid, J., Yanofsky, R., Alenezi, T., Meserve, J., Becker, B., Lahijanian, Z., Eddin, A. H., Mallick, R., Ramsay, T., Rosenfeld, G., Bessissow, A., Bessissow, T., Jairath, V., Singh, S., Bruining, D. H., Macdonald, B. & Canadian IBD Research Consortium (CIRC) (2023). Development of an MRI-based prediction model for anti-TNF treatment failure in perianal Crohn's disease: A multicenter study. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
  7. Bessissow, T., Narula, N., Ma, C., In, T. S. H., Eberg, M., Karra, K., Jairath, V. & Canadian IBD Research Consortium (2024). Real-world effectiveness and safety of ustekinumab in bio-naive patients with moderate-to-severe Crohn's disease: A Canadian multi-center study. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, vol. 56, p. 61-69.
  8. Shehab, M., Al Akram, S., Hassan, A., Alrashed, F., Jairath, V. & Bessissow, T. (2024). Histological Disease Activity as Predictor of Clinical Relapse, Hospitalization, and Surgery in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis. Inflammatory bowel diseases, vol. 30, p. 563-572.
  9. Wetwittayakhlang, P., Karkout, K., Wongcha-Um, A., Tselekouni, P., Al-Jabri, R., Afif, W., Wild, G., Bitton, A., Bessissow, T. & Lakatos, P. L. (2024). Clinical efficacy and nocebo effect following non-medical biosimilar switch in patients with inflammatory bowel disease: A prospective observational study. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, vol. 56, p. 35-42.
  10. Khanna, R., Ma, C., Hogan, M., Zou, G., Bessissow, T., Bressler, B., Colombel, J.-F., Danese, S., Daperno, M., East, J. E., Hookey, L., Loftus, E. V., McDonald, J. W. D., Panaccione, R., Peyrin-Biroulet, L., Rutter, M., Sands, B. E., Vermeire, S., Rémillard, J., McFarlane, S. C., Sandborn, W. J., D'Haens, G. R., Feagan, B. G. & Jairath, V. (2023). Standardizing Scoring Conventions for Crohn's Disease Endoscopy: An International RAND/UCLA Appropriateness Study. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 21, p. 2938-2950.e6.
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See also

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Peter
Lakatos


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Waqqas
Afif


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Alain
Bitton


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Paul
Brassard


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Jean-Pierre
Routy


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Giada
Sebastiani


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