Lab Information

Talat Bessissow (MD/PhD)

Associate Investigator
Clinical Research Unit
Department of Medicine (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 100%
 Epidemiology: 0%
 Evaluation: 0%
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Crohn's disease • ulcerative colitis • mucosal healing • neoplasia • pathogenesis

Research Interests

My research focuses on the role of mucosal healing in the treatment of inflammatory bowel diseases. I am also looking at identifying factor that predict disease relapse.

Team Members

Name Position

Latest Publications

  1. Shehab, M., Alrashed, F., Heron, V., Restellini, S. & Bessissow, T. (2022). Comparative Efficacy of Biologic Therapies for Inducing Response and Remission in Fistulizing Crohn's Disease: Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Inflammatory bowel diseases.
  2. Hahn, G. D., Wetwittayakhlang, P., Afif, W., Bessissow, T. & Lakatos, P. L. (2022). Hereditary Nonpolyposis Colorectal Cancer in Association with Crohn's Disease and Lynch Syndrome: The Importance of a Strict Endoscopic Surveillance. Case reports in gastroenterology, vol. 16, p. 116-121.
  3. Hahn, G. D., Golovics, P. A., Wetwittayakhlang, P., Al Khoury, A., Bessissow, T. & Lakatos, P. L. (2022). Is There a Best First Line Biological/Small Molecule in IBD: Are We Ready for Sequencing?. Biomedicines, vol. 10.
  4. Xiao, Y., Benoit, N., Sedano, R., Jairath, V., Narula, N., McCurdy, J. D., Rosenfeld, G., Afif, W., Lakatos, P. L. & Bessissow, T. (2022). Effectiveness of Tofacitinib for Hospitalized Patients with Acute Severe Ulcerative Colitis: Case Series. Digestive diseases and sciences.
  5. Golovics, P. A., Verdon, C., Wetwittayakhlang, P., Filliter, C., Gonczi, L., Hahn, G. D., Wild, G. E., Afif, W., Bitton, A., Bessissow, T., Brassard, P. & Lakatos, P. L. (2022). Increased Prevalence of Myocardial Infarction and Stable Stroke Proportions in Patients with Inflammatory Bowel Diseases in Quebec in 1996-2015. Journal of clinical medicine, vol. 11.
  6. Isnard, S., Fombuena, B., Ouyang, J., Royston, L., Lin, J., Bu, S., Sheehan, N., Lakatos, P. L., Bessissow, T., Chomont, N., Klein, M., Lebouché, B., Costiniuk, C. T., Routy, B., Marette, A., Routy, J.-P. & Camu Camu Study Group (2022). Camu Camu effects on microbial translocation and systemic immune activation in ART-treated people living with HIV: protocol of the single-arm non-randomised Camu Camu prebiotic pilot study (CIHR/CTN PT032). BMJ open, vol. 12, p. e053081.
  7. Wetwittayakhlang, P., Lontai, L., Gonczi, L., Golovics, P. A., Hahn, G. D., Bessissow, T. & Lakatos, P. L. (2021). Treatment Targets in Ulcerative Colitis: Is It Time for All In, including Histology?. Journal of clinical medicine, vol. 10.
  8. Wetwittayakhlang, P., Albader, F., Golovics, P. A., Hahn, G. D., Bessissow, T., Bitton, A., Afif, W., Wild, G. & Lakatos, P. L. (2021). Clinical Outcomes of COVID-19 and Impact on Disease Course in Patients with Inflammatory Bowel Disease. Canadian journal of gastroenterology & hepatology, vol. 2021, p. 7591141.
  9. Wetwittayakhlang, P., Golovics, P. A., Afif, W., Bessissow, T. & Lakatos, P. L. (2021). Tofacitinib-Associated Iatrogenic Kaposi Sarcoma in a Patient With Ulcerative Colitis. ACG case reports journal, vol. 8, p. e00678.
  10. Battat, R., Qatomah, A., Kopylov, U., Wyse, J., Cohen, A., Afif, W., Lakatos, P. L., Seidman, E., Bitton, A. & Bessissow, T. (2022). Fucosyltransferase 2 Mutations Are Associated With a Favorable Clinical Course in Crohn's Disease. Journal of clinical gastroenterology, vol. 56, p. e166-e170.
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