Lab Information
Alain Bitton (MD)
InvestigatorClinical Research Unit
Department of Medicine (McGill)
Research Profile
Keywords
Crohn's disease • ulcerative colitis • psychosocial • biologic markers • geneticsTeam Members
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Latest Publications
- Mu, K., Xue, M., Huynh, H. Q., Griffiths, A. M., Turner, D., Moayyedi, P., Steinhart, A. H., Dieleman, L. A., Deslandres, C., Bitton, A., Mack, D. R., Jacobson, K., Cino, M., Aumais, G., Panaccione, R., Bressler, B., Lee, S.-H., Turpin, W., Croitoru, K. & Crohn's and Colitis Canada Genetics Environment Microbial Project Research Consortium (2026). Serum thiol redox-related alterations in asymptomatic first-degree relatives are associated with future Crohn's disease. Redox biology, vol. 94, p. 104207.
- Nadeem, H., Alsaeid, M., Bitton, A., Nadeem, H. & Lakatos, P. L. (2026). Extensive Colonic Pseudopolyposis Leading to Protein-Losing Enteropathy and Severe Hypoalbuminemia With Refractory Ulcerative Colitis. ACG case reports journal, vol. 13, p. e02011.
- Bernstein, C. N., Nugent, Z., Panaccione, R., Marshall, D. A., Kaplan, G. G., Vanner, S., Dieleman, L. A., Graff, L. A., Otley, A., Jones, J., Buresi, M., Murthy, S., Borgaonkar, M., Bressler, B., Bitton, A., Croitoru, K., Sidani, S., Fernandes, A. & Moayyedi, P. (2026). Patient-reported Symptoms Are Independent of Extent of Disease in Longstanding Ulcerative Colitis: Magic in Imagine. Journal of clinical gastroenterology, vol. 60, p. 442-448.
- Kritzinger, J., Candel, I., Kotrri, G., Nadeem, H., Afif, W., Bitton, A., Wild, G., Bessissow, T. & Lakatos, P. L. (2025). Clinical outcomes and drug sustainability after non-medical switch from ustekinumab originator to biosimilars in inflammatory bowel disease. World journal of gastroenterology, vol. 31, p. 114355.
- Gettler, K., Nagpal, S., Washburn, S., Tastad, C., Zhang, J., Sabic, K., Lazarev, M., Bitton, A., Cohen, R., Schwartz, M. B., Barrie, A., Gu, P., Fleshner, P., Bao, M., Hernández-Rocha, C., McCauley, J., Abreu, M., Kugathasan, S., McGovern, D. P., Brant, S. R., Duerr, R. H., Silverberg, M. S., Rioux, J. D., Gibson, G. & Cho, J. H. (2026). Postoperative Ileum Transcriptomics Implicate Sex-Biased Mechanisms in Crohn's Disease Recurrence. Gastroenterology, vol. 170, p. 511-522.
- Ongay, J., Candel, I., Bitton, A., Afif, W., Bessissow, T. & Lakatos, P. L. (2025). Case Report: Secukinumab (Interleukin-17 Inhibitor) and Ulcerative Colitis Flare - the Double-Edged Sword. Case reports in gastroenterology, vol. 19, p. 637-643.
- Drügg Hahn, G., Lakatos, P. L., Maedler-Kron, C., Marcus, V., Afif, W., Wild, G., Bitton, A., Flores, C., de Magalhães Francesconi, C. F. & Bessissow, T. (2025). Defining Fecal Calprotectin Cutoffs That Predict Endoscopic and Histologic Remission in Patients With Ulcerative Colitis. Inflammatory bowel diseases, vol. 31, p. 2977-2985.
- Xue, M., Lee, S.-H., Shao, J., Leibovitzh, H., Huynh, H. Q., Griffiths, A. M., Turner, D., Madsen, K. L., Moayyedi, P., Steinhart, A. H., Silverberg, M. S., Deslandres, C., Bitton, A., Mack, D. R., Jacobson, K., Ropeleski, M. J., Cino, M., Aumais, G., Bernstein, C. N., Panaccione, R., Bressler, B., Espin-Garcia, O., Xu, W., Turpin, W., Croitoru, K. & Crohn’s and Colitis Canada Genetics Environment Microbial Project Research Consortium (2025). Metabolomics reveal distinct molecular pathways associated with future risk of Crohn's Disease. Gut microbes, vol. 17, p. 2546998.
- Bhérer, C., Grenier, J.-C., Pelletier, J., Boucher, G., Gagnon, G., Goyette, P., Ashton-Beaucage, D., Stevens, C., Battat, R., Bitton, A., Campeau, P. M., Laprise, C., NIDDK IBD Genetics Consortium, Quebec IBD Genetics Consortium , iGenoMed Consortium , Huang, H., Daly, M., Taliun, D., Hussin, J. G., Mooser, V. & Rioux, J. D. (2025). Frequency enrichment of coding variants in a French-Canadian founder population and its implication for inflammatory bowel diseases. medRxiv : the preprint server for health sciences.
- Li Fraine, S., Marcus, V., Kron, C. M., Lakatos, P. L., Afif, W., Bitton, A., Wild, G. & Bessissow, T. (2025). Impact of Individual Colonic Segment Histological Activity on Disease Relapse in Patients with Ulcerative Colitis. Journal of clinical medicine, vol. 14.
See also
