Lab Information
Alain Bitton (MD)
InvestigatorClinical Research Unit
Department of Medicine (McGill)
Research Profile
Keywords
Crohn's disease • ulcerative colitis • psychosocial • biologic markers • geneticsTeam Members
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Latest Publications
- De Marco, D., Heron, V., Bitton, A., Bessissow, T., Lakatos, P., Wild, G. & Afif, W. (2025). Assessing the role of ustekinumab dose escalation in Crohn's disease patients with loss of response: an observational study. Journal of the Canadian Association of Gastroenterology, vol. 8, p. 97-102.
- Rioux, J. D., Boucher, G., Forest, A., Bouchard, B., Coderre, L., Daneault, C., Frayne, I. R., Legault, J. T., Bitton, A., Ananthakrishnan, A., Lesage, S., Xavier, R. J., Des Rosiers, C. & iGenoMed Consortium (2025). Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti-integrin therapy. Immunology and cell biology.
- Bernstein, C. N., Nugent, Z., Panaccione, R., Marshall, D. A., Kaplan, G. G., Dieleman, L. A., Vanner, S., Graff, L. A., Otley, A., Jones, J., Buresi, M., Murthy, S., Borgaonkar, M., Bressler, B., Bitton, A., Croitoru, K., Sidani, S., Fernandes, A. & Moayyedi, P. (2025). Symptoms in Persons With Either Active or Inactive Crohn's Disease Are Agnostic to Disease Phenotype: The Magic in Imagine Study. Journal of clinical gastroenterology.
- Di Fonzo, D. M. P., Alabdulkarim, B., Yanofsky, R., Abduallah, Y., Golovics, P., Lakatos, P. L., Bitton, A., Wild, G., Afif, W. & Bessissow, T. (2024). Association Between Serum Ustekinumab Concentrations and Endoscopic Disease Activity in Moderate-to-Severe Crohn's Disease Patients. Crohn's & colitis 360, vol. 6, p. otae071.
- Lee, S.-H., Bushra, M., Qiu, L., Griffiths, A. M., Turpin, W., Croitoru, K., Crohn’s and Colitis Canada-Genetic, Environmental, Microbial (CCC-GEM) Project Research Consortium, Lee, S.-H., Bushra, M., Qiu, L., Shao, J., Olivera, P. A., Leibovitzh, H., Xue, M., Xu, W., Espin-Garcia, O., Amuais, G. L., Huynh, H. Q., Panaccione, R., Steinhart, A. H., Cino, M., Mack, D., Marshall, J., Ropeleski, M., Bitton, A., Jacobson, K., McGrath, J., Yerushalmi, B., Abreu, M. T., Bernstein, C. N., Radford-Smith, G., Lees, C., Turner, D., Madsen, K., Guttman, D. S., Silverberg, M., Griffiths, A. M., Moayyedi, P., Turpin, W., Beck, P., Dieleman, L., Feagan, B. G., Kaplan, G., Krause, D. O., Seidman, E., Snapper, S., Stadnyk, A., Surette, M., Walters, T., Vallance, B., Critch, J., Denson, L., Deslandres, C., El-Matary, W., Herfarth, H., Higgins, P., Hyams, J., Otley, A., Hedin, C., Hussey, S., Keljo, D., Kevans, D., Murthy, S., Parekh, N., Plamondon, S., Rosh, J., Rubin, D., Schultz, M., Siegel, C. & Croitoru, K. (2025). Early Life Exposure to Parental Crohn's Disease Is Associated With Offspring's Gut Microbiome, Gut Permeability, and Increased Risk of Future Crohn's Disease. Gastroenterology, vol. 168, p. 385-388.e3.
- Rioux, J. D., Boucher, G., Forest, A., Bouchard, B., Coderre, L., Daneault, C., Frayne, I. R., Legault, J. T., iGenoMed Consortium, Bitton, A., Ananthakrishnan, A., Lesage, S., Xavier, R. J. & Des Rosiers, C. (2024). A pilot study to identify blood-based markers associated with response to treatment with Vedolizumab in patients with Inflammatory Bowel Disease. medRxiv : the preprint server for health sciences.
- Ivison, S., Boucher, G., Zheng, G., Garcia, R. V., Kohen, R., Bitton, A., Rioux, J. D., Levings, M. K. & iGenoMed Consortium (2024). Improving Reliability of Immunological Assays by Defining Minimal Criteria for Cell Fitness. ImmunoHorizons, vol. 8, p. 622-634.
- Olivera, P. A., Martinez-Lozano, H., Leibovitzh, H., Xue, M., Neustaeter, A., Espin-Garcia, O., Xu, W., Madsen, K. L., Guttman, D. S., Bernstein, C. N., Yerushalmi, B., Hyams, J. S., Abreu, M. T., Marshall, J. K., Wrobel, I., Mack, D. R., Jacobson, K., Bitton, A., Aumais, G., Panacionne, R., Dieleman, L. A., Silverberg, M. S., Steinhart, A. H., Moayyedi, P., Turner, D., Griffiths, A. M., Turpin, W., Lee, S.-H., Croitoru, K. & Crohn’s and Colitis Canada (CCC) Genetic, Environmental, Microbial (GEM) Project Research Consortium (2025). Healthy first-degree relatives from multiplex families versus simplex families have a higher subclinical intestinal inflammation, a distinct fecal microbial signature, and harbor a higher risk of developing Crohn's disease. Gastroenterology, vol. 168, p. 99-110.e2.
- Rocha, C.-H., Turpin, W., Borowski, K., Stempak, J. M., Sabic, K., Gettler, K., Tastad, C., Chasteau, C., Korie, U., Hanna, M., Khan, A., Mengesha, E., Bitton, A., Schwartz, M. B., Barrie, A., Datta, L. W., Lazarev, M., Brant, S. R., Rioux, J. D., McGovern, D. P. B., Duerr, R. H., Schumm, L. P., Cho, J. H. & Silverberg, M. S. (2025). After surgically induced remission, ileal and colonic mucosa-associated microbiota predicts Crohn's disease recurrence. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 23, p. 612-620.e10.
- Xue, M., Leibovitzh, H., Jingcheng, S., Neustaeter, A., Dong, M., Xu, W., Espin-Garcia, O., Griffiths, A. M., Steinhart, A. H., Turner, D., Huynh, H. Q., Dieleman, L. A., Panaccione, R., Aumais, G., Bressler, B., Bitton, A., Murthy, S., Marshall, J. K., Hyams, J. S., Otley, A., Bernstein, C. N., Moayyedi, P., El-Matary, W., Fich, A., Denson, L. A., Ropeleski, M. J., Abreu, M. T., Deslandres, C., Cino, M., Avni-Biron, I., Lee, S.-H., Turpin, W., CCC GEM Project Research Consortium & Croitoru, K. (2024). Environmental Factors Associated with Risk of Crohn's Disease Development in the CCC-GEM Project. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 22, p. 1889-1897.e12.
See also
