Lab Information

Elena Netchiporouk (MD/MSc)

Junior Scientist
Centre for Translational Biology
Department of Medicine (McGill)

Research Profile

 Fundamental: 50%
 Clinical: 20%
 Epidemiology: 30%
 Evaluation: 0%
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Keywords

Chronic spontaneous urticaria • scleroderma • morphea • systemic sclerosis • skin fibrosis

Research Interests

The incidence of autoimmune diseases affecting the skin and/or internal organs is rising steadily, but at a rate that cannot be explained by genetics alone. This argues for the importance of environmental causes in disease initiation and, possibly, progression. Pollutants and microorganisms (e.g., viruses) may directly damage our cells and elicit production of auto-antibodies by our immune system against our own cells. My research program focuses on understanding the interaction between environment and autoimmune diseases affecting the skin, specifically chronic urticaria and systemic sclerosis. While both are autoimmune in nature, they are completely different with respect to their clinical presentation and prognosis, which makes them ideal to study in parallel.


Team Members

Name Position

Latest Publications

  1. Sanchez, E. G., Ramos, C., Ratnarajah, K., Bravo, F. P., Del Solar, M. A., Le, M. & Netchiporouk, E. (2022). Adenopathy and extensive skin patch overlying plasmacytoma syndrome-the clue to early diagnosis of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes: A case series and literature review. SAGE open medical case reports, vol. 10, p. 2050313X221091602.
  2. Prosty, C., Guirguis, J., Chergui, M., Afif, W. & Netchiporouk, E. (2022). Epidermolysis bullosa acquisita treated with ustekinumab: A case report. SAGE open medical case reports, vol. 10, p. 2050313X221091600.
  3. D'Aguanno, K., Gabrielli, S., Ouchene, L., Muntyanu, A., Ben-Shoshan, M., Zhang, X., Iannattone, L. & Netchiporouk, E. (2022). Omalizumab for the Treatment of Bullous Pemphigoid: A Systematic Review of Efficacy and Safety. Journal of cutaneous medicine and surgery, p. 12034754221089267.
  4. Ghazal, S., Ridha, Z., D'Aguanno, K., Nassim, D., Quaiattini, A., Netchiporouk, E., Poulin, Y., Kalia, S., Marcoux, D., Piguet, V. & Jack, C. (2022). Treatment Guidelines for Atopic Dermatitis Since the Approval of Dupilumab: A Systematic Review and Quality Appraisal Using AGREE-II. Frontiers in medicine, vol. 9, p. 821871.
  5. Prosty, C., Gabrielli, S., Mule, P., Le Gallee, M., Miles, L. M., Le, M., Zhang, X., Ensina, L. F., Netchiporouk, E. & Ben-Shoshan, M. (2022). Cold urticaria in a pediatric cohort: Clinical characteristics, management, and natural history. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, vol. 33, p. e13751.
  6. Conte, S., Ghazawi, F. M., Le, M., Nedjar, H., Alakel, A., Lagacé, F., Mukovozov, I. M., Cyr, J., Mourad, A., Miller, W. H., Claveau, J., Salopek, T. G., Netchiporouk, E., Gniadecki, R., Sasseville, D., Rahme, E. & Litvinov, I. V. (2022). Population-Based Study Detailing Cutaneous Melanoma Incidence and Mortality Trends in Canada. Frontiers in medicine, vol. 9, p. 830254.
  7. Gabrielli, S., Mule, P., Prosty, C., Gooding, G., Le, M., Zhang, L., Netchiporouk, E., Baum, S., Greenberger, S., Ensina, L. F., Lovett, A., Zhang, X. & Ben-Shoshan, M. (2022). Validation of UAS7 among Children with Chronic Spontaneous Urticaria. The journal of allergy and clinical immunology. In practice.
  8. Conte, S., Lagacé, F., Netchiporouk, E., Sasseville, D. & Litvinov, I. V. (2022). Common Personal Care Products Contaminated With Benzene, a Known Human Carcinogen, Identified Recently. Journal of cutaneous medicine and surgery, p. 12034754221083977.
  9. Zhang, L., Le, M., Gabrielli, S., Netchiporouk, E., Gooding, G., Shand, G., Baum, S., Greenberger, S., Ensina, L. F., Jafarian, F., Zhang, X. & Ben-Shoshan, M. (2022). Biomarkers associated with chronic spontaneous urticaria severity in 108 children. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, vol. 33, p. e13727.
  10. Le, M., Zhang, L., Gabrielli, S., Prosty, C., Miles, L. M., Netchiporouk, E., Baum, S., Greenberger, S., Ensina, L. F., Jafarian, F., Zhang, X. & Ben-Shoshan, M. (2022). Increased prevalence of autoimmune diseases in children with chronic spontaneous urticaria. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, vol. 33, p. e13736.
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See also

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Moshe
Ben-Shoshan


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Carolyn
Jack


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Waqqas
Afif


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