Lab Information
Todd Lee (MD)
ScientistClinical Research Unit
Department of Medicine (McGill)
https://www.drtoddlee.com/
Keywords
Quality improvement • patient safety • high value healthcare • antibiotic stewardship • polypharmacyResearch Interests
My research focuses on conducting randomized clinical trials designed to improve the treatment of infectious diseases (e.g., C. difficile, COVID-19, S. aureus, Gram-Negative infections) and to innovate in the domains of care of complex hospitalized patients, care of older adults with polypharmacy, and stewardship of healthcare resources (e.g., testing, medications).Team Members
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Latest Publications
- Spellberg, B., Wald-Dickler, N., Holtom, P., Meyer-Sautter, P., Camp, A., Diaz, A. D., Buhamad, R., Vazquez, A. S. M., Aguirre-Garcia, G. M., Stanton, M., Butler-Wu, S. M., Chiu, I., Ergenc, Z., Bhoojhawon, G., Murri, R., Maraolo, A. E., Cabanilla, G., Riccardi, N., Tshisevhe, V., Behenna, C., Williams, K. S., Kufel, W. D., Wojciaczyk, N., Pimentel, B. V., Muyidi, A., Costa, R. P., Motta, F., Bortolussi-Courval, É., Lee, T. C., McDonald, E., Ghanem, B. & Nelson, Z. (2025). Static vs. cidal: it's not complex; it's simply incorrect. Antimicrobial agents and chemotherapy, p. e0051325.
- Lasry, D., Lee, T. C., Paquette, K., Demir, K., Yansouni, C., Sweet, D., Cheng, M. P. & Lawandi, A. (2024). Canadian Antibiotic Prescribing for Sepsis (CAPS) Study: A Post Hoc Analysis of the FABLED Cohort Study. Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada, vol. 9, p. 239-248.
- Lee, T. C., Albuquerque, A. M., Lawandi, A., Prosty, C. J., Kotani, Y., Landoni, G. & McDonald, E. G. (2025). Systemic Corticosteroids Continue to Reduce Mortality in Severe Community-Acquired Pneumonia: An Updated Meta-Analysis. Journal of general internal medicine.
- Phillips, M. C., Davar, K., Freling, S., Tong, S. Y. C., Lee, T. C., McDonald, E. G., Nielsen, T. B., Wald-Dickler, N., Mena Lora, A. J., Lee, R. A., Hamilton, F., Musher, D. M., Costa, R. P. L., Ghanem, B., Baden, R. & Spellberg, B. (2025). Practicing With Intent: How to Teach an Old Dogma New Tricks. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
- Hamilton, F., Lee, T. C., Davey Smith, G., Hartwig, F. P. & Butler-Laporte, G. (2025). Does piperacillin-tazobactam increase mortality risk compared to cefepime? Collider bias and the importance of assumptions in instrumental variable analyses. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
- Persaud, N., Workentin, A., Rizvi, A., Pierson, T., Bortolussi-Courval, É., Liu, K., Bennett, A., Shaver, N., Skidmore, B., Vyas, N., Pap, R., Almoli, F., Lee, T. C., Sirois, C., McCracken, R. K., Papillon-Ferland, L. & McDonald, E. G. (2025). Interventions to Address Potentially Inappropriate Prescribing for Older Primary Care Patients: A Systematic Review and Meta-Analysis. JAMA network open, vol. 8, p. e2517965.
- Mellett, M., Lawandi, A., Caya, C., Lee, T. C., Babiker, A., Papenburg, J., Yansouni, C. P. & Cheng, M. P. (2025). Antibiotic synergy against Staphylococcus aureus: a systematic review and meta-analysis. Antimicrobial agents and chemotherapy, p. e0119924.
- Darwish, I., de Varennes, B., Fiset, P. O., Camilleri-Broët, S., Lash, V., Cantarovich, M., Lee, T. C. & Costiniuk, C. T. (2025). A renal transplant recipient with a pulmonic valve mass. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology, p. 107745.
- Chen, G. S., Lee, T., Tsang, J. L. Y., Binnie, A., McCarthy, A., Cowan, J., Archambault, P., Lellouche, F., Turgeon, A. F., Yoon, J., Lamontagne, F., McGeer, A., Douglas, J., Daley, P., Fowler, R., Maslove, D. M., Winston, B. W., Lee, T. C., Tran, K. C., Cheng, M. P., Vinh, D. C., Boyd, J. H., Walley, K. R., Singer, J., Marshall, J. C., Russell, J. A. & Community-Acquired Pneumonia: Toward InnoVAtive Treatment (CAPTIVATE) Investigators (2025). Machine Learning Accurately Predicts Need for Critical Care Support in Patients Admitted to Hospital for Community-Acquired Pneumonia. Critical care explorations, vol. 7, p. e1262.
- McDonald, E. G., Estey, J. L., Davenport, C., Bortolussi-Courval, É., Gaudet, J., Wilson Registe, P. P., Lee, T. C. & Goodine, C. (2025). Electronic Decision Support for Deprescribing in Older Adults Living in Long-Term Care: A Stepped-Wedge Cluster Randomized Trial. JAMA network open, vol. 8, p. e2512931.
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