Lab Information
Todd Lee (MD)
ScientistClinical Research Unit
Department of Medicine (McGill)
Research Profile
https://www.drtoddlee.com/
Keywords
Quality improvement • patient safety • high value healthcare • antibiotic stewardship • polypharmacyResearch Interests
My research focuses on conducting randomized clinical trials designed to improve the treatment of infectious diseases (e.g., C. difficile, COVID-19, S. aureus, Gram-Negative infections) and to innovate in the domains of care of complex hospitalized patients, care of older adults with polypharmacy, and stewardship of healthcare resources (e.g., testing, medications).Team Members
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Latest Publications
- Ong, S. W. X., Pinto, R., Rishu, A., Tong, S. Y. C., Commons, R. J., Conly, J. M., Evans, G. A., Fralick, M., Kandel, C., Lagacé-Wiens, P. R. S., Lee, T. C., Lother, S. A., MacFadden, D. R., Marshall, J. C., Martel-Laferrière, V., Mayette, M., McDonald, E. G., Neary, J. D., Prazak, J., Raby, E., Regli, A., Rogers, B. A., Smith, S., Taggart, L. R., Wang, H. T., Wuerz, T., Yahav, D., Young, P. J., Fowler, R. A., Daneman, N. & BALANCE trial consortium (2025). Identifying heterogeneity of treatment effect for antibiotic duration in bloodstream infection: an exploratory post-hoc analysis of the BALANCE randomised clinical trial. EClinicalMedicine, vol. 83, p. 103195.
- Fresilli, S., Labanca, R., Turi, S., Casuale, V., Vietri, S., Lombardi, G., Covello, R. D., Lee, T. C., Landoni, G., Greco, M. & RIPC group (2025). Remote ischaemic preconditioning and survival in noncardiac surgery: a meta-analysis of randomised trials. British journal of anaesthesia, vol. 134, p. 1373-1384.
- Sohani, Z. N., Lieu, A., Semret, M., Cheng, M. P., Simic, N., Bamba, R., Patel, M., Lawandi, A. & Lee, T. C. (2025). Comparison of ciprofloxacin and aminoglycoside susceptibility testing for ceftriaxone non-susceptible Enterobacterales by disk diffusion and VITEK 2 vs. broth microdilution using updated Clinical and Laboratory Standards Institute breakpoints. BMC microbiology, vol. 25, p. 175.
- Lee, J. J., Bortolussi-Courval, É., Filosa, E., Rej, S., Godard-Sebillote, C., Tamblyn, R., Lee, T. C. & McDonald, E. G. (2025). Criteria to Report Adverse Drug Withdrawal Events in Clinical Trials: A Systematic Review. Journal of the American Geriatrics Society.
- Desormeau, B., Huang, A., Downar, J., Wu, P. E., Bortolussi-Courval, E., Ross, S. B., Battu, K., Papillon-Ferland, L., McAlister, F. A., Elsayed, S., Wilson, M. G., Cavalcanti, R. B., McDonald, E. G. & Lee, T. C. (2025). Prescribing Patterns and Impact of Sedatives in Hospitalized Older Adults: A Secondary Analysis of the MedSafer Study. Journal of the American Geriatrics Society.
- Lee, T. C., Prosty, C. J., Fralick, M., Huttner, A., McDonald, E. G., Molina, J., Paul, M., Pinto, R., Rishu, A., von Dach, E., Yahav, D., Fowler, R. & Daneman, N. (2025). Seven vs Fourteen Days of Antibiotics for Gram-Negative Bloodstream Infection: A Systematic Review and Noninferiority Meta-Analysis. JAMA network open, vol. 8, p. e251421.
- Prosty, C., Katergi, K., Papenburg, J., Lawandi, A., Lee, T. C., Shi, H., Burnham, P., Swem, L., Routy, B., Yansouni, C. P. & Cheng, M. P. (2024). Causal role of the gut microbiome in certain human diseases: a narrative review. eGastroenterology, vol. 2, p. e100086.
- Mahar, R. K., McGlothlin, A., Dymock, M., Barina, L., Bonten, M., Bowen, A., Cheng, M. P., Daneman, N., Goodman, A. L., Lee, T. C., Lewis, R. J., Lumley, T., McLean, A. R. D., McQuilten, Z., Mora, J., Paterson, D. L., Price, D. J., Roberts, J., Snelling, T., Tverring, J., Webb, S. A., Yahav, D., Davis, J. S., Tong, S. Y. C., Marsh, J. A. & SNAP Global Trial Steering Committee (2025). Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial. Trials, vol. 26, p. 49.
- Spellberg, B., Gilbert, D. N., Baym, M., Bearman, G., Boyles, T., Casadevall, A., Forrest, G. N., Freling, S., Ghanem, B., Hamilton, F., Luna, B., Moore, J., Musher, D. M., Nielsen, T. B., Nori, P., Phillips, M. C., Pirofski, L.-A., Shorr, A. F., Tong, S. Y. C., Lee, T. C. & McDonald, E. G. (2025). Sustainable solutions to the continuous threat of antimicrobial resistance. Health affairs scholar, vol. 3, p. qxaf012.
- Prosty, C., Le, M., Lu, Y., Khoury, L., Cormier, M., Cheng, M. P., Fowler, R., Murthy, S., Tsang, J. L., Lejtenyi, D., Ben-Shoshan, M., Rahme, E., Golchi, S., Dendukuri, N., Lee, T. C. & Netchiporouk, E. (2024). Effect of omalizumab on inflammatory markers in COVID-19: an exploratory analysis of the COVID-19 immunologic antiviral therapy with omalizumab (CIAO) trial. Frontiers in medicine, vol. 11, p. 1437322.
See also
