Lab Information

Moshe Ben-Shoshan (MD)

Scientist
Centre for Outcomes Research and Evaluation
Department of Pediatrics (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 20%
 Epidemiology: 80%
 Evaluation: 0%
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Keywords

Food allergy • anaphylaxis • immunodeficiency • chronic urticaria

Research Interests

My research focuses on the prevalence and potential determinants of food allergies and anaphylaxis (severe allergic reactions) in children. In addition, I have established a registry aiming to assess triggers and management of different forms of chronic urticaria, or hives. I also conduct research on primary immunodeficiencies, exploring the ability of children's immune systems to fight infectious disease. In collaboration with Dr. Ann Clarke at the Montreal General Hospital of the MUHC, I conducted the first nationwide Canadian study to determine the prevalence of severe food allergies. The results indicate disparities between perceived and confirmed food allergy that might contribute to the wide range of published prevalence estimates. In recent years I have led the first Canada-wide anaphylaxis registry exploring the societal burden, triggers, management and natural history of anaphylaxis in Canadians.


Team Members

Name Position

Latest Publications

  1. Mulé, A., Prattico, C., Al Ali, A., Mulé, P. & Ben-Shoshan, M. (2023). Diagnostic and Management Strategies of Food Protein-Induced Enterocolitis Syndrome: Current Perspectives. Pediatric health, medicine and therapeutics, vol. 14, p. 337-345.
  2. Zhu, C. K., Nguyen, A., Prosty, C., Gabrielli, S., Mulé, P., Netchiporouk, E., Le, M., Zhang, X., Shand, G., Baum, S., Hakroush, R., Greenberger, S., Ollech, A., Miedzybrodzki, B. & Ben-Shoshan, M. (2023). Safety of COVID-19 mRNA vaccination and effects of SARS-CoV-2 infection in children and adults with mast cell disorders. Clinical and experimental medicine.
  3. Sillcox, C., Gabrielli, S., O'Keefe, A., McCusker, C., Abrams, E. M., Eiwegger, T., Atkinson, A., Kim, V., Copaescu, A.-M., Ben-Shoshan, M., Sillcox, C., Gabrielli, S., O'Keefe, A., McCusker, C., Abrams, E. M., Eiwegger, T., Atkinson, A., Kim, V., Copaescu, A.-M. & Ben-Shoshan, M. (2023). Assessing Pediatric Cephalosporin Allergic Reactions Through Direct Graded Oral Challenges. The journal of allergy and clinical immunology. In practice.
  4. Stehlin, F., Khoudja, R. Y., Al-Otaibi, I., ALMuhizi, F., Fein, M., Gilbert, L., Tsoukas, C., Ben-Shoshan, M., Copaescu, A.-M. & Clarisse Isabwe, G. A. (2023). COVID-19 booster vaccine acceptance following allergy evaluation in individuals with allergies. The journal of allergy and clinical immunology. In practice.
  5. Colli, L. D., Ali, A. A., Gabrielli, S., Colli, M. D., Mule, P., Lawson, B., Clarke, A. E., Morris, J., Gravel, J., Lim, R., Chan, E. S., Goldman, R. D., O'Keefe, A., Gerdts, J., Chu, D. K., Upton, J., Hochstadter, E., Bretholz, A., McCusker, C., Zhang, X., Benor, S., Simons, E., Abrams, E. M., Protudjer, J. L. P. & Ben-Shoshan, M. (2023). Managing Anaphylaxis - Epinephrine, Antihistamines, and Corticosteroids: Over 10 years of C-CARE Registry Data. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, vol. 131, p. 752-758.e1.
  6. Batac, A. L. R., Merrill, K. A., Golding, M. A., Abrams, E. M., Bégin, P., Ben-Shoshan, M., Ladouceur, E., Roos, L. E., Protudjer, V. & Protudjer, J. L. P. (2023). A qualitative investigation into vaccine hesitancy and confidence amongst people managing allergy. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, vol. 131, p. 775-777.
  7. Bhamra, M., Harbottle, Z., Golding, M. A., Ben-Shoshan, M., Roos, L. E., Abrams, E. M., Penner, S. J., St-Vincent, J.-A. & Protudjer, J. L. (2023). Parental perceptions of a novel subsidy program to address the financial burden of milk allergy: a qualitative study. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, vol. 19, p. 65.
  8. Santos, M. J. L., Merrill, K. A., Ben-Shoshan, M., Gerdts, J. D., Giesbrecht, D., Lavine, E., Prentice, S., Upton, J. & Protudjer, J. L. P. (2023). Food Allergy Education and Management in Early Learning and Childcare Centres: A Scoping Review on Current Practices and Gaps. Children (Basel, Switzerland), vol. 10.
  9. Staubach, P., Alvaro-Lozano, M., Sekerel, B. E., Maurer, M., Ben-Shoshan, M., Porter, M., Hua, E., Ji, Y., Burciu, A., Savelieva, M., Severin, T., Drollmann, A. & Bienczak, A. (2023). Ligelizumab in adolescents with chronic spontaneous urticaria: Results of a dedicated phase 2b randomized clinical trial supported with pharmacometric analysis. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, vol. 34, p. e13982.
  10. Abrams, E. M., Ben-Shoshan, M., Protudjer, J. L. P., Lavine, E. & Chan, E. S. (2023). Early introduction is not enough: CSACI statement on the importance of ongoing regular ingestion as a means of food allergy prevention. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, vol. 19, p. 63.
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