Lab Information

Brian Ward (MD)

Senior Scientist
Centre for Translational Biology
Department of Medicine (McGill)

Research Profile

 Fundamental: 75%
 Clinical: 25%
 Epidemiology: 0%
 Evaluation: 0%
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Keywords

Vaccines • respiratory viruses • international health • parasitology • diagnostics

Research Interests

My research focuses on: the development and evaluation of novel virus-like particle vaccines (eg: influenza, measles) in both young and elderly subjects, international health issues with a particular focus on factors that influence HIV transmission, virus-nutritional interactions, and the development of new diagnostic tests for parasitic diseases. My laboratory sits at the junction between infectious diseases clinic and the basic science laboratory. Projects can start at either end of this spectrum and move from 'bed to the bench-top' or from 'bench-top to the bed'. Most of the basic work is carried out in Montreal with satellite facilities in Peru and Zimbabwe. Human vaccine studies are conducted at the MUHC Vaccine Study Centre in Pierrefonds, QC.


Team Members

Name Position

Latest Publications

  1. Hager, K. J., Pérez Marc, G., Gobeil, P., Diaz, R. S., Heizer, G., Llapur, C., Makarkov, A. I., Vasconcellos, E., Pillet, S., Riera, F., Saxena, P., Geller Wolff, P., Bhutada, K., Wallace, G., Aazami, H., Jones, C. E., Polack, F. P., Ferrara, L., Atkins, J., Boulay, I., Dhaliwall, J., Charland, N., Couture, M. M. J., Jiang-Wright, J., Landry, N., Lapointe, S., Lorin, A., Mahmood, A., Moulton, L. H., Pahmer, E., Parent, J., Séguin, A., Tran, L., Breuer, T., Ceregido, M.-A., Koutsoukos, M., Roman, F., Namba, J., D'Aoust, M.-A., Trepanier, S., Kimura, Y., Ward, B. J. & CoVLP Study Team (2022). Efficacy and Safety of a Recombinant Plant-Based Adjuvanted Covid-19 Vaccine. The New England journal of medicine.
  2. Cross, A. H., Delgado, S., Habek, M., Davydovskaya, M., Ward, B. J., Cree, B. A. C., Totolyan, N., Pingili, R., Mancione, L., Hu, X., Sullivan, R., Su, W., Zielman, R., Gupta, A. D., Montalban, X. & Winthrop, K. (2022). Correction to: COVID-19 Outcomes and Vaccination in People with Relapsing Multiple Sclerosis Treated with Ofatumumab. Neurology and therapy, vol. 11, p. 759-762.
  3. Hendin, H. E., Lavoie, P.-O., Gravett, J. M., Pillet, S., Saxena, P., Landry, N., D'Aoust, M.-A. & Ward, B. J. (2022). Elimination of receptor binding by influenza hemagglutinin improves vaccine-induced immunity. NPJ vaccines, vol. 7, p. 42.
  4. Del Poeta, M., Ward, B. J., Greenberg, B., Hemmer, B., Cree, B. A. C., Komatireddy, S., Mishra, J., Sullivan, R., Kilaru, A., Moore, A., Hach, T. & Berger, J. R. (2022). Cryptococcal Meningitis Reported With Fingolimod Treatment: Case Series. Neurology(R) neuroimmunology & neuroinflammation, vol. 9.
  5. Cross, A. H., Delgado, S., Habek, M., Davydovskaya, M., Ward, B. J., Cree, B. A. C., Totolyan, N., Pingili, R., Mancione, L., Hu, X., Sullivan, R., Su, W., Zielman, R., Gupta, A. D., Montalban, X. & Winthrop, K. (2022). COVID-19 Outcomes and Vaccination in People with Relapsing Multiple Sclerosis Treated with Ofatumumab. Neurology and therapy, vol. 11, p. 741-758.
  6. Kane, P. B., Moyer, H., MacPherson, A., Papenburg, J., Ward, B. J., Broomell, S. B. & Kimmleman, J. (2022). Relationship between lay and expert perceptions of COVID-19 vaccine development timelines in Canada and USA. PloS one, vol. 17, p. e0262740.
  7. Pillet, S., Arunachalam, P. S., Andreani, G., Golden, N., Fontenot, J., Aye, P. P., Röltgen, K., Lehmicke, G., Gobeil, P., Dubé, C., Trépanier, S., Charland, N., D'Aoust, M.-A., Russell-Lodrigue, K., Monjure, C., Blair, R. V., Boyd, S. D., Bohm, R. P., Rappaport, J., Villinger, F., Landry, N., Pulendran, B. & Ward, B. J. (2022). Safety, immunogenicity, and protection provided by unadjuvanted and adjuvanted formulations of a recombinant plant-derived virus-like particle vaccine candidate for COVID-19 in nonhuman primates. Cellular & molecular immunology, vol. 19, p. 222-233.
  8. Sullivan, R., Kilaru, A., Hemmer, B., Campbell Cree, B. A., Greenberg, B. M., Kundu, U., Hach, T., DeLasHeras, V., Ward, B. J. & Berger, J. (2021). COVID-19 Infection in Fingolimod- or Siponimod-Treated Patients: Case Series. Neurology(R) neuroimmunology & neuroinflammation, vol. 9.
  9. Dubé, C., Paris-Robidas, S., Primakova, I., Destexhe, E., Ward, B. J., Landry, N. & Trépanier, S. (2021). Lack of Effects on Female Fertility or Pre- and Postnatal Development of Offspring in Rats after Exposure to AS03-adjuvanted Recombinant Plant-Derived Virus-Like Particle Vaccine Candidate for COVID-19. Reproductive toxicology (Elmsford, N.Y.), vol. 107, p. 69-80.
  10. Machado, M. A. A., Moura, C. S., Abrahamowicz, M., Ward, B. J., Pilote, L. & Bernatsky, S. (2021). Relative effectiveness of influenza vaccines in elderly persons in the United States, 2012/2013-2017/2018 seasons. NPJ vaccines, vol. 6, p. 108.
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