Lab Information

Sasha Bernatsky (MD/PhD)

Senior Scientist
Centre for Outcomes Research and Evaluation
Department of Medicine (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 0%
 Epidemiology: 100%
 Evaluation: 0%
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Outcomes in rheumatic diseases • pharmacoepidemiology • air pollution’s effects on health • systemic lupus erythematosus

Research Interests

Dr. Sasha Bernatsky is a James McGill Professor of Medicine at McGill University (divisions of rheumatology and clinical epidemiology), and senior scientist within the Centre for Health Outcomes Research at the Research Institute of the McGill University Health Centre, the Infectious Diseases and Immunity in Global Health Program, and McGill’s Epidemiology and Biostatistics Department. She is nominated PI of CAN-AIM (CAnadian Network for Advanced Interdisciplinary Methods for comparative effectiveness research), a pan-Canadian group funded by the Drug Safety and Effectiveness Network (DSEN), a collaboration between CIHR, Health Canada, and other stakeholders. Working with Health Canada’s Marketed Health Products Directorate and other regulators, CAN-AIM studies high-priority drug safety and effectiveness topics, making essential contributions to Canada’s research capacity. She also mentors within CIHR’s Drug Safety and Effectiveness Cross-Disciplinary Training Program, preparing future leaders in this field.

Working with the SLE International Collaborating Clinics and the Canadian Network for Improved Outcomes in SLE, Dr. Bernatsky leads international initiatives including assessments of malignancy in SLE, and personalizing approaches to hydroxychloroquine therapy. She co-founded several collaborative networks, including the Canadian Rheumatology Administrative Data Network (CANRAD), focussing on optimal use of administrative data for research and surveillance. Studying rheumatic disease patterns with administrative data from across Canada, she contributed greatly to Public Health Agency of Canada’s work on rheumatic disease case validation, and helped the Canadian Institute for Health Information refine case definitions for federal research and surveillance. Affiliated with the McGill Environmental Epidemiology Research Group and the Canadian Urban Environmental Health Research Consortium, she pioneered studies of air pollution and systemic autoimmune rheumatic diseases.

Team Members

Name Position

Latest Publications

  1. Zhao, N., Smargiassi, A., Jean, S., Gamache, P., Laouan-Sidi, E.-A., Chen, H., Goldberg, M. S. & Bernatsky, S. (2022). Long-term exposure to fine particulate matter and ozone and the onset of systemic autoimmune rheumatic diseases: an open cohort study in Quebec, Canada. Arthritis research & therapy, vol. 24, p. 151.
  2. Quan, J., Ma, C., Panaccione, R., Hracs, L., Sharifi, N., Herauf, M., Makovinović, A., Coward, S., Windsor, J. W., Caplan, L., Ingram, R. J. M., Kanji, J. N., Tipples, G., Holodinsky, J. K., Bernstein, C. N., Mahoney, D. J., Bernatsky, S., Benchimol, E. I., Kaplan, G. G. & STOP COVID-19 in IBD Research Group (2022). Serological responses to three doses of SARS-CoV-2 vaccination in inflammatory bowel disease. Gut.
  3. Orozco, T., Feldman, D. E., Bernatsky, S., Légaré, J., Perreault, K., Tawiah, A. K., Zummer, M. & Hudon, A. (2022). Evaluating a new referral pathway from physical therapists to rheumatologists: A qualitative study. Journal of interprofessional care, p. 1-9.
  4. Widdifield, J., Kwong, J. C., Chen, S., Eder, L., Benchimol, E. I., Kaplan, G. G., Hitchon, C., Aviña-Zubieta, J. A., Lacaille, D., Chung, H. & Bernatsky, S. (2022). Vaccine effectiveness against SARS-CoV-2 infection and severe outcomes among individuals with immune-mediated inflammatory diseases tested between March 1 and Nov 22, 2021, in Ontario, Canada: a population-based analysis. The Lancet. Rheumatology, vol. 4, p. e430-e440.
  5. Choi, M. Y., Clarke, A. E., Urowitz, M., Hanly, J., St-Pierre, Y., Gordon, C., Bae, S.-C., Romero-Diaz, J., Sanchez-Guerrero, J., Bernatsky, S., Wallace, D. J., Isenberg, D., Rahman, A., Merrill, J. T., Fortin, P. R., Gladman, D. D., Bruce, I. N., Petri, M., Ginzler, E. M., Dooley, M. A., Ramsey-Goldman, R., Manzi, S., Jönsen, A., Alarcón, G. S., van Vollenhoven, R. F., Aranow, C., Mackay, M., Ruiz-Irastorza, G., Lim, S., Inanc, M., Kalunian, K., Jacobsen, S., Peschken, C., Kamen, D. L., Askanase, A., Buyon, J. P., Costenbader, K. H. & Fritzler, M. J. (2022). Longitudinal analysis of ANA in the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort. Annals of the rheumatic diseases.
  6. Bérard, A., Gorgui, J., Tchuente, V., Lacasse, A., Gomez, Y.-H., Côté, S., King, S., Muanda, F., Mufike, Y., Boucoiran, I., Nuyt, A. M., Quach, C., Ferreira, E., Kaul, P., Winquist, B., O'Donnell, K. J., Eltonsy, S., Chateau, D., Zhao, J.-P., Hanley, G., Oberlander, T., Kassai, B., Mainbourg, S., Bernatsky, S., Vinet, É., Brodeur-Doucet, A., Demers, J., Richebé, P. & Zaphiratos, V. (2022). The COVID-19 Pandemic Impacted Maternal Mental Health Differently Depending on Pregnancy Status and Trimester of Gestation. International journal of environmental research and public health, vol. 19.
  7. Kuenzig, M. E., Widdifield, J., Bernatsky, S., Kaplan, G. G. & Benchimol, E. I. (2022). Uptake of third doses of SARS-CoV-2 vaccines among people with inflammatory bowel disease in Ontario, Canada. The lancet. Gastroenterology & hepatology, vol. 7, p. 288-289.
  8. Barbacki, A., Rached-d'Astous, N., Pineau, C. A., Vinet, E., Grenier, L.-P., Kalache, F., Fallavollita, S., Lukusa, L. & Bernatsky, S. (2022). Clinical Significance of Raynaud Phenomenon in Systemic Lupus Erythematosus. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, vol. 28, p. e488-e490.
  9. Ugarte-Gil, M. F., Alarcón, G. S., Izadi, Z., Duarte-García, A., Reátegui-Sokolova, C., Clarke, A. E., Wise, L., Pons-Estel, G. J., Santos, M. J., Bernatsky, S., Ribeiro, S. L. E., Al Emadi, S., Sparks, J. A., Hsu, T.-Y., Patel, N. J., Gilbert, E. L., Valenzuela-Almada, M. O., Jönsen, A., Landolfi, G., Fredi, M., Goulenok, T., Devaux, M., Mariette, X., Queyrel, V., Romão, V. C., Sequeira, G., Hasseli, R., Hoyer, B., Voll, R. E., Specker, C., Baez, R., Castro-Coello, V., Maldonado Ficco, H., Reis Neto, E. T., Ferreira, G. A. A., Monticielo, O. A. A., Sirotich, E., Liew, J., Hausmann, J., Sufka, P., Grainger, R., Bhana, S., Costello, W., Wallace, Z. S., Jacobsohn, L., Taylor, T., Ja, C., Strangfeld, A., Mateus, E. F., Hyrich, K. L., Carmona, L., Lawson-Tovey, S., Kearsley-Fleet, L., Schäfer, M., Machado, P. M., Robinson, P. C., Gianfrancesco, M. & Yazdany, J. (2022). Characteristics associated with poor COVID-19 outcomes in individuals with systemic lupus erythematosus: data from the COVID-19 Global Rheumatology Alliance. Annals of the rheumatic diseases.
  10. Woo, J. M. P., Parks, C. G., Jacobsen, S., Costenbader, K. H. & Bernatsky, S. (2022). The role of environmental exposures and gene-environment interactions in the etiology of systemic lupus erythematous. Journal of internal medicine, vol. 291, p. 755-778.
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