Information sur le laboratoire
Todd Lee (M.D.)
ScientifiqueUnité de recherche clinique
Département de médecine (McGill)
Profil de recherche
https://www.drtoddlee.com/
Mots-clés
Amélioration de la qualité • gestion de l'utilisation des antimicrobiens • résistance aux antibiotiques • essaies cliniques • polypharmacieIntérêts de recherche
Mes recherches portent sur la réalisation d'essais cliniques randomisés visant à améliorer le traitement des maladies infectieuses (par exemple, C. difficile, COVID-19, S. aureus, infections à Gram négatif) et à innover dans les domaines des soins de patients hospitalisés complexes, des soins des adultes plus âgés atteints de polypharmacie, et de la gérance des ressources en soins de santé (par exemple, les tests et les médicaments).Membre de l'équipe
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Dernières publications
- Aw, M., Lee, T. C., Mendel, A. & Colmegna, I. (2025). Parvovirus B19-Associated Large-Vessel Vasculitis in an Immunocompromised Patient. The Journal of rheumatology.
- Turner, N. A., Hamasaki, T., Doernberg, S. B., Lodise, T. P., King, H. A., Ghazaryan, V., Cosgrove, S. E., Jenkins, T. C., Liu, C., Sharma, S., Zaharoff, S., Wahid, L., Renard, V. J., Cook, P., Raad, I., Hachem, R., Chaftari, A.-M., Sims, M., DeMarco, C., Miller, L. G., McCarthy, M. W., Morse, C. G., Lucasti, C., Forrest, G. N., Cherabuddi, K., Polk, C., Fazili, T., Rupp, M. E., Thompson, G. R., Kim, K., Strnad, L., Schnee, A. E., McKinnell, J. A., Ramesh, M., Silveira, F. P., McCarty, T. P., Lee, T. C., McDonald, E. G., Paolino, K., Wiegand, K., Wall, A., Riccobene, T., Patel, R., Rappo, U., Evans, S., Chambers, H. F., Fowler, V. G., Holland, T. L. & Antibacterial Resistance Leadership Group (2025). Dalbavancin for Treatment of Staphylococcus aureus Bacteremia: The DOTS Randomized Clinical Trial. JAMA.
- Prosty, C., Noutsios, D., Dubé, L.-R., Baden, R., Davar, K., Freling, S., Bhuket, T., Yee, H. F., Spellberg, B., McDonald, E. G. & Lee, T. C. (2025). Prophylactic Antibiotics for Upper Gastrointestinal Bleeding in Patients With Cirrhosis: A Systematic Review and Bayesian Meta-Analysis. JAMA internal medicine.
- Hosseini, B., Condon, A., da Costa, B. R., Daley, P., Greiver, M., Jüni, P., Lee, T. C., McBrien, K., McDonald, E. G., Murthy, S., Selby, P., Andrew, M., Aubrey-Bassler, K., Barber, D., Barrett, B., Butler, C. C., Crampton, N., Dahrouge, S., Damji, A., Fowler, R., Garies, S., Hudon, C., Hulme, J., Isenor, J., Jenkins, D. J. A., Lall, R., LeBlanc, A., Leong, C., Little, P., Lofters, A., Logsetty, S., Lother, S., Lussier, M.-T., Maclaren, L., Mangin, D., Marshall, E. G., Marshall, J. C., McCracken, R., Moineddin, R., Orava, B., Paquette, J.-S., Park, J. J. H., Persaud, N., Rac, V. E., Ramsden, V. R., Rayner, J., Sanchez-Ramirez, D. C., Saxinger, L., Shi, H., Singer, A., Spiwak, R., Srivastava, A., Sud, A., Tarride, J.-E., Telner, D., Upshur, R. E. G., Walji, S., Walsh, R., Wilchesky, M., Wong, S. T., Wood, B., Zarychanski, R., Zelek, B., Keynan, Y., Piszczek, J., Warshafsky, D. & Pinto, A. D. (2025). Canadian Adaptive Platform Trial of Treatments for COVID in Community Settings (CanTreatCOVID): protocol for a randomised controlled adaptive platform trial of treatments for acute SARS-CoV-2 infection in community settings. BMJ open, vol. 15, p. e097134.
- Lee, J. J., Lee, T. C. & McDonald, E. G. (2025). Response to "Broadening the Lens on Reporting to Include Older Adults' Emotional Responses During Deprescribing Trials". Journal of the American Geriatrics Society.
- Spellberg, B., Wald-Dickler, N., Holtom, P., Meyer-Sautter, P., Camp, A., Diaz, A. D., Buhamad, R., Vazquez, A. S. M., Aguirre-Garcia, G. M., Stanton, M., Butler-Wu, S. M., Chiu, I., Ergenc, Z., Bhoojhawon, G., Murri, R., Maraolo, A. E., Cabanilla, G., Riccardi, N., Tshisevhe, V., Behenna, C., Williams, K. S., Kufel, W. D., Wojciaczyk, N., Pimentel, B. V., Muyidi, A., Costa, R. P., Motta, F., Bortolussi-Courval, É., Lee, T. C., McDonald, E., Ghanem, B. & Nelson, Z. (2025). Static vs. cidal: it's not complex; it's simply incorrect. Antimicrobial agents and chemotherapy, p. e0051325.
- Lasry, D., Lee, T. C., Paquette, K., Demir, K., Yansouni, C., Sweet, D., Cheng, M. P. & Lawandi, A. (2024). Canadian Antibiotic Prescribing for Sepsis (CAPS) Study: A Post Hoc Analysis of the FABLED Cohort Study. Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada, vol. 9, p. 239-248.
- Lee, T. C., Albuquerque, A. M., Lawandi, A., Prosty, C. J., Kotani, Y., Landoni, G. & McDonald, E. G. (2025). Systemic Corticosteroids Continue to Reduce Mortality in Severe Community-Acquired Pneumonia: An Updated Meta-Analysis. Journal of general internal medicine.
- Phillips, M. C., Davar, K., Freling, S., Tong, S. Y. C., Lee, T. C., McDonald, E. G., Nielsen, T. B., Wald-Dickler, N., Mena Lora, A. J., Lee, R. A., Hamilton, F., Musher, D. M., Costa, R. P. L., Ghanem, B., Baden, R. & Spellberg, B. (2025). Practicing With Intent: How to Teach an Old Dogma New Tricks. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
- Hamilton, F., Lee, T. C., Davey Smith, G., Hartwig, F. P. & Butler-Laporte, G. (2025). Does piperacillin-tazobactam increase mortality risk compared to cefepime? Collider bias and the importance of assumptions in instrumental variable analyses. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
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