Information sur le laboratoire
Todd Lee (M.D.)
ScientifiqueUnité de recherche clinique
Département de médecine (McGill)
Profil de recherche
https://www.drtoddlee.com/
Mots-clés
Amélioration de la qualité • gestion de l'utilisation des antimicrobiens • résistance aux antibiotiques • essaies cliniques • polypharmacieIntérêts de recherche
Mes recherches portent sur la réalisation d'essais cliniques randomisés visant à améliorer le traitement des maladies infectieuses (par exemple, C. difficile, COVID-19, S. aureus, infections à Gram négatif) et à innover dans les domaines des soins de patients hospitalisés complexes, des soins des adultes plus âgés atteints de polypharmacie, et de la gérance des ressources en soins de santé (par exemple, les tests et les médicaments).Membre de l'équipe
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Dernières publications
- Fresilli, S., Labanca, R., Turi, S., Casuale, V., Vietri, S., Lombardi, G., Covello, R. D., Lee, T. C., Landoni, G., Greco, M. & RIPC group (2025). Remote ischaemic preconditioning and survival in noncardiac surgery: a meta-analysis of randomised trials. British journal of anaesthesia.
- Sohani, Z. N., Lieu, A., Semret, M., Cheng, M. P., Simic, N., Bamba, R., Patel, M., Lawandi, A. & Lee, T. C. (2025). Comparison of ciprofloxacin and aminoglycoside susceptibility testing for ceftriaxone non-susceptible Enterobacterales by disk diffusion and VITEK 2 vs. broth microdilution using updated Clinical and Laboratory Standards Institute breakpoints. BMC microbiology, vol. 25, p. 175.
- Lee, J. J., Bortolussi-Courval, É., Filosa, E., Rej, S., Godard-Sebillote, C., Tamblyn, R., Lee, T. C. & McDonald, E. G. (2025). Criteria to Report Adverse Drug Withdrawal Events in Clinical Trials: A Systematic Review. Journal of the American Geriatrics Society.
- Desormeau, B., Huang, A., Downar, J., Wu, P. E., Bortolussi-Courval, E., Ross, S. B., Battu, K., Papillon-Ferland, L., McAlister, F. A., Elsayed, S., Wilson, M. G., Cavalcanti, R. B., McDonald, E. G. & Lee, T. C. (2025). Prescribing Patterns and Impact of Sedatives in Hospitalized Older Adults: A Secondary Analysis of the MedSafer Study. Journal of the American Geriatrics Society.
- Lee, T. C., Prosty, C. J., Fralick, M., Huttner, A., McDonald, E. G., Molina, J., Paul, M., Pinto, R., Rishu, A., von Dach, E., Yahav, D., Fowler, R. & Daneman, N. (2025). Seven vs Fourteen Days of Antibiotics for Gram-Negative Bloodstream Infection: A Systematic Review and Noninferiority Meta-Analysis. JAMA network open, vol. 8, p. e251421.
- Prosty, C., Katergi, K., Papenburg, J., Lawandi, A., Lee, T. C., Shi, H., Burnham, P., Swem, L., Routy, B., Yansouni, C. P. & Cheng, M. P. (2024). Causal role of the gut microbiome in certain human diseases: a narrative review. eGastroenterology, vol. 2, p. e100086.
- Mahar, R. K., McGlothlin, A., Dymock, M., Barina, L., Bonten, M., Bowen, A., Cheng, M. P., Daneman, N., Goodman, A. L., Lee, T. C., Lewis, R. J., Lumley, T., McLean, A. R. D., McQuilten, Z., Mora, J., Paterson, D. L., Price, D. J., Roberts, J., Snelling, T., Tverring, J., Webb, S. A., Yahav, D., Davis, J. S., Tong, S. Y. C., Marsh, J. A. & SNAP Global Trial Steering Committee (2025). Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial. Trials, vol. 26, p. 49.
- Spellberg, B., Gilbert, D. N., Baym, M., Bearman, G., Boyles, T., Casadevall, A., Forrest, G. N., Freling, S., Ghanem, B., Hamilton, F., Luna, B., Moore, J., Musher, D. M., Nielsen, T. B., Nori, P., Phillips, M. C., Pirofski, L.-A., Shorr, A. F., Tong, S. Y. C., Lee, T. C. & McDonald, E. G. (2025). Sustainable solutions to the continuous threat of antimicrobial resistance. Health affairs scholar, vol. 3, p. qxaf012.
- Prosty, C., Le, M., Lu, Y., Khoury, L., Cormier, M., Cheng, M. P., Fowler, R., Murthy, S., Tsang, J. L., Lejtenyi, D., Ben-Shoshan, M., Rahme, E., Golchi, S., Dendukuri, N., Lee, T. C. & Netchiporouk, E. (2024). Effect of omalizumab on inflammatory markers in COVID-19: an exploratory analysis of the COVID-19 immunologic antiviral therapy with omalizumab (CIAO) trial. Frontiers in medicine, vol. 11, p. 1437322.
- Haljan, G., Lee, T., McCarthy, A., Cowan, J., Tsang, J., Lelouche, F., Turgeon, A. F., Archambault, P., Lamontagne, F., Fowler, R., Yoon, J., Daley, P., Cheng, M. P., Vinh, D. C., Lee, T. C., Tran, K. C., Winston, B. W., Kong, H. J., Boyd, J. H., Walley, K. R., McGeer, A., Maslove, D. M., Marshall, J. C., Singer, J., Jain, F. & Russell, J. A. (2024). Complex Thrombo-Inflammatory Responses versus Outcomes of Non-COVID-19 Community-Acquired Pneumonia and COVID-19. Journal of innate immunity, vol. 16, p. 529-552.
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