Information sur le laboratoire
Todd Lee (M.D.)
ScientifiqueUnité de recherche clinique
Département de médecine (McGill)
Profil de recherche
https://www.drtoddlee.com/
Mots-clés
Amélioration de la qualité • gestion de l'utilisation des antimicrobiens • résistance aux antibiotiques • essaies cliniques • polypharmacieIntérêts de recherche
Mes recherches portent sur la réalisation d'essais cliniques randomisés visant à améliorer le traitement des maladies infectieuses (par exemple, C. difficile, COVID-19, S. aureus, infections à Gram négatif) et à innover dans les domaines des soins de patients hospitalisés complexes, des soins des adultes plus âgés atteints de polypharmacie, et de la gérance des ressources en soins de santé (par exemple, les tests et les médicaments).Membre de l'équipe
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Dernières publications
- Prosty, C., Katergi, K., Papenburg, J., Lawandi, A., Lee, T. C., Shi, H., Burnham, P., Swem, L., Routy, B., Yansouni, C. P. & Cheng, M. P. (2024). Causal role of the gut microbiome in certain human diseases: a narrative review. eGastroenterology, vol. 2, p. e100086.
- Mahar, R. K., McGlothlin, A., Dymock, M., Barina, L., Bonten, M., Bowen, A., Cheng, M. P., Daneman, N., Goodman, A. L., Lee, T. C., Lewis, R. J., Lumley, T., McLean, A. R. D., McQuilten, Z., Mora, J., Paterson, D. L., Price, D. J., Roberts, J., Snelling, T., Tverring, J., Webb, S. A., Yahav, D., Davis, J. S., Tong, S. Y. C., Marsh, J. A. & SNAP Global Trial Steering Committee (2025). Statistical documentation for multi-disease, multi-domain platform trials: our experience with the Staphylococcus aureus Network Adaptive Platform trial. Trials, vol. 26, p. 49.
- Spellberg, B., Gilbert, D. N., Baym, M., Bearman, G., Boyles, T., Casadevall, A., Forrest, G. N., Freling, S., Ghanem, B., Hamilton, F., Luna, B., Moore, J., Musher, D. M., Nielsen, T. B., Nori, P., Phillips, M. C., Pirofski, L.-A., Shorr, A. F., Tong, S. Y. C., Lee, T. C. & McDonald, E. G. (2025). Sustainable solutions to the continuous threat of antimicrobial resistance. Health affairs scholar, vol. 3, p. qxaf012.
- Prosty, C., Le, M., Lu, Y., Khoury, L., Cormier, M., Cheng, M. P., Fowler, R., Murthy, S., Tsang, J. L., Lejtenyi, D., Ben-Shoshan, M., Rahme, E., Golchi, S., Dendukuri, N., Lee, T. C. & Netchiporouk, E. (2024). Effect of omalizumab on inflammatory markers in COVID-19: an exploratory analysis of the COVID-19 immunologic antiviral therapy with omalizumab (CIAO) trial. Frontiers in medicine, vol. 11, p. 1437322.
- Haljan, G., Lee, T., McCarthy, A., Cowan, J., Tsang, J., Lelouche, F., Turgeon, A. F., Archambault, P., Lamontagne, F., Fowler, R., Yoon, J., Daley, P., Cheng, M. P., Vinh, D. C., Lee, T. C., Tran, K. C., Winston, B. W., Kong, H. J., Boyd, J. H., Walley, K. R., McGeer, A., Maslove, D. M., Marshall, J. C., Singer, J., Jain, F. & Russell, J. A. (2024). Complex Thrombo-Inflammatory Responses versus Outcomes of Non-COVID-19 Community-Acquired Pneumonia and COVID-19. Journal of innate immunity, vol. 16, p. 529-552.
- Widera, E., Lee, T. C. & Prasad, V. (2024). Paxlovid Awareness, Reporting Bias. Health affairs (Project Hope), vol. 43, p. 1733.
- Spellberg, B., Lee, T. C., Ghanem, B. & McDonald, E. G. (2024). Endocarditis Therapy: The Move From Expert Opinion to Evidence. Journal of the American College of Cardiology, vol. 84, p. 2305-2307.
- Sohani, Z. N., Lieu, A., Bamba, R., Patel, M., Paul, M., Yahav, D., McDonald, E. G., Lawandi, A. & Lee, T. C. (2024). Establishing piperacillin-tazobactam susceptibility in ceftriaxone non-susceptible Enterobacterales: comparing disk diffusion, Etest, and VITEK 2 automated MIC measurements vs. broth microdilution. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
- Tsang, J. L. Y., Rego, K., Binnie, A., Lee, T., Mccarthy, A., Cowan, J., Archambault, P., Lellouche, F., Turgeon, A. F., Yoon, J., Lamontagne, F., Mcgeer, A., Douglas, J., Daley, P., Fowler, R., Maslove, D. M., Winston, B. W., Lee, T. C., Tran, K. C., Cheng, M. P., Vinh, D. C., Boyd, J. H., Walley, K. R., Singer, J., Marshall, J. C., Haljan, G., Jain, F., Russell, J. A. & For CAPTIVATE Investigators (2024). Community versus academic hospital community-acquired pneumonia patients: a nested cohort study. Pneumonia (Nathan Qld.), vol. 16, p. 31.
- BALANCE Investigators, for the Canadian Critical Care Trials Group, the Association of Medical Microbiology and Infectious Disease Canada Clinical Research Network, the Australian and New Zealand Intensive Care Society Clinical Trials Group, and the Australasian Society for Infectious Diseases Clinical Research Network, Daneman, N., Rishu, A., Pinto, R., Rogers, B. A., Shehabi, Y., Parke, R., Cook, D., Arabi, Y., Muscedere, J., Reynolds, S., Hall, R., Dwivedi, D. B., McArthur, C., McGuinness, S., Yahav, D., Coburn, B., Geagea, A., Das, P., Shin, P., Detsky, M., Morris, A., Fralick, M., Powis, J. E., Kandel, C., Sligl, W., Bagshaw, S. M., Singhal, N., Belley-Cote, E., Whitlock, R., Khwaja, K., Morpeth, S., Kazemi, A., Williams, A., MacFadden, D. R., McIntyre, L., Tsang, J., Lamontagne, F., Carignan, A., Marshall, J., Friedrich, J. O., Cirone, R., Downing, M., Graham, C., Davis, J., Duan, E., Neary, J., Evans, G., Alraddadi, B., Al Johani, S., Martin, C., Elsayed, S., Ball, I., Lauzier, F., Turgeon, A., Stelfox, H. T., Conly, J., McDonald, E. G., Lee, T. C., Sullivan, R., Grant, J., Kagan, I., Young, P., Lawrence, C., O'Callaghan, K., Eustace, M., Choong, K., Aslanian, P., Buehner, U., Havey, T., Binnie, A., Prazak, J., Reeve, B., Litton, E., Lother, S., Kumar, A., Zarychanski, R., Hoffman, T., Paterson, D., Daley, P., Commons, R. J., Charbonney, E., Naud, J.-F., Roberts, S., Tiruvoipati, R., Gupta, S., Wood, G., Shum, O., Miyakis, S., Dodek, P., Kwok, C. & Fowler, R. A. (2024). Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections. The New England journal of medicine.
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