Lab Information
Sapha Barkati (MD/MSc)
InvestigatorClinical Research Unit
Department of Medicine (McGill)
Research Profile
http://www.mcgill.ca/tropmed/
Keywords
Tropical medicine • travel medicine • migrant health • parasitology • neglected tropical diseases • epidemiologyResearch Interests
My research focuses on measuring the burden and improving the care of parasitic diseases such as strongyloidiasis and tegumentary leishmaniasis in vulnerable populations, with a focus on migrants and immunocompromised individuals. I am currently conducting studies on Strongyloides knowledge and awareness among Canadian physicians to build educational tools that will improve Strongyloides screening in the high-risk population. I am also studying the prevalence of Strongyloides in the immunocompromised population in non-endemic countries and the best screening strategy in that population. In collaboration with Universidad Peruana Cayetano Heredia in Lima, Peru, I am studying the response to Strongyloides stercoralis treatment in the HTLV-1 population. I am also interested in the management of tegumentary leishmaniasis in travellers and migrants. One of the ultimate goals of my research is to increase knowledge and awareness of neglected tropical diseases such as strongyloidiasis and tegumentary leishmaniasis among physicians in non-endemic countries. Another is to determine the most cost-effective strategies for Strongyloides screening in the high-risk population and the best treatment in the immunocompromised population and HTLV-1 co-infected, to inform evidence-based preventive clinical care and management guidelines.Team Members
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Latest Publications
- Ma, Y., Lessard, D., Vicente, S., Engler, K., Rodriguez Cruz, A., Laymouna, M., Opal-COVID Patient Expert Committee, Hijal, T., Del Balso, L., Thériault, G., Paisible, N., Kronfli, N., Pomey, M.-P., Peiris, H., Barkati, S., Brouillette, M.-J., Klein, M., Cox, J., de Pokomandy, A., Asselah, J., Bartlett, S. J. & Lebouché, B. (2024). Implementing a Patient Portal for the Remote Follow-Up of Self-Isolating Patients With COVID-19 Infection Through Patient and Stakeholder Engagement (the Opal-COVID Study): Mixed Methods Pilot Study. Journal of participatory medicine, vol. 16, p. e48194.
- Weckman, A. M., Guagliardo, S. A. J., Crowley, V. M., Moro, L., Piubelli, C., Ursini, T., van Ierssel, S. H., Gobbi, F. G., Emetulu, H., Rizwan, A., Angelo, K. M., Licitra, C., Connor, B. A., Barkati, S., Ngai, M., Zhong, K., Huits, R., Hamer, D. H., Libman, M. & Kain, K. C. (2024). Host Response Markers of Inflammation and Endothelial Activation Associated with COVID-19 Severity and Mortality: A GeoSentinel Prospective Observational Cohort. Viruses, vol. 16.
- Schweitzer, L., Barkati, S., Laneuville, P., Fox, S. & Vinh, D. C. (2024). Treatment of Progressive Multifocal Leukoencephalopathy with IL-2 and Mirtazapine. Journal of clinical immunology, vol. 44, p. 97.
- Bierbrier, R., Javelle, E., Norman, F. F., Chen, L. H., Bottieau, E., Schwartz, E., Leder, K., Angelo, K. M., Stoney, R. J., Libman, M., Hamer, D. H., Huits, R., Connor, B. A., Simon, F., Barkati, S. & GeoSentinel Network (2024). Chikungunya infection in returned travellers: results from the geosentinel network, 2005-2020. Journal of travel medicine, vol. 31.
- Dagher, O., Passos-Castilho, A. M., Sareen, V., Labbé, A.-C., Barkati, S., Luong, M.-L., Rousseau, C., Benedetti, A., Azoulay, L. & Greenaway, C. (2024). Impact of Language Barriers on Outcomes and Experience of COVID-19 Patients Hospitalized in Quebec, Canada, During the First Wave of the Pandemic. Journal of immigrant and minority health, vol. 26, p. 3-14.
- Chivinski, J., Nathan, K., Naeem, F., Ekmekjian, T., Libman, M. D. & Barkati, S. (2023). Intravenous Liposomal Amphotericin B Efficacy and Safety for Cutaneous and Mucosal Leishmaniasis: A Systematic Review and Meta-analysis. Open forum infectious diseases, vol. 10, p. ofad348.
- Huits, R., Angelo, K. M., Amatya, B., Barkati, S., Barnett, E. D., Bottieau, E., Emetulu, H., Epelboin, L., Eperon, G., Medebb, L., Gobbi, F., Grobusch, M. P., Itani, O., Jordan, S., Kelly, P., Leder, K., Díaz-Menéndez, M., Okumura, N., Rizwan, A., Rothe, C., Saio, M., Waggoner, J., Yoshimura, Y., Libman, M., Hamer, D. H. & Schwartz, E. (2023). Clinical Characteristics and Outcomes Among Travelers With Severe Dengue : A GeoSentinel Analysis. Annals of internal medicine, vol. 176, p. 940-948.
- Barkati, S., Greenaway, C. & Libman, M. (2023). Strongyloidiasis-related lung involvement: too much of a bad thing. Current opinion in infectious diseases, vol. 36, p. 203-208.
- Díaz-Menéndez, M., Angelo, K. M., de Miguel Buckley, R., Bottieau, E., Huits, R., Grobusch, M. P., Gobbi, F. G., Asgeirsson, H., Duvignaud, A., Norman, F. F., Javelle, E., Epelboin, L., Rothe, C., Chappuis, F., Martinez, G. E., Popescu, C., Camprubí-Ferrer, D., Molina, I., Odolini, S., Barkati, S., Kuhn, S., Vaughan, S., McCarthy, A., Lago, M., Libman, M. D. & Hamer, D. H. (2023). Dengue outbreak amongst travellers returning from Cuba-GeoSentinel surveillance network, January-September 2022. Journal of travel medicine, vol. 30.
- Harrison, L. B., Bergeron, G., Cadieux, G., Charest, H., Fafard, J., Levade, I., Blais, A. C., Huchet, E., Trottier, B., Vlad, D., Szabo, J., Thomas, R., Poulin, S., Greenaway, C., Zaharatos, G. J., Oughton, M., Chakravarti, A., Pilarski, R., Bui-Nguyen, A., Benomar, K., Libman, M. D., Vinh, D. C., Duggan, A. T., Graham, M., Klein, M. B. & Barkati, S. (2023). Monkeypox in Montréal: Epidemiology, Phylogenomics, and Public Health Response to a Large North American Outbreak. Annals of internal medicine, vol. 176, p. 67-76.
See also
