Lab Information
Giada Sebastiani (MD)
Senior ScientistCentre for Outcomes Research and Evaluation
Department of Medicine (McGill)
Research Profile
Keywords
Fatty liver • serum liver biomarkers • elastography • HIV • hepatitis C • hepatitis BResearch Interests
My research focuses on screening for liver fibrosis and fatty liver of at-risk populations, including HIV+ patients, patients with diabetes and obesity, women with polycystic ovary syndrome, and patients with inflammatory bowel syndrome. To conduct these studies, I employ serum fibrosis biomarkers and a non-invasive machine, which is ultrasound-based, named Fibroscan. I am also site investigator of multiple global clinical trials for antifibrotic compounds in NASH.Team Members
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Latest Publications
- Romano, J., Burnside, J., Sebastiani, G., Ramji, A., Patel, K., Swain, M. & Saeed, S. (2024). Examining the prevalence of hepatic steatosis and advanced fibrosis using non-invasive measures across Canada: A national estimate using the Canadian Health Measures Survey (CHMS) from 2009-2019. Annals of hepatology, p. 101757.
- Kronfli, N., Mambro, A., Riback, L. R., Ortiz-Paredes, D., Dussault, C., Chalifoux, S., Del Balso, L., Petropoulos, A., Lim, M., Halavrezos, A., Sebastiani, G., Klein, M. B., Lebouche, B., Cox, J. & Akiyama, M. J. (2024). Perceived patient navigator services and characteristics to address barriers to linkage to hepatitis C care among people released from provincial prison in Quebec, Canada. The International journal on drug policy, vol. 133, p. 104624.
- Truscello, E., Wang, S., Young, J., Sebastiani, G., Walmsley, S. L., Hull, M., Cooper, C. & Klein, M. B. (2024). Changes in hepatic steatosis before and after direct acting antiviral treatment in people living with HIV and Hepatitis C coinfection. The Journal of infectious diseases.
- Zeng, X.-F., Varady, K. A., Wang, X.-D., Targher, G., Byrne, C. D., Tayyem, R., Latella, G., Bergheim, I., Valenzuela, R., George, J., Newberry, C., Zheng, J.-S., George, E. S., Spearman, C. W., Kontogianni, M. D., Ristic-Medic, D., Peres, W. A. F., Depboylu, G. Y., Yang, W., Chen, X., Rosqvist, F., Mantzoros, C. S., Valenti, L., Yki-Järvinen, H., Mosca, A., Sookoian, S., Misra, A., Yilmaz, Y., Kim, W., Fouad, Y., Sebastiani, G., Wong, V.-W., Åberg, F., Wong, Y. J., Zhang, P., Bermúdez-Silva, F.-J., Ni, Y., Lupsor-Platon, M., Chan, W. K., Méndez-Sánchez, N., de Knegt, R. J., Alam, S., Treeprasertsuk, S., Wang, L., Du, M., Zhang, T., Yu, M.-L., Zhang, H., Qi, X., Liu, X., Pinyopornpanish, K., Fan, Y.-C., Kaijun, N., Jimenez-Chillaron, J. C. & Zheng, M.-H. (2024). The role of dietary modification in the prevention and management of metabolic dysfunction-associated fatty liver disease: an international multidisciplinary expert consensus. Metabolism: clinical and experimental, p. 156028.
- Volniansky, A., Lefebvre, T. L., Kulbay, M., Fan, B., Aslan, E., Vu, K.-N., Montagnon, E., Nguyen, B. N., Sebastiani, G., Giard, J.-M., Sylvestre, M.-P., Gilbert, G., Cloutier, G. & Tang, A. (2024). Inter-visit and inter-reader reproducibility of multi-parametric diffusion-weighted MR imaging in longitudinally imaged patients with metabolic dysfunction-associated fatty liver disease and healthy volunteers. Magnetic resonance imaging, vol. 113, p. 110223.
- Sachar, Y., Congly, S. E., Burak, K. W., Manko, A., Ko, H. H., Ramji, A., Rahman, H. S., Talia, J., Jeyaparan, J., Wong, D. W., Fung, S., Cooper, C., Kelly, E. M., Ma, M. M., Bailey, R., Minuk, G., Wong, A., Doucette, K., Elkashab, M., Sebastiani, G., Wong, P., Coffin, C. S. & Brahmania, M. (2024). Epidemiology, Treatment Patterns and Survival in Canadian Patients With Chronic Hepatitis B-Related Hepatocellular Carcinoma. Journal of viral hepatitis, vol. 31, p. 739-745.
- Yazdani, L., Selladurai, S., Rafati, I., Bhatt, M., Montagnon, E., Chayer, B., Olivié, D., Giard, J.-M., Sebastiani, G., Nguyen, B. N., Cloutier, G. & Tang, A. (2024). Between-Visit Reproducibility of Shear Wave Viscoelastography in Volunteers and Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, vol. 43, p. 2095-2108.
- Au, K., Zheng, M.-H., Lee, W.-J., Ghanem, O. M., Mahawar, K., Shabbir, A., le Roux, C. W., Targher, G., Byrne, C. D., Yilmaz, Y., Valenti, L., Sebastiani, G., Treeprasertsuk, S., Hui, H. X., Sakran, N., Neto, M. G., Kermansaravi, M., Kow, L., Seki, Y., Tham, K. W., Dang, J., Cohen, R. V., Stier, C., AlSabah, S., Oviedo, R. J., Chiappetta, S., Parmar, C., Yang, W. & Global Obesity Collaborative (2024). Resmetirom and Metabolic Dysfunction-Associated Steatohepatitis: Perspectives on Multidisciplinary Management from Global Healthcare Professionals. Current obesity reports, vol. 13, p. 818-830.
- Kablawi, D., Milic, J., Thomas, T., Fotsing Tadjo, T., Cinque, F., Elgretli, W., Gioè, C., Lebouché, B., Tsochatzis, E., Finkel, J., Bhagani, S., Cascio, A., Guaraldi, G., Mazzola, G., Saeed, S. & Sebastiani, G. (2024). Metabolic dysfunction-associated steatohepatitis exhibits sex differences in people with HIV. HIV medicine, vol. 25, p. 1259-1269.
- Riccardo, R., Cinque, F., Volpe, M. T. & Sebastiani, G. (2024). Integrating behavioral interventions into a Holistic Approach to Metabolic Dysfunction-Associated Steatotic liver disease. Expert review of gastroenterology & hepatology, p. 1-11.
See also
