Lab Information
Giada Sebastiani (MD)
Senior ScientistCentre for Outcomes Research and Evaluation
Department of Medicine (McGill)
Research Profile
Keywords
Fatty liver • serum liver biomarkers • elastography • HIV • hepatitis C • hepatitis BResearch Interests
My research focuses on screening for liver fibrosis and fatty liver of at-risk populations, including HIV+ patients, patients with diabetes and obesity, women with polycystic ovary syndrome, and patients with inflammatory bowel syndrome. To conduct these studies, I employ serum fibrosis biomarkers and a non-invasive machine, which is ultrasound-based, named Fibroscan. I am also site investigator of multiple global clinical trials for antifibrotic compounds in NASH.Team Members
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Latest Publications
- Zhou, X.-D., Huang, D. Q., Sebastiani, G. & Zheng, M.-H. (2026). The Changing Etiological Landscape of Liver Cancer in the Era of Metabolic Disease. Liver international : official journal of the International Association for the Study of the Liver, vol. 46, p. e70781.
- Pugliese, N., White, T. M., Brennan, P. N., Pannain, S., Hagström, H., Michel, M., Rice-Duek, L., Targher, G., Caussy, C., Dillon, J. F., Tacke, F., Kopka, C. J., Sebastiani, G., Boursier, J., Tsochatzis, E. A., Brouwer, W. P., Guaraldi, G., Vettor, R., Thiele, M., Roden, M., Stefan, N., Jarvis, H., Gines, P., Schattenberg, J. M., Pose, E., Buttigieg, S., Byrne, C. D. & Lazarus, J. V. (2026). Diagnostic innovation and models of care to improve fibrosis detection and risk stratification in steatotic liver disease. The Lancet regional health. Europe, vol. 65, p. 101722.
- White, T. M., Sebastiani, G., Guaraldi, G., Pericàs, J. M., Fuster-Ruizdeapodaca, M. J. & Lazarus, J. V. (2026). A people-first, systems-oriented approach to liver disease in HIV infection. Nature reviews. Gastroenterology & hepatology, vol. 23, p. 600-601.
- Cinque, F., Nudo, M., Saeed, S., Lim, J., Kablawi, D., Mariano, G., Lupu, A., Elgretli, W., Moodie, E. E. M., Price, C., Monteith, K., Cooper, C., Walmsley, S., Kronfli, N., Cox, J., Costiniuk, C., De Pokomandy, A., Routy, J.-P., Klein, M. B., Lebouche, B. & Sebastiani, G. (2026). Metabolic Dysfunction-Associated Steatotic Liver Disease Is Associated With Impaired Health-Related Quality of Life in People With HIV. Gastro hep advances, vol. 5, p. 100966.
- Lei, S.-Y., Han, Y., Rockey, D. C., Alswat, K., Wong, V.-W., Jumaev, N., Toro-Huamanchumo, C. J., Taha, S., El-Kassas, M., George, J., Muthiah, M., Ghanem, O., Yoneda, M., Hang, D. V., Sebastiani, G., Papatheodoridis, G., Abu-Abeid, A., Robertson, A. G., Kim, S. H., Weiner, R., Mahawar, K., Shabbir, A., Kermansaravi, M., Rajan, R., Seki, Y., Taskin, H. E., Shikora, S., Oliveros, E., Parmar, C., Cheng, Q., Thaher, O., Ruiz-Úcar, E., Oviedo, R., Ribeiro, R., Musella, M., Ramos, A. C., Ryu, S.-W., Abdelbaki, T., Lee, W. J., Chan, M. P., Garcia Flores, J. E., Skinovsky, J., Madkhali, A., Weiner, S., Tacke, F., Yang, W., Neuberger, J., Zheng, M.-H. & International Obesity Society Working Group on Steatotic Liver Disease (2026). An international multidisciplinary consensus statement on laparoscopic liver biopsy. Cell reports. Medicine, vol. 7, p. 102831.
- Farhat, R., Zamora-Medina, M. D. C., Bae, S.-C., Barber, M. R. W., Clarke, A. E., Fortin, P. R., Touma, Z., Laskin, C. A., Malhamé, I., Sebastiani, G., Peschken, C., Ugarte-Gil, M. F., Legge, A., Bernatsky, S. & Vinet, É. (2026). Increased Risk of Intrahepatic Cholestasis of Pregnancy in Women With Systemic Lupus Erythematosus Exposed to Azathioprine. Arthritis & rheumatology (Hoboken, N.J.).
- Cinque, F., Saeed, S., Farina, F., Kablawi, D., Lim, J., Cascio, A., Gioè, C., Tsochatzis, E., Lombardi, R., Cordie, A., Mohamed, R., Kamel, A. M., Esmat, G., Bandera, A., Milic, J., Benke, D., Elamouri, F., Rockstroh, J. K., Guaraldi, G. & Sebastiani, G. (2026). FIB-4 fails to identify significant liver fibrosis in people with HIV: A large multinational screening study. Hepatology (Baltimore, Md.).
- Burnside, J., Djerboua, M., Flemming, J. A., Sebastiani, G., Wong, W. W. L., Lu, Z., Bajaj, H. S., Patel, K., Biondi, M., Betel, M., Nahwegahbow, A., Greenwald, Z. R., Moodie, E. E. M. & Saeed, S. (2026). Reimbursement restrictions reduce liver fibrosis screening in adults with diabetes in Ontario: a population-based interrupted time series analysis. Scientific reports, vol. 16.
- Yoon, S. Y., El Bouzaidi Tiali, S., Wing, S., Davalan, W., Jatana, S., Slapcoff, L., Nitulescu, R., Rahme, E., Nakhla, M., Morin, S. N., Sebastiani, G. & Sapir-Pichhadze, R. (2026). Metabolic Dysfunction-Associated Steatotic Liver Disease and Kidney Transplant Outcomes. Kidney international reports, vol. 11, p. 106477.
- Zhou, X.-D., Sebastiani, G. & Zheng, M.-H. (2026). Reply to: "Hypertension and long-term adverse clinical outcomes in MASLD: Sensitivity analyses for unmeasured or uncontrolled confounding". Journal of hepatology, vol. 85, p. e24-e25.
See also
