Lab Information
Ana Copaescu (MD/PhD)
InvestigatorClinical Research Unit
Department of Medicine (McGill)
Research Profile
Keywords
Immune-mediated adverse drug reactions • severe cutaneous adverse reaction • point-of-care solutions • risk stratification tools • in vivo diagnostic tools • ex vivo diagnostic tools • clinical trialsResearch Interests
My research focuses on drug allergy−related pathologies, including their clinical identification, diagnostic methods and management. The ongoing clinical and translational research projects aim to improve precision diagnosis, including mechanisms to remove drug allergy labels and develop diagnostic tools. Additionally, I aim to advance our understanding of the complex, severe, delayed drug reactions associated with significant acute and long-term morbidity and mortality. These developments allow me to be part of a network of international collaborators, an excellent platform for exchanging and developing new projects. Addressing the significant health issue of immune-mediated drug allergy will lead to high-level research output that will translate into improvement in healthcare, locally and internationally.Team Members
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Latest Publications
- Copaescu, A. M., Belmont, A. P., Fadugba, O. O., Kraft, M. T. & Wolfson, A. R. (2026). Lessons Learned: Approaches to Delabeling Penicillin Allergy Population-level care - effective vs. ineffective strategies for delabeling penicillin allergy. The journal of allergy and clinical immunology. In practice.
- Mitri, E. A., Vogrin, S., Paynter, C., Fletcher, L. R., Peter, J., Powell, N., Barnes, S., Li, P. H., Copaescu, A. M., Turner, N. A., James, F., Sullivan, R., Masoum, M. S., Rawlins, M., Mackay, G., Smith, B. J., Kilfoyle, P., Forster, D., Rose, M., Cowan, R., Alcorn, K., Brischetto, A., Mahony, A., Redmond, A., Chakravorty, A., Meher-Homji, Z., Yuson, C., Crawford, S., Weeks, G., Ponnampalavanar, S. S. S., Katelaris, C., Tran, P., O'Hern, J., Godsell, J., Peel, T. N., Sandaradura, I., New, D., Holland, C., Cutfield, T., Coghill, S., Hand, C., Williams, J., Bishop, J., Lambros, B., Day, C., Ierano, C., Holmes, N. E., Roberts, J. A., Fernando, S. L., Klaic, M., Trubiano, J. A. & International Network of Antibiotic Allergy Nations (iNAAN) study group (2026). Direct Oral Challenge for Penicillin Allergy: A Hospital Implementation Evaluation Via the International Network of Antibiotic Allergy Nations (iNAAN) Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
- Mitri, E. A., Fletcher, L. R., Vogrin, S., Barnes, S., Powell, N., Peter, J., Li, P. H., Copaescu, A. M., Turner, N. A., James, F., Paynter, C., Sullivan, R., Masoum, M. S., Rawlins, M., Mackay, G., Smith, B. J., Kilfoyle, P., Forster, D., Rose, M., Cowan, R., Alcorn, K., Brischetto, A., Mahony, A., Redmond, A., Chakravorty, A., Meher-Homji, Z., Yuson, C., Crawford, S., Weeks, G., Ponnampalavanar, S. S. S., Katelaris, C., Tran, P., O'Hern, J., Godsell, J., Peel, T. N., Sandaradura, I., New, D., Holland, C., Cutfield, T., Coghill, S., Hand, C., Williams, J., Bishop, J., Lambros, B., Day, C., Ierano, C., Roberts, J. A., Holmes, N. E., Klaic, M., Fernando, S. L., Trubiano, J. A. & International Network of Antibiotic Allergy Nations (iNAAN) Study Group (2026). Direct Oral Challenge for Penicillin Allergy: The International Network of Antibiotic Allergy Nations (iNAAN) Study. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
- Mitri, E. A., Vogrin, S., Reynolds, G. K., Copaescu, A. M., Cox, F., Waldron, J. L., Peter, J. G., Trubiano, J. A. & International Network of Antibiotic Allergy Nations (iNAAN) study group (2026). Complex Problem, Digital Cure? Rethinking Penicillin Allergy Relabeling Using Technology-Enabled Care. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 82, p. e1135-e1137.
- Rose, M., Vogrin, S., Mitri, E. A., De Luca, J., Lapirow, D., Reynolds, G. K., Hall, R., McInnes, K., James, F., Ng, I., Sullivan, R., Lane, M., Legg, A., Copaescu, A., Goh, M. S., Chua, K. Y. L., Holmes, N. E. & Trubiano, J. A. (2026). Feasibility Trial of Prolonged versus Single-Dose Challenge in Penicillin Allergy. NEJM evidence, vol. 5, p. EVIDoa2500038.
- Copaescu, A. M., Ardern-Jones, M., Hickerson, N. K., Seccombe, E., Divito, S. J. & Peter, J. (2026). Blistering Drug Eruptions: Diagnostic Challenges and Management in Clinical Practice: Unmasking the Cause: A Grand Rounds Review of Blistering Drug Eruption. The journal of allergy and clinical immunology. In practice, vol. 14, p. 1074-1080.
- Byrne, A., Macdonald, D. B., Kirkpatrick, I. D. C., Pham, M., Copaescu, A. M., McInnes, M. D. F., Ling, L., Ellis, A. & Costa, A. F. (2025). CAR/CSACI Practice Guidance for Contrast Media Hypersensitivity: Update for Unknown Contrast Agents. Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes, p. 8465371251401551.
- Haddad, A., Mir, A. & Copaescu, A. M. (2025). [Not Available]. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, vol. 197, p. E1466-E1467.
- Belmont, A. P., Li, L., Tsao, L. R., Valente, M. S., Wolfson, A. R. & Copaescu, A. M. (2025). One Allergy, Two Paths: Navigating Penicillin Evaluation in Pregnant Patients Direct Challenges vs Penicillin Skin Testing in Pregnancy: A Controversies in Allergy Review. The journal of allergy and clinical immunology. In practice.
- Mitri, E. A., Reynolds, G. K., Copaescu, A. M., Cox, F., Waldron, J. L., Peter, J. G. & Trubiano, J. A. (2025). Executive Summary: State-of-the-Art Review: Antibiotic Allergy-A Multidisciplinary Approach to Delabeling. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol. 81, p. 693-694.
See also
