Lab Information
Marina Klein (MD/MSc)
Senior ScientistCentre for Outcomes Research and Evaluation
Department of Medicine (McGill)
Research Profile
http://www.cocostudy.ca/
Keywords
HIV • Hepatitis C • clinical trials • epidemiology • antiretrovirals • prospective cohortResearch Interests
My research program builds on years of multidisciplinary work leading one of the largest cohorts focused on HIV and hepatitis C virus (HCV) co-infection in the world. As Canada Research Chair in Clinical and Epidemiologic Studies of Chronic Viral Infections in Vulnerable Populations, I am documenting the impact of new HCV therapies on health outcomes, designing and testing tailored approaches to increase access to diagnosis and treatment, building capacity for research with Indigenous communities, and using evidence generated to advocate for policy change. My goal is to pave the way to eliminating HCV and other chronic viral infections in Canada and globally. To this end, I am leading an ambitious project called Montreal Sans Hep C, which aims to make Montreal the first City in North America to eliminate HCV.Team Members
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Latest Publications
- Zhabokritsky, A., Klein, M., Harris, M., Loutfy, M., Guillemi, S., Tan, D. H. S., Falutz, J., Andany, N., Guaraldi, G., Lovblom, L. E. & Walmsley, S. (2024). Prevalence and Correlates of Frailty Among Older Adults Living With HIV in the CHANGE HIV Cohort. Journal of acquired immune deficiency syndromes (1999), vol. 97, p. 226-231.
- Kronfli, N., Mambro, A., Riback, L. R., Ortiz-Paredes, D., Dussault, C., Chalifoux, S., Del Balso, L., Petropoulos, A., Lim, M., Halavrezos, A., Sebastiani, G., Klein, M. B., Lebouche, B., Cox, J. & Akiyama, M. J. (2024). Perceived patient navigator services and characteristics to address barriers to linkage to hepatitis C care among people released from provincial prison in Quebec, Canada. The International journal on drug policy, vol. 133, p. 104624.
- Truscello, E., Wang, S., Young, J., Sebastiani, G., Walmsley, S. L., Hull, M., Cooper, C. & Klein, M. B. (2024). Changes in hepatic steatosis before and after direct acting antiviral treatment in people living with HIV and Hepatitis C coinfection. The Journal of infectious diseases.
- Mboumba Bouassa, R.-S., Needham, J., Nohynek, D., Samarani, S., Bobeuf, F., Del Balso, L., Paisible, N., Vertzagias, C., Sebastiani, G., Margolese, S., Mandarino, E., Singer, J., Klein, M., Lebouché, B., Cox, J., Vulesevic, B., Müller, A., Lau, E., Routy, J.-P., Jenabian, M.-A. & Costiniuk, C. T. (2024). Feasibility of a Randomized, Interventional Pilot Clinical Study of Oral Cannabinoids in People with HIV on Antiretroviral Therapy: CTNPT 028. Journal of personalized medicine, vol. 14.
- Long, C., Cinque, F., Kablawi, D., Kim, D. H. D., Tadjo, T. F., Elgretli, W., Ballesteros, L. R., Lupu, A., Nudo, M., Lebouché, B., Kronfli, N., Cox, J., Costiniuk, C. T., De Pokomandy, A., Routy, J.-P., Klein, M. B., Lamonde, F., Agnihotram, R. V., Saeed, S. & Sebastiani, G. (2024). Material deprivation is associated with liver stiffness and liver-related outcomes in people with HIV. Liver international : official journal of the International Association for the Study of the Liver, vol. 44, p. 2615-2624.
- Bianco, O. E., Abdi, A., Klein, M. S., Wei, X., Sim, C. & Meuti, M. E. (2024). Consuming royal jelly alters several phenotypes associated with overwintering dormancy in mosquitoes. Frontiers in insect science, vol. 4, p. 1358619.
- Arora, A. K., Vicente, S., Engler, K., Lessard, D., Huerta, E., Ishak, J., Kronfli, N., Routy, J.-P., Cox, J., Lemire, B., Klein, M., de Pokomandy, A., Del Balso, L., Sebastiani, G., Vedel, I., Quesnel-Vallée, A., Lebouché, B. & ASAP Migrant Advisory Committee (2024). Patient-reported outcomes and experiences of migrants enrolled in a multidisciplinary HIV clinic with rapid, free, and onsite treatment dispensation: the 'ASAP' study. AIDS research and therapy, vol. 21, p. 40.
- Saeed, S., Thomas, T., Dinh, D. A., Moodie, E., Cox, J., Cooper, C., Gill, J., Martel-Laferriere, V., Panagiotoglou, D., Walmsley, S., Wong, A. & Klein, M. B. (2024). Frequent Disengagement and Subsequent Mortality Among People With HIV and Hepatitis C in Canada: A Prospective Cohort Study. Open forum infectious diseases, vol. 11, p. ofae239.
- Zhabokritsky, A., Klein, M., Loutfy, M., Guaraldi, G., Andany, N., Guillemi, S., Falutz, J., Arbess, G., Tan, D. H. S. & Walmsley, S. (2024). Non-AIDS-defining comorbidities impact health related quality of life among older adults living with HIV. Frontiers in medicine, vol. 11, p. 1380731.
- Passos-Castilho, A. M., Murphy, D. G., Blouin, K., Benedetti, A., Panagiotoglou, D., Bruneau, J., Klein, M. B., Kwong, J. C., Sander, B., Janjua, N. Z. & Greenaway, C. (2024). Ongoing Gaps in the Hepatitis C Care Cascade during the Direct-Acting Antiviral Era in a Large Retrospective Cohort in Canada: A Population-Based Study. Viruses, vol. 16.
See also
