Lab Information
Talat Bessissow (MD/MSc)
InvestigatorClinical Research Unit
Department of Medicine (McGill)
Research Profile
Keywords
Crohn's disease • ulcerative colitis • mucosal healing • neoplasia • pathogenesisResearch Interests
My research focuses on the role of mucosal healing in the treatment of inflammatory bowel diseases. I am also looking at identifying factor that predict disease relapse.Team Members
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Latest Publications
- Singh, S., Nguyen, J. D., Fudman, D. I., Gerich, M. E., Shah, S. A., Hudesman, D., McConnell, R. A., Lukin, D. J., Flynn, A. D., Hwang, C., Sprung, B., Gaidos, J. K. J., Mattar, M. C., Rubin, D. T., Hashash, J. G., Metwally, M., Ali, T., Ma, C., Hoentjen, F., Narula, N., Bessissow, T., Rosenfeld, G., McCurdy, J. D., Ananthakrishnan, A. N., Cross, R. K., Rodriguez Gaytan, J. R., Gurrola, E.-S., Patel, S., Siegel, C. A., Melmed, G. Y., Weaver, S. A., Power, S., Zou, G., Jairath, V. & Hou, J. K. (2025). Treat-to-target of endoscopic remission in patients with inflammatory bowel disease in symptomatic remission on advanced therapies (QUOTIENT): rationale, design and protocol for an open-label, multicentre, pragmatic, randomised controlled trial. BMJ open gastroenterology, vol. 12.
- McCurdy, J., Munir, J., Parlow, S., Sambhi, G., Reid, J., Yanofsky, R., Alenezi, T., Meserve, J., Yeh, K.-H., Becker, B., Lahijanian, Z., Eddin, A. H., Mallick, R., Ramsay, T., Rosenfeld, G., Bessissow, A., Bessissow, T., Jairath, V., Bruining, D. H., Macdonald, B., Singh, S. & Canadian IBD Research Consortium (CIRC) (2025). The Impact of Setons on Perianal Fistula Outcomes in Patients With Crohn's Disease Treated With Anti-TNF Therapy: A Multicentre Study. Alimentary pharmacology & therapeutics.
- Narula, N., Pray, C., Hamam, H., Peerani, F., Hansen, T., Bessissow, T., Bressler, B., Arun, A., Schmit, M., Castelli, J. & Marshall, J. K. (2025). Tofacitinib for Hospitalized Acute Severe Ulcerative Colitis Management (The TRIUMPH Study). Crohn's & colitis 360, vol. 7, p. otaf013.
- Shehab, M., Al-Hindawi, A. & Bessissow, T. (2025). Editorial: Surveillance Colonoscopy for Detection of Neoplasia in Inflammatory Bowel Disease-Is Dye-Based Chromoendoscopy Always the Final Answer? Authors' Reply. Alimentary pharmacology & therapeutics, vol. 61, p. 1252-1253.
- Qatomah, A., Bessissow, A., Chen, Y.-I., Bessissow, T. & Benmassaoud, A. (2025). Management of Refractory Esophageal Variceal Bleeding when TIPSS Is Not Possible: Review of a Challenging Case. Case reports in gastroenterology, vol. 19, p. 67-71.
- Ngew, E., Kollipara, R., Bessissow, T., Karboune, S. & George, S. (2025). Nanoencapsulation enhanced the performance of β-carotene for ameliorating inflammation in patient-derived organoids. Nanomedicine (London, England), p. 1-13.
- Candel, I., Wetwittayakhlang, P., Bessissow, T. & Lakatos, P. L. (2025). The Importance of Post-Inflammatory Polyps (PIPs) in Colorectal Cancer Surveillance in Inflammatory Bowel Diseases. Journal of clinical medicine, vol. 14.
- Shehab, M., Al-Hindawi, A., Alrashed, F., Murthy, S., Bisschops, R., Hoentjen, F., Barkun, A., Singh, S. & Bessissow, T. (2025). Network Meta-Analysis: Comparison of Endoscopic Dysplasia Detection Technologies in Inflammatory Bowel Disease. Alimentary pharmacology & therapeutics, vol. 61, p. 938-949.
- Farkas, B., Bessissow, T., Limdi, J. K., Sethi-Arora, K., Kagramanova, A., Knyazev, O., Bezzio, C., Armuzzi, A., Lukas, M., Michalopoulos, G., Chaskova, E., Savarino, E. V., Castiglione, F., Rispo, A., Schäfer, E., Saibeni, S., Filip, R., Attauabi, M., Fousekis, F. S., Bacsur, P., Resál, T., Bálint, A., Ivány, E., Szepes, Z., Bősze, Z., Fábián, A., Bor, R., Farkas, K., Lakatos, P. L. & Molnár, T. (2024). Real-World Effectiveness and Safety of Selective JAK Inhibitors in Ulcerative Colitis and Crohn's Disease: A Retrospective, Multicentre Study. Journal of clinical medicine, vol. 13.
- Solitano, V., Narula, N., Ma, C., Nanayakkara, A., Suarez, K. E., Zoughlami, A., Guizzetti, L., Bessissow, T. & Jairath, V. (2024). Effectiveness of Ustekinumab for patients with moderate to severe Ulcerative Colitis: A Multi-Center Real-World Canadian Study. The American journal of gastroenterology.
See also
