Lab Information
Talat Bessissow (MD/PhD)
Associate InvestigatorClinical Research Unit
Department of Medicine (McGill)
Keywords
Crohn's disease • ulcerative colitis • mucosal healing • neoplasia • pathogenesisResearch Interests
My research focuses on the role of mucosal healing in the treatment of inflammatory bowel diseases. I am also looking at identifying factor that predict disease relapse.Team Members
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Latest Publications
- Alenezi, T., Marcus, V. & Bessissow, T. (2023). A Case Report and Literature Review of a Rare Jejunal Solitary Peutz-Jeghers-Type Polyp Resected Endoscopically in an Elderly Patient Presenting with Subacute Gastrointestinal Bleeding. Case reports in gastrointestinal medicine, vol. 2023, p. 2391602.
- Vuyyuru, S. K., Ma, C., Sharma, T., Nguyen, T. M., Bessissow, T., Narula, N., Singh, S., Rieder, F. & Jairath, V. (2023). Characteristics of Interventional Trials for Patients Living With Intestinal Stoma Registered in ClinicalTrials.gov With a Focus on Inflammatory Bowel Disease. Inflammatory bowel diseases.
- McCurdy, J., Munir, J., Parlow, S., Reid, J., Yanofsky, R., Alenezi, T., Meserve, J., Becker, B., Lahijanian, Z., Eddin, A. H., Mallick, R., Ramsay, T., Rosenfeld, G., Bessissow, A., Bessissow, T., Jairath, V., Singh, S., Bruining, D. H., Macdonald, B. & Canadian IBD Research Consortium (CIRC) (2023). Development of an MRI-based prediction model for anti-TNF treatment failure in perianal Crohn's disease: A multicenter study. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
- Bessissow, T., Narula, N., Ma, C., In, T. S. H., Eberg, M., Karra, K., Jairath, V. & Canadian IBD Research Consortium (2024). Real-world effectiveness and safety of ustekinumab in bio-naive patients with moderate-to-severe Crohn's disease: A Canadian multi-center study. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, vol. 56, p. 61-69.
- Shehab, M., Al Akram, S., Hassan, A., Alrashed, F., Jairath, V. & Bessissow, T. (2024). Histological Disease Activity as Predictor of Clinical Relapse, Hospitalization, and Surgery in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis. Inflammatory bowel diseases, vol. 30, p. 563-572.
- Wetwittayakhlang, P., Karkout, K., Wongcha-Um, A., Tselekouni, P., Al-Jabri, R., Afif, W., Wild, G., Bitton, A., Bessissow, T. & Lakatos, P. L. (2024). Clinical efficacy and nocebo effect following non-medical biosimilar switch in patients with inflammatory bowel disease: A prospective observational study. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, vol. 56, p. 35-42.
- Khanna, R., Ma, C., Hogan, M., Zou, G., Bessissow, T., Bressler, B., Colombel, J.-F., Danese, S., Daperno, M., East, J. E., Hookey, L., Loftus, E. V., McDonald, J. W. D., Panaccione, R., Peyrin-Biroulet, L., Rutter, M., Sands, B. E., Vermeire, S., Rémillard, J., McFarlane, S. C., Sandborn, W. J., D'Haens, G. R., Feagan, B. G. & Jairath, V. (2023). Standardizing Scoring Conventions for Crohn's Disease Endoscopy: An International RAND/UCLA Appropriateness Study. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 21, p. 2938-2950.e6.
- Alphonsus, L., De Silva, T. A., Ma, C., MacDonald, J. K., Hanzel, J., Beaton, M., Bessissow, T., Kayal, M., Sedano, R., Singh, S. & Jairath, V. (2023). Systematic review and meta-analysis of randomised controlled trials: Medical therapies for the treatment and prevention of pouchitis. Alimentary pharmacology & therapeutics, vol. 58, p. 268-282.
- Rivière, P., Le Chevillier, A., Rullier, A., Marty, M., Schurr, E., Lapuyade, B., Célerier, B., Fernandez, B., Bessissow, T., Treton, X., Uzzan, M., Poullenot, F., Berger, A., Zerbib, F. & Laharie, D. (2023). Deep ulcers are associated with increased C-reactive protein in active ulcerative colitis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, vol. 55, p. 1194-1200.
- Wetwittayakhlang, P., Verdon, C., Starr, M., Hahn, G. D., Golovics, P. A., Bessissow, T., Afif, W., Wild, G., Bitton, A. & Lakatos, P. L. (2023). Mucosal Healing and Clinical Efficacy of Adalimumab in Small Intestinal Crohn's Disease (SIMCHA Study): Final Results From a Prospective, Open-Label, Single-Arm Study. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, vol. 34, p. 603-610.