Lab Information
Moshe Ben-Shoshan (MD/MSc)
ScientistCentre for Outcomes Research and Evaluation
Department of Pediatrics (McGill)
Research Profile
Keywords
Food allergy • anaphylaxis • immunodeficiency • chronic urticariaResearch Interests
My research focuses on the prevalence and potential determinants of food allergies and anaphylaxis (severe allergic reactions) in children. In addition, I have established a registry aiming to assess triggers and management of different forms of chronic urticaria, or hives. I also conduct research on primary immunodeficiencies, exploring the ability of children's immune systems to fight infectious disease. In collaboration with Dr. Ann Clarke at the Montreal General Hospital of the MUHC, I conducted the first nationwide Canadian study to determine the prevalence of severe food allergies. The results indicate disparities between perceived and confirmed food allergy that might contribute to the wide range of published prevalence estimates. In recent years I have led the first Canada-wide anaphylaxis registry exploring the societal burden, triggers, management and natural history of anaphylaxis in Canadians.Team Members
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Latest Publications
- Arnau-Soler, A., Tremblay, B. L., Sun, Y., Madore, A.-M., Simard, M., Kersten, E. T. G., Ghauri, A., Marenholz, I., Eiwegger, T., Simons, E., Chan, E. S., Nadeau, K., Sampath, V., Mazer, B. D., Elliott, S., Hampson, C., Soller, L., Sandford, A., Begin, P., Hui, J., Wilken, B. F., Gerdts, J., Bourkas, A., Ellis, A. K., Vasileva, D., Clarke, A., Eslami, A., Ben-Shoshan, M., Martino, D., Daley, D., Koppelman, G. H., Laprise, C., Lee, Y.-A. & Asai, Y. (2024). Food Allergy Genetics and Epigenetics: A Review of Genome-Wide Association Studies. Allergy.
- Ben-Shoshan, M., Kanani, A., Kalicinsky, C. & Watson, W. (2024). Urticaria. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, vol. 20, p. 64.
- Stehlin, F., Prosty, C., Mulé, A., Al-Otaibi, I., Colli, L. D., Gaffar, J., Yu, J., Lanoue, D., Copaescu, A.-M. & Ben-Shoshan, M. (2024). Guiding drug provocation testing for ibuprofen hypersensitivity in a pediatric population: Development of the I3A risk-stratification tool. The journal of allergy and clinical immunology. In practice.
- Prosty, C., Le, M., Lu, Y., Khoury, L., Cormier, M., Cheng, M. P., Fowler, R., Murthy, S., Tsang, J. L., Lejtenyi, D., Ben-Shoshan, M., Rahme, E., Golchi, S., Dendukuri, N., Lee, T. C. & Netchiporouk, E. (2024). Effect of omalizumab on inflammatory markers in COVID-19: an exploratory analysis of the COVID-19 immunologic antiviral therapy with omalizumab (CIAO) trial. Frontiers in medicine, vol. 11, p. 1437322.
- Khalaf, R., Prosty, C., McCusker, C., Bretholz, A., Kaouache, M., Clarke, A. E., Morris, J., Lim, R., Chan, E. S., Goldman, R. D., O'Keefe, A., Gerdts, J., Chu, D. K., Upton, J., Hochstadter, E., Moisan, J., Zhang, X., Protudier, J. L. P., Abrams, E., Simons, E., Ruiz, J. & Ben-Shoshan, M. (2024). Symptomatology and Management of Adult Anaphylaxis according to Trigger: A Cross-Sectional Study. International archives of allergy and immunology, p. 1-11.
- Al Ali, A., Sigman, K., Khalaf, R., Sillcox, C., Kaouache, M., Shand, G., Saker, S., McCusker, C. & Ben-Shoshan, M. (2024). Comparing Two Peanut Desensitization Protocols in Preschool Children: A Real-World Clinical Practice. International archives of allergy and immunology, p. 1-10.
- Khalaf, R., Prosty, C., McCusker, C., Bretholz, A., Kaouache, M., Clarke, A. E. & Ben-Shoshan, M. (2024). Diagnostic Accuracy of Tryptase Levels for Pediatric Anaphylaxis: A Case-Control Study. International archives of allergy and immunology, p. 1-8.
- ALOtaibi, I., Khoudja, R. Y., Isabwe, G. A. C., Fein, M., Stehlin, F., James, F., Ben-Shoshan, M., Trubiano, J. A. & Copaescu, A. M. (2024). Tolerance of penicillin V in patients with confirmed delayed hypersensitivity reactions to aminopenicillins. The journal of allergy and clinical immunology. In practice.
- Buyansky, D., Khalaf, R., Gabrielli, S., Upton, J., Grunebaum, E., Chan, E. S., Baerg, I., Beaudette, L., Ke, D., Mazer, B., McCusker, C., Lejtenyi, D. & Ben-Shoshan, M. (2024). Anaphylaxis Management in Paediatric Patients Undergoing Milk Oral Immunotherapy. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
- Sillcox, C., Gabrielli, S., O'Keefe, A., McCusker, C., Abrams, E. M., Eiwegger, T., Atkinson, A., Kim, V., Copaescu, A.-M. & Ben-Shoshan, M. (2024). Evaluating Pediatric Macrolide Allergy Using Direct Graded Oral Challenges. JAMA pediatrics, vol. 178, p. 1362-1364.
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