Lab Information
Alain Bitton (MD)
InvestigatorClinical Research Unit
Department of Medicine (McGill)
Research Profile
Keywords
Crohn's disease • ulcerative colitis • psychosocial • biologic markers • geneticsTeam Members
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Latest Publications
- Di Fonzo, D. M. P., Alabdulkarim, B., Yanofsky, R., Abduallah, Y., Golovics, P., Lakatos, P. L., Bitton, A., Wild, G., Afif, W. & Bessissow, T. (2024). Association Between Serum Ustekinumab Concentrations and Endoscopic Disease Activity in Moderate-to-Severe Crohn's Disease Patients. Crohn's & colitis 360, vol. 6, p. otae071.
- Rioux, J. D., Boucher, G., Forest, A., Bouchard, B., Coderre, L., Daneault, C., Frayne, I. R., Legault, J. T., iGenoMed Consortium, Bitton, A., Ananthakrishnan, A., Lesage, S., Xavier, R. J. & Des Rosiers, C. (2024). A pilot study to identify blood-based markers associated with response to treatment with Vedolizumab in patients with Inflammatory Bowel Disease. medRxiv : the preprint server for health sciences.
- Ivison, S., Boucher, G., Zheng, G., Garcia, R. V., Kohen, R., Bitton, A., Rioux, J. D., Levings, M. K. & iGenoMed Consortium (2024). Improving Reliability of Immunological Assays by Defining Minimal Criteria for Cell Fitness. ImmunoHorizons, vol. 8, p. 622-634.
- Olivera, P. A., Martinez-Lozano, H., Leibovitzh, H., Xue, M., Neustaeter, A., Espin-Garcia, O., Xu, W., Madsen, K. L., Guttman, D. S., Bernstein, C. N., Yerushalmi, B., Hyams, J. S., Abreu, M. T., Marshall, J. K., Wrobel, I., Mack, D. R., Jacobson, K., Bitton, A., Aumais, G., Panacionne, R., Dieleman, L. A., Silverberg, M. S., Steinhart, A. H., Moayyedi, P., Turner, D., Griffiths, A. M., Turpin, W., Lee, S.-H., Croitoru, K. & Crohn’s and Colitis Canada (CCC) Genetic, Environmental, Microbial (GEM) Project Research Consortium (2025). Healthy first-degree relatives from multiplex families versus simplex families have a higher subclinical intestinal inflammation, a distinct fecal microbial signature, and harbor a higher risk of developing Crohn's disease. Gastroenterology, vol. 168, p. 99-110.e2.
- Rocha, C.-H., Turpin, W., Borowski, K., Stempak, J. M., Sabic, K., Gettler, K., Tastad, C., Chasteau, C., Korie, U., Hanna, M., Khan, A., Mengesha, E., Bitton, A., Schwartz, M. B., Barrie, A., Datta, L. W., Lazarev, M., Brant, S. R., Rioux, J. D., McGovern, D. P. B., Duerr, R. H., Schumm, L. P., Cho, J. H. & Silverberg, M. S. (2024). After surgically induced remission, ileal and colonic mucosa-associated microbiota predicts Crohn's disease recurrence. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
- Xue, M., Leibovitzh, H., Jingcheng, S., Neustaeter, A., Dong, M., Xu, W., Espin-Garcia, O., Griffiths, A. M., Steinhart, A. H., Turner, D., Huynh, H. Q., Dieleman, L. A., Panaccione, R., Aumais, G., Bressler, B., Bitton, A., Murthy, S., Marshall, J. K., Hyams, J. S., Otley, A., Bernstein, C. N., Moayyedi, P., El-Matary, W., Fich, A., Denson, L. A., Ropeleski, M. J., Abreu, M. T., Deslandres, C., Cino, M., Avni-Biron, I., Lee, S.-H., Turpin, W., CCC GEM Project Research Consortium & Croitoru, K. (2024). Environmental Factors Associated with Risk of Crohn's Disease Development in the CCC-GEM Project. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, vol. 22, p. 1889-1897.e12.
- Bernstein, C. N., Panaccione, R., Nugent, Z., Marshall, D. A., Kaplan, G. G., Vanner, S., Dieleman, L. A., Graff, L. A., Otley, A., Jones, J., Buresi, M., Murthy, S., Borgaonkar, M., Bressler, B., Bitton, A., Croitoru, K., Sidani, S., Fernandes, A. & Moayyedi, P. (2024). Crohn's Disease Phenotypes and Associations With Comorbidities, Surgery Risk, Medications and Nonmedication Approaches: The MAGIC in IMAGINE Study. Inflammatory bowel diseases.
- Kuenzig, M. E., Stukel, T. A., Carroll, M. W., Kaplan, G. G., Otley, A. R., Singh, H., Bitton, A., Fung, S. G., Spruin, S., Coward, S., Cui, Y., Nugent, Z., Griffiths, A. M., Mack, D. R., Jacobson, K., Nguyen, G. C., Targownik, L. E., El-Matary, W., Bernstein, C. N., Dummer, T. J. B., Jones, J. L., Lix, L. M., Murthy, S. K., Peña-Sánchez, J. N., Nasiri, S., Benchimol, E. I. & Canadian Gastro-Intestinal Epidemiology Consortium (2024). Variation in the Care of Children with Inflammatory Bowel Disease Within and Across Canadian Provinces: A Multi-Province Population-Based Cohort Study. Clinical epidemiology, vol. 16, p. 91-108.
- Kuenzig, M. E., Bitton, A., Carroll, M. W., Otley, A. R., Singh, H., Kaplan, G. G., Stukel, T. A., Mack, D. R., Jacobson, K., Griffiths, A. M., El-Matary, W., Targownik, L. E., Nguyen, G. C., Jones, J. L., Murthy, S. K., Bernstein, C. N., Lix, L. M., Peña-Sánchez, J. N., Dummer, T. J. B., Spruin, S., Fung, S. G., Nugent, Z., Coward, S., Cui, Y., Coulombe, J., Filliter, C. & Benchimol, E. I. (2024). Health Services Utilization and Specialist Care in Pediatric Inflammatory Bowel Disease: A Multiprovince Population-Based Cohort Study. Inflammatory bowel diseases, vol. 30, p. 2356-2369.
- Coward, S., Benchimol, E. I., Bernstein, C. N., Avina-Zubieta, A., Bitton, A., Carroll, M. W., Cui, Y., Hoentjen, F., Hracs, L., Jacobson, K., Jones, J. L., King, J., Kuenzig, M. E., Lu, N., El-Matary, W., Murthy, S. K., Nugent, Z., Otley, A. R., Panaccione, R., Peña-Sánchez, J. N., Singh, H., Targownik, L. E., White, D., Windsor, J. W., Kaplan, G. G. & Canadian Gastro-Intestinal Epidemiology Consortium (CanGIEC) (2024). Forecasting the Incidence and Prevalence of Inflammatory Bowel Disease: A Canadian Nationwide Analysis. The American journal of gastroenterology, vol. 119, p. 1563-70.
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