Lab Information
Todd Lee (MD)
ScientistClinical Research Unit
Department of Medicine (McGill)
Research Profile
https://www.drtoddlee.com/
Keywords
Quality improvement • patient safety • high value healthcare • antibiotic stewardship • polypharmacyResearch Interests
My research focuses on conducting randomized clinical trials designed to improve the treatment of infectious diseases (e.g., C. difficile, COVID-19, S. aureus, Gram-Negative infections) and to innovate in the domains of care of complex hospitalized patients, care of older adults with polypharmacy, and stewardship of healthcare resources (e.g., testing, medications).Team Members
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Latest Publications
- Filosa, E., Schönenberger, N., Essien, U. R., Gagnon, C., Gnjidic, D., Kouladjian O'Donnell, L., Manias, E., McCarthy, L. M., Moriarty, F., Nguyen-Soenen, J., Scott, S., Steinman, M. A., Thürmann, P. A., Wilson, M. G., Gutman, B. J., Mendel, A., Trinh, E., Lee, T. C. & McDonald, E. G. (2026). Identification of Potentially Inappropriate Medications for Adults Below 65 Years: Protocol for a Modified Delphi Study. JMIR research protocols, vol. 15, p. e92082.
- Goodman, A. L., Easom, N., Bielopolski, D., Sutherland, R. K., Marks, M., Hensgens, M. P. M., Bonten, M., Bostock, J., Walls, G., Lye, D., Boyles, T., Yahav, D., Cheng, M. P., Legg, A., Paul, M., Lescure, F.-X., Lee, T. C., Tong, S. Y. C. & Davis, J. S. (2026). A review of the randomized clinical trial results from the Staphylococcus aureus network adaptive platform (SNAP) meticillin-susceptible (MSSA) and penicillin-susceptible (PSSA) domains and CloCeBa. The Journal of antimicrobial chemotherapy, vol. 81.
- Staphylococcus aureus Network Adaptive Platform (SNAP) Trial Group, Lee, T. C., Barina, L. A., Walls, G., Goodman, A. L., Yahav, D., Cheng, M. P., Bonten, M., Bowen, A. C., Boyles, T., Daneman, N., Ekkelenkamp, M. B., Ghanem-Zoubi, N., Hensgens, M. P. M., Jager, N. G. L., Kaasch, A. J., Kouijzer, I. J. E., Lewis, R. J., Lumley, T., Lye, D. C., McDonald, E. G., McKew, G., McLean, A. R. D., McMullan, B. J., McQuilten, Z. K., Morpeth, S. C., Paterson, D. L., Roberts, J. A., Robinson, J. O., Saito, H., Scarborough, M., Ten Oever, J., Turner, R. M., Tverring, J., van Hal, S. J., Webb, S. A., Whiteway, L. M., Arias, C. A., Henderson, A., Heriot, G. S., Snelling, T. L., Afra, K., Ali, S. S., Amit, S., Anagnostou, N. A., Archuleta, S., Aston, S. J., Athan, E., Baharav, N., Bai, A. D., Barber, B. E., Baskaran, A., Berkeley, M. M. A., Best, E. J., Bhilave, N. R., Bloomfield, M. G., Bond, K. A., Bostock, J., Botheras, C. L., Boyd, M. A., Bradshaw, S. M. E., Briggs, E. J., Britton, P. N., Campbell, A. J., Carr, B. Z., Chancellor, J. A., Chen, K., Cheong, E. Y., Chew, K. L., Chia, P. Y., Chomba, R., Chong, B. S. W., Clews, C. J. N., Cohen, J. M., Commons, R. J., Cutfield, T., Daley, P., Daniel, D. S., Davies, J., De, P., Denholm, J. T., Di Virgilio, M., Dishon-Benattar, Y., Dotel, R., Duan, E. H., Easom, N., Eliakim-Raz, N., England, M. M., Fahmy, M., Findlater, A. R., Flanagan, K. L., Foo, E. Z. J., Foo, H., Forster, D. P., Fralick, M., Frazer, J. L., Gador-Whyte, A. P., Garnham, K., German, G. J., Ghosh, N., Gisolf, E. H., Giulieri, S. G., Goulding, S. R., Grant, J. M., Gregson, D., Grimwade, K. C., Grupper, M., Guy, S. D., Gwee, A., Hall, V. G., Hardy, E. J., Harris, D. J., Hatcher, J., Hobbs, M. R., Holmes, N. E., Howden, B. P., Huggan, P. J., Jennings, Z. A., Johnstone, J., Juniper, T., Kalimuddin, S., Kamfose, M., Kandel, C., Kelly, M. J., Kozak, R. A., Kümin, M., Lamontagne, F., Lau, J. S. Y., Lee, I. R., Lin, R. J., Lindsay, D., Llewelyn, M. J., Longtin, Y., Lother, S. A., Luey, C. E., MacFadden, D. R., Mahony, A. A., Malden, C., Malhamé, I., Manning, L. A., Marks, M., Martin, L. J., Matthews, G. V., McGann, P. H., McMahon, J. H., Melon, A., Menon, V., Mertz, D., Meyer, M. P., Molton, J. S., Mora, J. M., Moran, E., Mortimer, L. M., Motaganahalli, S., Muller, M. P., Munro, A. P. S., Murray, F. A., Murthy, S., Nagendra, V., Nel, H., New, D. W. J., Nguyen, V., Norton, G., Norton, K. M., Nourse, C. B., Nye, C. J. S., O'Callaghan, K., O'Sullivan, M. V. N., Ong, S. W. X., Otu, A. A., Owen, M., Papenburg, J., Parkes, L. O., Paul, M., Perez-Patrigeon, S., Petersiel, N., Petrella, L., Pett, S. L., Pham, D., Piazzese, C. J., Poulin, S., Rehak, R., Rennert-May, E., Richards, A. J., Rogers, B. A., Sahng, E., Salada, B., Scheuerman, O., Schneider, K., Schulz, T. R., Schwartz, K. L., Simos, P. A., Singh, H., Sinkeler, F. S., Smith, S., Smith, B. J., Smith, S. W., Somayaji, R., Sommerville, C., Song, R. X. J., Sowden, D. C., Stark, M. J., Stone, N. R. H., Strunk, T., Sud, A., Swe, K. P., Symons, C. R., Tan, Y. E., Ten Doesschate, T., Thien, S. Y., Thomas, A., Trad, M.-A., Tramontana, A. R., Tsang, J. L. Y., Ulett, K., Underwood, J., van Welzen, B. J., Vazquez-Grande, G., Velasquez Reyes, D. C., Verberk, J. D. M., Voss, L. M., Ward, D., Webb, R. H., Whitmore, T. J., Wieder-Finesod, A., Wilson, H. L., Wilson, E. W., Wong, H. M., Wong She, K., Wuerz, T., Yamamura, D. L., Yeoh, A., Yow, B. L. H., Dymock, M., Mahar, R. K., McGlothlin, A., Marsh, J. A., Davis, J. S. & Tong, S. Y. C. (2026). Cefazolin for Methicillin-Susceptible Staphylococcus aureus Bacteremia. The New England journal of medicine, vol. 394, p. 2329-2339.
- Hamani, M., Pinto, R., Lee, T. C., MacFadden, D., McDonald, E. G., Sligl, W., Fowler, R. A., Daneman, N. & BALANCE consortium (2026). Duration of antibiotic therapy for bacteraemia in immune compromised hosts-a post-hoc subgroup analysis of the Bacteremia Antibiotic Length Actually Needed For Clinical Effectiveness (BALANCE) randomized clinical trial. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
- Lasry, D., Harrison, L. B., Bamba, R., Corsini, R., Yansouni, C. P., Cheng, M. P., Lee, T. C. & Lawandi, A. (2026). In vitro exposure to non-antipseudomonal antibiotics (NAPA) induces Pseudomonas aeruginosa resistance to antipseudomonal antibiotics (APA). The Journal of antimicrobial chemotherapy, vol. 81.
- Harrison, L. B., Sohani, Z. N., Lasry, D., Cheng, M. P., Lee, T. C., Babiker, A., Kadri, S. S. & Lawandi, A. (2026). Rapid Microbiological Diagnostics for Sepsis: Narrative Review of Current and Prospective Approaches. Critical care explorations, vol. 8, p. e1415.
- Cabanilla, M. G., Ghanem, B., Jegorović, B., Lee, T. C., Chahine, E. B., Anderson, D. T., Salgado, N. K., Eudy, J., Singh, H. K., Muyidi, A. A., Astorri, R., Maraolo, A. E., Antolí Royo, A. C., Mena Lora, A. J., Pimentel, B. V. & Spellberg, B. (2026). Universal high-dose meropenem for antimicrobial-resistant Gram-negative infections: evidence or overreach?. European journal of hospital pharmacy : science and practice.
- Prosty, C., Desormeau, B., Lee, T. C. & McDonald, E. G. (2026). Diagnosis, treatment, and prophylaxis of Clostridioides difficile infections: A cross-sectional survey of Canadian clinicians. Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada, vol. 11, p. 37-50.
- Hamilton, F., Lee, T. C., Davey Smith, G., Hartwig, F. P. & Butler-Laporte, G. (2026). The illusion of causality: Instruments, colliders, and acute kidney injury in sepsis. American journal of respiratory and critical care medicine.
- Ross, S. B., Bortolussi-Courval, É., Juhásová, Z., Weir, D. L., Wilson, A. G., Lee, T. C., McDonald, E. G. & Wilson, M. G. (2026). Measuring Medication Related Harm: Proposed Guidance for Adverse Drug Event Adjudication to Harmonize Outcomes in Deprescribing Research. Journal of the American Geriatrics Society.
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