Lab Information

Bernard Turcotte (PhD)

Centre for Translational Biology
Department of Medicine (McGill)

Research Profile

 Fundamental: 100%
 Clinical: 0%
 Epidemiology: 0%
 Evaluation: 0%
 This email address is being protected from spambots. You need JavaScript enabled to view it.


Pathogenic fungi • transcription factors • drug resistance • genome-wide analysis

Research Interests

My research focuses on functional genomics in budding yeast and the human fungal pathogen Candida glabrata. We are focusing on the Gal4 family of transcriptional regulators. The function of many of these Gal4 members is unknown or poorly defined. To better understand the role of these transcriptional regulators and identify their target genes, we are using various approaches including genetics, molecular biology and whole-genome analysis of gene expression with DNA microarrays. We are also determining the role of related Gal4 members in conferring resistance to antifungal drugs in the human pathogen Candida glabrata.

Team Members

Name Position

Latest Publications

  1. Turcotte, B. (2022). Editorial: Functional Genomics of Transcriptional Regulation in Pathogenic Fungi. Frontiers in cellular and infection microbiology, vol. 12, p. 928440.
  2. Klimova, N., Chu, S. & Turcotte, B. (2021). A lacZ reporter with high activity in the human fungal pathogen Candida albicans. FEMS yeast research, vol. 21.
  3. Zhang, E., Khanna, V., Dacheux, E., Namane, A., Doyen, A., Gomard, M., Turcotte, B., Jacquier, A. & Fromont-Racine, M. (2019). A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes. The EMBO journal, vol. 38, p. e100640.
More on PubMed