Lab Information
Madhukar Pai (MD/PhD)
Senior ScientistCentre for Outcomes Research and Evaluation
Department of Epidemiology, Biostatistics and Occupational Health (McGill)
Research Profile
https://www.paitbgroup.org/
Keywords
Tuberculosis • diagnostics • epidemiology • global health • implementation researchResearch Interests
My research focuses on tuberculosis. It is a major threat to human health, with 9 million new cases and 1.5 million deaths every year. I have focused my career on improving tuberculosis diagnosis and care, with research that includes evaluating diagnostics tests that could eventually be part of country-level policies, implementation of tools and policies, and improving tuberculosis care for vulnerable populations in different countries worldwide. For example, I have compared the accuracy and usefulness of new tests that can diagnose tuberculosis in a few hours to conventional techniques which may require days before results are known. I am also conducting a study using mystery patients to evaluate the quality of tuberculosis care offered by health providers in India. The overall goal of my research program is to use translational epidemiology and implementation science to support tuberculosis care and control, so that the products developed, knowledge and policies can translate into saved lives.Team Members
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Latest Publications
- Nafade, V., Sen, P., Arentz, M., Kadam, R., Bigio, J., Allen, L. N., Blandina, D. M., Bosire, S., Ferreira, J., Jha, S., John, O., Kalantri, S. P., Mwirigi, N., Faal-Omisore, M., Ugarte-Gil, C., Vijayan, S., Wangari, M.-C. & Pai, M. (2024). The value of diagnostic imaging for enhancing primary care in low- and middle-income countries. EClinicalMedicine, vol. 77, p. 102899.
- Sassi, A., Rosapep, L., Faleye, B. O., Baruwa, E., Johns, B., Kafi, M. A. H., Huria, L., Aguilera Vasquez, N., Daniels, B., Das, J., Anyaike, C., Chijioke-Akaniro, O., Pai, M., Oga-Omenka, C., Sassi, A., Rosapep, L., Faleye, B. O., Baruwa, E., Johns, B., Kafi, M. A. H., Huria, L., Aguilera Vasquez, N., Daniels, B., Das, J., Anyaike, C., Chijioke-Akaniro, O., Pai, M. & Oga-Omenka, C. (2024). Private sector tuberculosis care quality during the COVID-19 pandemic: a repeated cross-sectional standardised patients study of adherence to national TB guidelines in urban Nigeria. BMJ global health, vol. 9.
- Pai, M., Bandara, S. & Kyobutungi, C. (2024). Shifting power in global health will require leadership by the Global South and allyship by the Global North. Lancet (London, England).
- Widarna, R., Afifah, N., Djunaedy, H. A. K., Sassi, A., Vasquez, N. A., Oga-Omenka, C., Salindri, A. D., Lestari, B. W., Pai, M. & Alisjahbana, B. (2024). The shifting landscape of private healthcare providers before and during the COVID-19 pandemic: Lessons to strengthen the private sectors engagement for future pandemic and tuberculosis care. PLOS global public health, vol. 4, p. e0003112.
- Faust, L., Ranjan, A., Jha, N., Pai, M. & Huddart, S. (2024). Case fatality among people with drug-susceptible TB enrolled in a private health sector TB treatment support program in Bihar, India during the first year of the COVID-19 pandemic. PLOS global public health, vol. 4, p. e0003277.
- Pai, M., Gandra, S., Thapa, P. & Carmona, S. (2024). Tackling antimicrobial resistance: recognising the proposed five blind spots can accelerate progress. The Lancet. Microbe, p. 100968.
- Adetifa, I. M. & Pai, M. (2024). Mpox outbreaks in Africa-we must avert another failure of global solidarity. BMJ (Clinical research ed.), vol. 386, p. q1803.
- Tandan, M., Thapa, P., Bhandari, B., Gandra, S., Timalsina, D., Bohora, S., Thapaliya, S., Bhusal, A., Gore, G. C., Sheokand, S., Shukla, P., Joshi, C., Mudgal, N., Pai, M. & Sulis, G. (2024). Antibiotic dispensing practices among informal healthcare providers in low-income and middle-income countries: a scoping review protocol. BMJ open, vol. 14, p. e086164.
- Broger, T., Marx, F. M., Theron, G., Marais, B. J., Nicol, M. P., Kerkhoff, A. D., Nathavitharana, R., Huerga, H., Gupta-Wright, A., Kohli, M., Nichols, B. E., Muyoyeta, M., Meintjes, G., Ruhwald, M., Peeling, R. W., Pai, N. P., Pollock, N. R., Pai, M., Cattamanchi, A., Dowdy, D. W., Dewan, P. & Denkinger, C. M. (2024). Diagnostic yield as an important metric for the evaluation of novel tuberculosis tests: rationale and guidance for future research. The Lancet. Global health, vol. 12, p. e1184-e1191.
- Jhaveri, T. A., Jhaveri, D., Galivanche, A., Lubeck-Schricker, M., Voehler, D., Chung, M., Thekkur, P., Chadha, V., Nathavitharana, R., Kumar, A. M. V., Shewade, H. D., Powers, K., Mayer, K. H., Haberer, J. E., Bain, P., Pai, M., Satyanarayana, S. & Subbaraman, R. (2024). Barriers to engagement in the care cascade for tuberculosis disease in India: A systematic review of quantitative studies. PLoS medicine, vol. 21, p. e1004409.
See also
