Lab Information
Madhukar Pai (MD/PhD)
Senior ScientistCentre for Outcomes Research and Evaluation
Department of Epidemiology, Biostatistics and Occupational Health (McGill)
Research Profile
https://www.paitbgroup.org/
Keywords
Tuberculosis • diagnostics • epidemiology • global health • implementation researchResearch Interests
My research focuses on tuberculosis. It is a major threat to human health, with 9 million new cases and 1.5 million deaths every year. I have focused my career on improving tuberculosis diagnosis and care, with research that includes evaluating diagnostics tests that could eventually be part of country-level policies, implementation of tools and policies, and improving tuberculosis care for vulnerable populations in different countries worldwide. For example, I have compared the accuracy and usefulness of new tests that can diagnose tuberculosis in a few hours to conventional techniques which may require days before results are known. I am also conducting a study using mystery patients to evaluate the quality of tuberculosis care offered by health providers in India. The overall goal of my research program is to use translational epidemiology and implementation science to support tuberculosis care and control, so that the products developed, knowledge and policies can translate into saved lives.Team Members
| Name | Position |
|---|
Latest Publications
- Denkinger, C. M., Yerlikaya, S., Cattamanchi, A. & Pai, M. (2026). Near point-of-care molecular tests for tuberculosis: what will it take to realize their potential?. EClinicalMedicine, vol. 95, p. 103972.
- Zimmer, A. J., Espinoza-Lopez, P., Ravi, V., Sieberts, S. K., Abbasgholizadeh Rahimi, S., Pai, M., Ugarte-Gil, C. & Grandjean Lapierre, S. (2026). External validation of cough-based algorithms for pulmonary tuberculosis screening from the CODA TB DREAM challenge using cough data from Peru. Scientific reports.
- Kebede, Y., Ndlovu, N., Nabadda, S., Sawadogo, C., Fuller, D., Pai, M., Ashenafi, A., Vojnov, L., Kadam, R., Kallarakal, A., Jani, I., Mushavi, A., Jallow, F., Coulibaly, S. O., Baptiste, S., Ehrenkrantz, P., Mertz, C., Kang, G., De Lussigny, S., Ghadrshenas, A., Fleming, K., Kao, K., Williams, J., Van Germet, W., Kaiser, B., Gadde, R., Rodriguez, W., Fongwen, N., Mataka, A., Mashate, S., Bryant, J., Ondoa, P., Otieno, O., Kachuwaire, O., Maryogo-Robinson, L., Staley, S., Agarwal, N., Brodsky, S., Patil, A., Mesfin, M., Anupindi, R., Rupani, S., Mbulawa, M., Albert, H., Kohli, M., Pai, N., Loembe, M., Nyaruhirira, A., Titanji, B., Bhadelia, N., Desalegn, D., Mimbe, D., Ochieng, E., Mataranyika, M., Biscornet, L., Mulenga, N., Tsai, Y., Islam, R., Williams, F., Ndasi, J., Ntoumi, F., Lamorde, M., Vubil, A., Sultane, T., Pal, A., Magnet, S., Maggiore, P., Luo, R., Sayed, S., Shakoor, S., Umutesi, G., Domingo, G., Bitilinyu-Bangoh, J., Dieye, A., Otieno, C., Tamadea, L., Murenzi, G., Carter, J., Ocen, F., Capri, A., Schroeder, L., Wilson, M., Gerth-Guyette, E., Nsamba, D., Awinibuno, I., Odiabara, K., Kujinga, T., Rahman, F., Ndlovu, Z., Dumas, D., Sambe, N., Bansal, Y., Qin, Z. Z., Donoso-Bach, L., Estelle, R., Dlamini, S., Obiekea, C., Bradley, K. & Peter, T. (2026). The future of diagnostics in Africa. Nature medicine, vol. 32, p. 1623-1633.
- Oga-Omenka, C., Rabvukwa, A., Chijioke-Akaniro, O., Mwirigi, N. & Pai, M. (2026). Understanding where people with tuberculosis seek care to serve them better. Lancet (London, England), vol. 407, p. 1310-1313.
- Munyangaju, I., Carratalà-Castro, L., Osório, D., Bigio, J., Mateyo, K. J., Vonasek, B. J., Buonsenso, D., Bassat, Q., Serres-Créixams, X., Thierry-Chef, I., Garcia-Basteiro, A., Pai, M. & Lopez-Varela, E. (2026). A systematic review and meta-analysis of the diagnostic accuracy of ultrasound in the diagnosis of paediatric tuberculosis. Journal of tropical pediatrics, vol. 72.
- Zimmer, A. J., Ravi, V., Espinoza-Lopez, P., Kafentzis, G. P., Ravanelli, M., Abbasgholizadeh Rahimi, S., Pai, M., Ugarte-Gil, C. & Grandjean Lapierre, S. (2026). Cough acoustic analysis using artificial intelligence for COVID-19 detection: A comparative study of patient cohorts from Lima, Peru and Montreal, Canada. Annals of epidemiology, vol. 118, p. 110076.
- Pai, M. (2026). From Thomas Mann to John Green, how authors and books shape our understanding of TB. IJTLD open, vol. 3, p. 118-121.
- Coleman, M., Calderwood, C. J., Magee, S., Underwood, F., Kunor, T., Timire, C., Velen, K., MacLean, E. L., Pai, M., Khan, P. Y., Bhargava, A., Bhargava, M., Martinez, L., Kranzer, K., Bernays, S. & Marais, B. J. (2026). The tuberculogenic environment. The Lancet. Global health, vol. 14, p. e444-e454.
- Barrett, R., Qin, Z. Z., Kohli, M. & Pai, M. (2026). AI-powered digital stethoscopes: A new opportunity in tuberculosis screening?. Med (New York, N.Y.), vol. 7, p. 100964.
- Gaeddert, M., Papadopoulou, P., Habbes, J., Niederegger, T., Schik, L., Meister, J., Grilli, M., Beecroft, A., Kohli, M., Pai, M., Denkinger, C. M., Marx, F. M. & Gupta-Wright, A. (2025). Sputum scarcity among adolescents and adults with presumptive tuberculosis: a systematic review and meta-analysis. medRxiv : the preprint server for health sciences.
See also
