Lab Information

Madhukar Pai (MD/PhD)

Senior Scientist
Centre for Outcomes Research and Evaluation
Department of Epidemiology, Biostatistics and Occupational Health (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 0%
 Epidemiology: 100%
 Evaluation: 0%
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Tuberculosis • diagnostics • epidemiology • global health • implementation research

Research Interests

My research focuses on tuberculosis. It is a major threat to human health, with 9 million new cases and 1.5 million deaths every year. I have focused my career on improving tuberculosis diagnosis and care, with research that includes evaluating diagnostics tests that could eventually be part of country-level policies, implementation of tools and policies, and improving tuberculosis care for vulnerable populations in different countries worldwide. For example, I have compared the accuracy and usefulness of new tests that can diagnose tuberculosis in a few hours to conventional techniques which may require days before results are known. I am also conducting a study using mystery patients to evaluate the quality of tuberculosis care offered by health providers in India. The overall goal of my research program is to use translational epidemiology and implementation science to support tuberculosis care and control, so that the products developed, knowledge and policies can translate into saved lives.

Team Members

Name Position

Latest Publications

  1. Bigio, J., Aquilera Vasquez, N., Huria, L., Pande, T., Creswell, J., Ananthakrishnan, R., Bimba, J. S., Cuevas, L. E., Vo, L., Bakker, M. I., Rahman, M. T. & Pai, M. (2022). Engaging pharmacies in tuberculosis control: operational lessons from 19 case detection interventions in high-burden countries. BMJ global health, vol. 7.
  2. Dheda, K., Perumal, T., Moultrie, H., Perumal, R., Esmail, A., Scott, A. J., Udwadia, Z., Chang, K. C., Peter, J., Pooran, A., von Delft, A., von Delft, D., Martinson, N., Loveday, M., Charalambous, S., Kachingwe, E., Jassat, W., Cohen, C., Tempia, S., Fennelly, K. & Pai, M. (2022). The intersecting pandemics of tuberculosis and COVID-19: population-level and patient-level impact, clinical presentation, and corrective interventions. The Lancet. Respiratory medicine.
  3. Yamey, G., Garcia, P., Hassan, F., Mao, W., McDade, K. K., Pai, M., Saha, S., Schellekens, P., Taylor, A. & Udayakumar, K. (2022). It is not too late to achieve global covid-19 vaccine equity. BMJ (Clinical research ed.), vol. 376, p. e070650.
  4. Pai, M. & Zar, H. J. (2022). Childhood Tuberculosis - Time for Shorter and Differentiated Treatment. The New England journal of medicine, vol. 386, p. 988-989.
  5. MacLean, E. L., Villa-Castillo, L., Ruhwald, M., Ugarte-Gil, C. & Pai, M. (2022). Integrated testing for TB and COVID-19. Med (New York, N.Y.), vol. 3, p. 162-166.
  6. Salomon, A., Boffa, J., Moyo, S., Chikovore, J., Sulis, G., Daniels, B., Kwan, A., Mkhombo, T., Wu, S., Pai, M. & Daftary, A. (2022). Prescribing practices for presumptive TB among private general practitioners in South Africa: a cross-sectional, standardised patient study. BMJ global health, vol. 7.
  7. Lancione, S., Alvarez, J. V., Alsdurf, H., Pai, M. & Zwerling, A. A. (2022). Tracking changes in national BCG vaccination policies and practices using the BCG World Atlas. BMJ global health, vol. 7.
  8. Pai, M., Kasaeva, T. & Swaminathan, S. (2022). Covid-19's Devastating Effect on Tuberculosis Care - A Path to Recovery. The New England journal of medicine, vol. 386, p. 1490-1493.
  9. Das, V., Daniels, B., Kwan, A., Saria, V., Das, R., Pai, M. & Das, J. (2021). Simulated patients and their reality: An inquiry into theory and method. Social science & medicine (1982), p. 114571.
  10. Huddart, S., Ingawale, P., Edwin, J., Jondhale, V., Pai, M., Benedetti, A., Shah, D. & Vijayan, S. (2021). TB case fatality and recurrence in a private sector cohort in Mumbai, India. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, vol. 25, p. 738-746.
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