Dr. Kevin Kain

Canada Research Chair in Molecular Parasitology.
Professor of Medicine, University of Toronto.

Science Director
Tropical Disease Unit, Toronto General Hospital – University Health Network.

Director
SA Rotman Laboratories, Sandra Rotman Centre for Global Health.

Dr. Kain is a Professor of Medicine, University of Toronto; Director, SAR Laboratories, Sandra Rotman Centre for Global Health; Science Director, Tropical Disease Unit at Toronto General Hospital; and holds a Canada Research Chair (Tier I). Dr. Kain’s research career began with Walter Reed Army Institute of Research (WRAIR) working on the 1st generation of malaria vaccines including the 1st field trials (Thai-Cambodian border). His efforts now focus on the pathobiology of life-threatening infections in order to develop new diagnostics and interventions to improve outcome. Dr Kain’s efforts are also focused on global maternal –child health, gender equality, knowledge sharing and education, including the transfer of appropriate technologies and the training of scientists in the developing world, enabling and empowering them to address their own problems in a sustainable fashion. He operates multiple global research projects including projects in Mozambique, Malawi, Uganda, Tanzania, Colombia, Thailand, and Vietnam.

In December 2017 he was invited to speak at the White House on the emergence of an alarming multi-drug resistant strain of malaria and it’s implications for US foreign policy and US multi-nationals. He has also served as a consultant to many organizations including the Gates Foundation, Red Cross, PATH, US Department of Defense, and the CDC.

Visit his website for more information. 


Dr. Sharon Walmsley

University health network, University of Toronto
Toronto General Hospital Research Institute
University of Toronto

She is the Director of the Immunodeficiency Clinic, Toronto Hospital, University Health Network and a Professor, University of Toronto Department of Medicine.  She is a Senior Scientist at the Toronto General Hospital Research Institute and the Co- Chair of the CIHR- Canadian HIV Trials Network. She is actively involved in the design, conduct and analysis of many clinical trials, including trials in HIV therapy; prophylaxis and treatment of opportunistic infections, and management of the complications of treatment. She has had a longstanding and strong interest in gender differences in HIV in women.  She has been an advocate of gender specific analysis of clinical trials of antiretroviral therapy. She holds numerous peer-reviewed publications and research awards related to clinical trials in HIV.  She is the recipient of a Chair in HIV Clinical Management and Aging from the Ontario HIV Treatment Network.  In June 2017, she was appointed as a Member of the Order of Canada contributions in HIV Research especially related to advancing therapy for women, and mentoring young female investigators.

Visit his website for more information. 


Dr. Charu Kaushic

Professor
Department of Pathology and Mol. Medicine
McMaster Immunology Research Center,
McMaster University

Charu Kaushic was appointed as the Scientific Director of the Institute of Infection and Immunity, starting July 1, 2018. Dr. Kaushic is a full Professor in the Department of Pathology and Molecular Medicine.  She is a member of the McMaster Immunology Research Centre (MIRC) and the Michael De Groote Institute of Infectious Disease Research (IIDR) and an Associate Faculty in Department of Obstetrics and Gynaecology and Department of Biochemistry and Biomedical Sciences.

Dr. Kaushic obtained her PhD at National Institute of Immunology in New Delhi, India followed by post-doctoral work in the area of mucosal immunity at Dartmouth Medical School with Dr. Charles Wira. She joined as faculty in McMaster University in 2002, where she has done extensive teaching and training and built an interdisciplinary research program for last 15 years. Her research interest is women’s reproductive health, specifically basic, clinical and translational research examining susceptibility and immune responses to sexually transmitted viruses, HIV-1 and HSV-2. Areas of special focus in her research are effect of female sex hormones, co-infections and microbiome on mucosal immunity to viral STIs. Charu has special interest in public education, especially on women’s reproductive health issues and has long term collaborations with community research organizations.

Dr. Kaushic’s research has been funded by CIHR, CFI, CANFAR and OHTN. Charu has received numerous national and international awards including a Rockefeller post-doctoral fellowship, CIHR New Investigator Award, OHTN Research Scholar award, OHTN Research Chair award and recently an American Journal of Reproductive Immunology Research Excellence Award. She has served on a number of scientific panels including CIHR, NIH and is a member of CIHR College of Reviewers, was a research representative on OHTN Board of Directors and Secretary of the American Society of Reproductive Immunology.

Visit his website for more information. 


Dr. Katherine A. Siminovitch

Senior Scientist
Mount Sinai Hospital/University Health Network

Dr. Siminovitch is a Professor of Medicine at the University of Toronto, holds an MD from the University of Toronto, and is a Fellow of the Royal College of Physicians and Surgeons of Canada in Internal Medicine and Rheumatology. She serves as the Director of the Fred A. Litwin Family Centre of Genetic Medicine at the University Health Network (UHN) and Mount Sinai Hospital and also founded and directs the UHN/MSH Clinical Genomics Centre.

Dr. Siminovitch’s research programme is directed at identifying the molecular factors which regulate normal immune responses and which, when disrupted, result in immune deficiency or autoimmune diseases such as rheumatoid arthritis, granulomatosis with polyangiitis and other autoimmune inflammatory conditions.  Using both basic research tools and clinical sample sets, Dr. Siminovitch has made many seminal contributions to defining the genetic variants predisposing to these diseases and the molecular pathways which couple these lesions to cell dysfunction and disease. Over the past few years, she has initiated a personalized healthcare platform at MSH, aimed at integrating advanced molecular information with clinical data so as to identify gene variants influencing disease risk and genetic/immunologic predictors of disease course and treatment responses. 

Dr. Siminovitch has been elected as a Fellow of the Royal Society of Canada, the American Association of Physicians and the Canadian Academy of Health Sciences and she holds a Canada Research Chair in Immunogenomics. 


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Upcoming Events

Latest IDIGH Publications

  1. Slim, Z., Moura, C. S., Bernatsky, S. & Rahme, E.
    (2019)
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    Care quality for rheumatoid arthritis patients in Quebec
    .
    International journal of rheumatic diseases
  2. Legge, A., Kirkland, S., Rockwood, K., Andreou, P., Bae, S.-C., Gordon, C., Romero-Diaz, J., Sanchez-Guerrero, J., Wallace, D. J., Bernatsky, S., Clarke, A. E., Merrill, J. T., Ginzler, E. M., Fortin, P., Gladman, D. D., Urowitz, M. B., Bruce, I. N., Isenberg, D. A., Rahman, A., Alarcón, G. S., Petri, M., Khamashta, M. A., Dooley, M. A., Ramsey-Goldman, R., Manzi, S., Zoma, A. A., Aranow, C., Mackay, M., Ruiz-Irastorza, G., Lim, S. S., Inanc, M., van Vollenhoven, R. F., Jonsen, A., Nived, O., Ramos-Casals, M., Kamen, D. L., Kalunian, K. C., Jacobsen, S., Peschken, C. A., Askanase, A. & Hanly, J. G.
    (2019)
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    Construction of a frailty index as a novel health measure in systemic lupus erythematosus
    .
    The Journal of rheumatology
  3. de Pokomandy, A., Burchell, A. N., Salters, K., Ding, E., O'Brien, N., Bakombo, D. M., Proulx-Boucher, K., Boucoiran, I., Pick, N., Ogilvie, G., Loutfy, M., Kaida, A. & CHIWOS Research Team.
    (2019)
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    Cervical cancer screening among women living with HIV: a cross-sectional study using the baseline questionnaire data from the Canadian HIV Women's Sexual and Reproductive Health Cohort Study (CHIWOS)
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    CMAJ open
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    vol
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    7
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    p
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    E217-E226
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  4. MacLean, E., Broger, T., Yerlikaya, S., Fernandez-Carballo, B. L., Pai, M. & Denkinger, C. M.
    (2019)
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    Author Correction: A systematic review of biomarkers to detect active tuberculosis
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    Nature microbiology
  5. Freeman, M. C., Akogun, O., Belizario, V., Brooker, S. J., Gyorkos, T. W., Imtiaz, R., Krolewiecki, A., Lee, S., Matendechero, S. H., Pullan, R. L. & Utzinger, J.
    (2019)
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    Challenges and opportunities for control and elimination of soil-transmitted helminth infection beyond 2020
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    PLoS neglected tropical diseases
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    vol
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    13
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    p
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    e0007201
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More publications