Lab Information

Dr. Todd Lee

Centre for Innovative Medicine
Department of Medicine (McGill)

Research Profile

 Fundamental: 30%
 Clinical: 40%
 Epidemiology: 0%
 Evaluation: 30%
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Quality improvement • patient safety • high value healthcare • antibiotic stewardship • polypharmacy

Research Interests

My research focuses on conducting randomized clinical trials designed to improve the treatment of infectious diseases (e.g., C. difficile, COVID-19, S. aureus, Gram-Negative infections) and to innovate in the domains of care of complex hospitalized patients, care of older adults with polypharmacy, and stewardship of healthcare resources (e.g., testing, medications).

Team Members

Name Position
Chandralingam, Manoja Junior Assistant
Elsayed, Sarah Research Assistant
Leite, Gleice Research Assistant
Moran, Kristen Junior Assistant
Mefanche, Liliane Research Assistant
Kamozin, Andrey Programmer
Kim, Yejim Interviewer
Smyth, Louisa Data Entry Clerk

Latest Publications

  1. Fw, H., Tc, L., Dt, A., R, L. & K, H. (2021). Is convalescent plasma futile in COVID-19? A Bayesian re-analysis of the RECOVERY randomised controlled trial. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
  2. Iatan, I., Lee, T. C. & McDonald, E. G. (2021). Tenofovir-induced osteomalacia with hypophosphataemia. BMJ case reports, vol. 14.
  3. Demir, K. K., Butler-Laporte, G., Del Corpo, O., Ekmekjian, T., Sheppard, D. C., Lee, T. C. & Cheng, M. P. (2021). Comparative effectiveness of amphotericin B, azoles and echinocandins in the treatment of candidemia and invasive candidiasis: A systematic review and network meta-analysis. Mycoses.
  4. Cheng, M. P., Cau, A., Lee, T. C., Brodie, D., Slutsky, A., Marshall, J., Murthy, S., Lee, T., Singer, J., Demir, K. K., Boyd, J., Ohm, H., Maslove, D., Goffi, A., Bogoch, I. I., Sweet, D. D., Walley, K. R., Russell, J. A. & Angiotensin Receptor Blocker Coronavirus Study (ARBs) CORONA I (2021). Acute Cardiac Injury in Coronavirus Disease 2019 and Other Viral Infections-A Systematic Review and Meta-Analysis. Critical care medicine.
  5. Lee, T., Cau, A., Cheng, M. P., Levin, A., Lee, T. C., Vinh, D. C., Lamontagne, F., Singer, J., Walley, K. R., Murthy, S., Patrick, D., Rewa, O. G., Winston, B. W., Marshall, J., Boyd, J., Tran, K., Kalil, A., McCuloh, R., Fowler, R., Luther, J. M., Russell, J. A. & ARBs CORONA (2021). ANGIOTENSIN RECEPTOR BLOCKERS AND ANGIOTENSIN CONVERTING ENZYME INHIBITORS IN COVID-19 -META-ANALYSIS/META-REGRESSION ADJUSTED FOR CONFOUNDING FACTORS. CJC open.
  6. Demir, K. K., McDonald, E. G., de L'Étoile-Morel, S., Schweitzer, L., Butler-Laporte, G., Cheng, M. P. & Lee, T. C. (2021). Handheld infrared thermometer to evaluate cellulitis: the HI-TEC study. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
  7. Dionne, B. & Lee, T. C. (2021). Probable immortal time bias in comparison of daptomycin and vancomycin for MRSA bloodstream infections. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
  8. Murthy, S., Archambault, P. M., Atique, A., Carrier, F. M., Cheng, M. P., Codan, C., Daneman, N., Dechert, W., Douglas, S., Fiest, K. M., Fowler, R., Goco, G., Gu, Y., Guerguerian, A.-M., Hall, R., Hsu, J. M., Joffe, A., Jouvet, P., Kelly, L., Kho, M. E., Kruisselbrink, R. J., Kumar, D., Kutsogiannis, D. J., Lamontagne, F., Lee, T. C., Menon, K., O'Grady, H., O'Hearn, K., Ovakim, D. H., Pharand, S. G., Pitre, T., Reel, R., Reeve, B., Rewa, O., Richardson, D., Rishu, A., Sandhu, G., Sarfo-Mensah, S., Shadowitz, E., Sligl, W., Solomon, J., Stelfox, H. T., Swanson, A., Tessier-Grenier, H., Tsang, J. L. Y., Wood, G. & SPRINT-SARI Canada Investigators and the Canadian Critical Care Trials Group (2021). Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study. CMAJ open, vol. 9, p. E181-E188.
  9. Murthy, S. & Lee, T. C. (2021). IL-6 blockade for COVID-19: a global scientific call to arms. The Lancet. Respiratory medicine, vol. 9, p. 438-440.
  10. Eljaaly, K., Bidell, M. R., Gandhi, R. G., Alshehri, S., Enani, M. A., Al-Jedai, A. & Lee, T. C. (2021). Colistin Nephrotoxicity: Meta-Analysis of Randomized Controlled Trials. Open forum infectious diseases, vol. 8, p. ofab026.
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