Lab Information

Dr. Sasha Bernatsky

Senior Scientist
Centre for Outcomes Research and Evaluation
Department of Medicine (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 0%
 Epidemiology: 100%
 Evaluation: 0%
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 3F.51

Keywords

Outcomes in rheumatic diseases • pharmacoepidemiology • air pollution’s effects on health • systemic lupus erythematosus

Research Interests

Dr. Sasha Bernatsky is a James McGill Professor of Medicine at McGill University (divisions of rheumatology and clinical epidemiology), and senior scientist within the Centre for Health Outcomes Research at the Research Institute of the McGill University Health Centre, the Infectious Diseases and Immunity in Global Health Program, and McGill’s Epidemiology and Biostatistics Department. She is nominated PI of CAN-AIM (CAnadian Network for Advanced Interdisciplinary Methods for comparative effectiveness research), a pan-Canadian group funded by the Drug Safety and Effectiveness Network (DSEN), a collaboration between CIHR, Health Canada, and other stakeholders. Working with Health Canada’s Marketed Health Products Directorate and other regulators, CAN-AIM studies high-priority drug safety and effectiveness topics, making essential contributions to Canada’s research capacity. She also mentors within CIHR’s Drug Safety and Effectiveness Cross-Disciplinary Training Program, preparing future leaders in this field.

Working with the SLE International Collaborating Clinics and the Canadian Network for Improved Outcomes in SLE, Dr. Bernatsky leads international initiatives including assessments of malignancy in SLE, and personalizing approaches to hydroxychloroquine therapy. She co-founded several collaborative networks, including the Canadian Rheumatology Administrative Data Network (CANRAD), focussing on optimal use of administrative data for research and surveillance. Studying rheumatic disease patterns with administrative data from across Canada, she contributed greatly to Public Health Agency of Canada’s work on rheumatic disease case validation, and helped the Canadian Institute for Health Information refine case definitions for federal research and surveillance. Affiliated with the McGill Environmental Epidemiology Research Group and the Canadian Urban Environmental Health Research Consortium, she pioneered studies of air pollution and systemic autoimmune rheumatic diseases.


Team Members

Name Position
Lukusa, Luck Data Analyst
Lee, Jennifer Project Manager
Zhao, Naizhuo Research Associate
Moura, Cristiano Research Associate
Kaddoura, Rima PhD Student
Neville, Autumn Research Coordinator

Latest Publications

  1. Zeng, Y., Zhao, K., Oros Klein, K., Shao, X., Fritzler, M. J., Hudson, M., Colmegna, I., Pastinen, T., Bernatsky, S. & Greenwood, C. M. T. (2021). Thousands of CpGs Show DNA Methylation Differences in ACPA-Positive Individuals. Genes, vol. 12.
  2. Zheng, B., Soares de Moura, C., Machado, M., Pineau, C. A., Curtis, J. R., Vinet, E. & Bernatsky, S. (2021). Association between chronic obstructive pulmonary disease, smoking, and interstitial lung disease onset in rheumatoid arthritis. Clinical and experimental rheumatology.
  3. Eder, L., Croxford, R., Drucker, A. M., Mendel, A., Kuriya, B., Touma, Z., Johnson, S. R., Cook, R., Bernatsky, S., Haroon, N. & Widdifield, J. (2021). Understanding COVID-19 Risk in Patients with Immune Mediated Inflammatory Diseases: A Population-based analysis of SARS-CoV-2 Testing. Arthritis care & research.
  4. Machado, M. A. A., Moura, C. S., Abrahamowicz, M., Ward, B. J., Pilote, L. & Bernatsky, S. (2021). Relative effectiveness of influenza vaccines in elderly persons in the United States, 2012/2013-2017/2018 seasons. NPJ vaccines, vol. 6, p. 108.
  5. Lambert-Fliszar, F., Bernatsky, S., Kalache, F., Grenier, L.-P., Pineau, C. A. & Vinet, E. (2021). Personalised therapy during preconception and gestation in SLE: usefulness of 6-mercaptopurine metabolite levelswith azathioprine. Lupus science & medicine, vol. 8.
  6. Bérard, A., Sheehy, O., Zhao, J.-P., Vinet, E., Quach, C. & Bernatsky, S. (2021). Chloroquine and Hydroxychloroquine Use During Pregnancy and the Risk of Adverse Pregnancy Outcomes Using Real-World Evidence. Frontiers in pharmacology, vol. 12, p. 722511.
  7. Zhao, N. & Bernatsky, S. (2021). Is air pollution linked with poor response to biologics?. Nature reviews. Rheumatology, vol. 17, p. 583-584.
  8. Hazlewood, G. S., Bombardier, C., Li, X., Movahedi, M., Choquette, D., Coupal, L., Bykerk, V., Schieir, O., Mosher, D., Marshall, D. A., Bernatsky, S., Spencer, N., Richards, D. P., Proulx, L., Barber, C. E. H. & OBRI, RHUMADATA®, CATCH investigators and The Rheum4U Team (2021). Heterogeneity in patient characteristics and differences in treatment across four Canadian rheumatoid arthritis cohorts. The Journal of rheumatology.
  9. Hoa, S., Bernatsky, S., Baron, M., Proudman, S., Stevens, W., Sahhar, J., Wang, M., Steele, R. J., Canadian Scleroderma Research Group (CSRG), Australian Scleroderma Interest Group (ASIG), Nikpour, M. & Hudson, M. (2021). ASSOCIATION BETWEEN IMMUNOSUPPRESSIVE THERAPY AND INCIDENT RISK OF INTERSTITIAL LUNG DISEASE IN SYSTEMIC SCLEROSIS. Chest.
  10. Hanly, J. G., Gordon, C., Bae, S.-C., Romero-Diaz, J., Sanchez-Guerrero, J., Bernatsky, S., Clarke, A. E., Wallace, D. J., Isenberg, D. A., Rahman, A., Merrill, J. T., Fortin, P. R., Gladman, D. D., Urowitz, M. B., Bruce, I. N., Petri, M., Ginzler, E. M., Dooley, M. A., Ramsey-Goldman, R., Manzi, S., Jonsen, A., Alarcón, G. S., van Vollenhoven, R. F., Aranow, C., Mackay, M., Ruiz-Irastorza, G., Lim, S. S., Inanc, M., Kalunian, K. C., Jacobsen, S., Peschken, C. A., Kamen, D. L., Askanase, A. & Farewell, V. (2021). Neuropsychiatric Events in Systemic Lupus Erythematosus. Arthritis & rheumatology (Hoboken, N.J.).
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