Lab Information

Dr. Madhukar Pai

Senior Scientist
Centre for Outcomes Research and Evaluation
Department of Epidemiology, Biostatistics and Occupational Health (McGill)

Research Profile

 Fundamental: 0%
 Clinical: 0%
 Epidemiology: 100%
 Evaluation: 0%
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Tuberculosis • diagnostics • epidemiology • global health • implementation research

Research Interests

My research focuses on tuberculosis. It is a major threat to human health, with 9 million new cases and 1.5 million deaths every year. I have focused my career on improving tuberculosis diagnosis and care, with research that includes evaluating diagnostics tests that could eventually be part of country-level policies, implementation of tools and policies, and improving tuberculosis care for vulnerable populations in different countries worldwide. For example, I have compared the accuracy and usefulness of new tests that can diagnose tuberculosis in a few hours to conventional techniques which may require days before results are known. I am also conducting a study using mystery patients to evaluate the quality of tuberculosis care offered by health providers in India. The overall goal of my research program is to use translational epidemiology and implementation science to support tuberculosis care and control, so that the products developed, knowledge and policies can translate into saved lives.

Team Members

Name Position
Vadnais, Caroline Manager (Research)
Svadzian, Anita PhD Student
Huddart, Sophie PhD Student
Kohli, Mikashmi Postdoc
Maclean, Emily PhD Student
Sen, Paulami MSc Student
Sulis, Giorgia PhD Student
Faust, Lena PhD Student
Heitkamp, Petra Project Manager
Omenka, Charity Program Officer
Aguilera Vasquez, Nathaly Program Officer
Bigio, Jacob Research Associate
Huria, Lavanya Junior Assistant

Latest Publications

  1. Bigio, J., Kohli, M., Klinton, J. S., MacLean, E., Gore, G., Small, P. M., Ruhwald, M., Weber, S. F., Jha, S. & Pai, M. (2021). Diagnostic accuracy of point-of-care ultrasound for pulmonary tuberculosis: A systematic review. PloS one, vol. 16, p. e0251236.
  2. Huddart, S., Singh, M., Jha, N., Benedetti, A. & Pai, M. (2021). Case fatality and recurrent tuberculosis among patients managed in the private sector: A cohort study in Patna, India. PloS one, vol. 16, p. e0249225.
  3. Abimbola, S. & Pai, M. (2021). Undoing supremacy in global health will require more than decolonisation - Authors' reply. Lancet (London, England), vol. 397, p. 1058-1059.
  4. Zifodya, J. S., Kreniske, J. S., Schiller, I., Kohli, M., Dendukuri, N., Schumacher, S. G., Ochodo, E. A., Haraka, F., Zwerling, A. A., Pai, M., Steingart, K. R. & Horne, D. J. (2021). Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis. The Cochrane database of systematic reviews, vol. 2, p. CD009593.
  5. Oga-Omenka, C., Tseja-Akinrin, A., Boffa, J., Heitkamp, P., Pai, M. & Zarowsky, C. (2020). Commentary: Lessons from the COVID-19 global health response to inform TB case finding. Healthcare (Amsterdam, Netherlands), vol. 9, p. 100487.
  6. MacLean, E., Bigio, J., Singh, U., Klinton, J. S. & Pai, M. (2021). Global tuberculosis awards must do better with equity, diversity, and inclusion. Lancet (London, England), vol. 397, p. 192-193.
  7. Pande, T., Vasquez, N. A., Cazabon, D., Creswell, J., Brouwer, M., Ramis, O., Stevens, R. H., Ananthakrishnan, R., Qayyum, S., Alphonsus, C., Oga-Omenka, C., Nafade, V., Sen, P. & Pai, M. (2020). Finding the missing millions: lessons from 10 active case finding interventions in high tuberculosis burden countries. BMJ global health, vol. 5.
  8. Abimbola, S. & Pai, M. (2020). Will global health survive its decolonisation?. Lancet (London, England), vol. 396, p. 1627-1628.
  9. Shrinivasan, R., Rane, S. & Pai, M. (2020). India's syndemic of tuberculosis and COVID-19. BMJ global health, vol. 5.
  10. Pai, M. (2020). Author Correction: Covidization of research: what are the risks?. Nature medicine, vol. 26, p. 1801.
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