Lab Information

Dr. Jean-Pierre Routy

Senior Scientist
Centre for Translational Biology
Department of Medicine (McGill)

Research Profile

 Fundamental: 50%
 Clinical: 50%
 Epidemiology: 0%
 Evaluation: 0%
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 E03.5157 (modules S, T, U, V) /  #76487, #32600, #32625
 E03.5367 (modules A, B) /  #32307


HIV • vaccine • lymphoma • T cells • cytokines

Research Interests

My research focuses on HIV pathogenesis aiming at finding an HIV cure. Improving knowledge in immune tolerance in cancer and in immune privileged sites (central nervous system, testis) will be key to develop strategy to conquer cancers and auto-immune diseases.

Team Members

Name Position
Massicotte, Angie Research Coordinator
Isnard, Stephane Postdoc
Espaldon, Reynan Research Coordinator
Espaldon, Eshel Laboratory Technician
Pineda, Rhyan Research Coordinator
Girouard, Josée Research Nurse
Fombuena, Brandon Laboratory Technician
LIn, John Laboratory Technician
Ouyang, Jing Visiting Professor
Lovi, Cezar Research Coordinator
Peng, Xiaorong Visiting Scholar

Latest Publications

  1. El-Far, M., Durand, M., Turcotte, I., Larouche-Anctil, E., Sylla, M., Zaidan, S., Chartrand-Lefebvre, C., Bunet, R., Ramani, H., Sadouni, M., Boldeanu, I., Chamberland, A., Lesage, S., Baril, J.-G., Trottier, B., Thomas, R., Gonzalez, E., Filali-Mouhim, A., Goulet, J.-P., Martinson, J. A., Kassaye, S., Karim, R., Kizer, J. R., French, A. L., Gange, S. J., Ancuta, P., Routy, J.-P., Hanna, D. B., Kaplan, R. C., Chomont, N., Landay, A. L. & Tremblay, C. L. (2021). Upregulated IL-32 Expression And Reduced Gut Short Chain Fatty Acid Caproic Acid in People Living With HIV With Subclinical Atherosclerosis. Frontiers in immunology, vol. 12, p. 664371.
  2. Vaillancourt, M., Hubert, A., Subra, C., Boucher, J., Bazié, W. W., Vitry, J., Berrazouane, S., Routy, J.-P., Trottier, S., Tremblay, C., Jenabian, M.-A., Benmoussa, A., Provost, P., Tessier, P. A. & Gilbert, C. (2021). Velocity Gradient Separation Reveals a New Extracellular Vesicle Population Enriched in miR-155 and Mitochondrial DNA. Pathogens (Basel, Switzerland), vol. 10.
  3. Bazié, W. W., Goyer, B., Boucher, J., Zhang, Y., Planas, D., Chatterjee, D., Routy, J.-P., Alary, M., Ancuta, P. & Gilbert, C. (2021). Diurnal Variation of Plasma Extracellular Vesicle Is Disrupted in People Living with HIV. Pathogens (Basel, Switzerland), vol. 10.
  4. Isnard, S., Lin, J., Bu, S., Fombuena, B., Royston, L. & Routy, J.-P. (2021). Gut Leakage of Fungal-Related Products: Turning Up the Heat for HIV Infection. Frontiers in immunology, vol. 12, p. 656414.
  5. Brenner, B. G., Oliveira, M., Ibanescu, R.-I., Routy, J.-P. & Thomas, R. (2021). Cell culture selections reveal favourable drug resistance profiles for doravirine and islatravir. The Journal of antimicrobial chemotherapy.
  6. Fehr, D., Lebouché, B., Ruppenthal, L., Brownc, M., Obasc, N., Bourbonnière, E., Girouard, J., Massicotte, A., Jenabian, M.-A., Almomen, A.-A., Frenette, C., de Pokomandy, A., Cox, J., Giannakis, A., Cheng, M., Kronfli, N., Tsoukas, C., Zahedi, N., Szabo, J., Dehghani, K., Brouillette, M.-J., Falutz, J., Turner, H., Hamel, A., Duchesneau, C., Lanthier-Brun, J., Klein, M., Routy, J.-P. & Costiniuk, C. T. (2021). Characterization of people living with HIV in a Montreal-based tertiary care center with COVID-19 during the first wave of the pandemic. AIDS care, p. 1-7.
  7. Recordon-Pinson, P., Gosselin, A., Ancuta, P., Routy, J.-P. & Fleury, H. (2021). Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in two patients under antiretroviral therapy. Gut pathogens, vol. 13, p. 20.
  8. Chu, D., Schuster, T., Lessard, D., Mate, K., Engler, K., Ma, Y., Abulkhir, A., Arora, A., Long, S., de Pokomandy, A., Lacombe, K., Rougier, H., Cox, J., Kronfli, N., Hijal, T., Kildea, J., Routy, J.-P., Asselah, J. & Lebouché, B. (2021). Acceptability of a Patient Portal (Opal) in HIV Clinical Care: A Feasibility Study. Journal of personalized medicine, vol. 11.
  9. Peng, X., Isnard, S., Lin, J., Fombuena, B., Bessissow, T., Chomont, N. & Routy, J.-P. (2021). Differences in HIV burden in the inflamed and non-inflamed colon from a person living with HIV and ulcerative colitis. Journal of virus eradication, vol. 7, p. 100033.
  10. Planas, D., Pagliuzza, A., Ponte, R., Fert, A., Marchand, L. R., Massanella, M., Gosselin, A., Mehraj, V., Dupuy, F. P., Isnard, S., Goulet, J.-P., Lesage, S., Cohen, E. A., Ghali, M. P., Angel, J. B., Chomont, N., Routy, J.-P. & Ancuta, P. (2021). LILAC pilot study: Effects of metformin on mTOR activation and HIV reservoir persistence during antiretroviral therapy. EBioMedicine, vol. 65, p. 103270.
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