The new state-of-the-art MUHC, photo by Dr. Jing Liu
The new state-of-the-art MUHC, photo by Dr. Jing Liu

The IDIGH program is comprised of fundamental research scientists and clinicians in four groups (please see details below the overview diagram), who jointly tackle infectious and immune-mediated diseases of global importance. Click IDIGH Research Keywords for a snapshot of our members’ research interest.

  1. Centre for Translational Biology (CTB)
  2. Centre of Outcomes Research and Evaluation (CORE)
  3. Clinical
  4. McGill University Campus-based

Centre for Translational Biology (CTB) Members 

Photo by Dr. M. Lee (Dr. D. Sheppard lab)
Photo by Dr. M. Lee (Dr. D. Sheppard lab)

(Click Research at CTB for the research focuses):

Currently, the IDIGH CTB group consists of 20 research laboratories, with more than 120 full-time researchers, trainees and highly specialized research professionals.  All laboratories are located on E3 and E2 levels of the Research Institute of McGill University Health Centre (RI-MUHC), at the new state-of-the-art MUHC Glen campus that opened in the spring of 2015. Research conducted by IDIGH CTB laboratories is highly interdisciplinary and multidisciplinary and focused on five major themes of global health research. IDIGH CTB researchers have a strong track record of intra-IDIGH collaborations but also work with research groups outside IDIGH both nationally and internationally.  A major strength of research by IDIGH CTB groups is the close vicinity to the clinical facilities at the new MUHC Glen campus and the proximity to the health outcome/epidemiology component of IDIGH.  The synergistic interaction of basic biomedical, clinical and epidemiological research provides the framework for conducting work with high translational impact.

The researchers of CTB

  1. Dr. Marcel Behr

    Appointment

    Senior Scientist

    Keywords

    Tuberculosis
     Molecular Epidemiology
     Bacille Calmette‑Guérin (BCG) Vaccine
     Innnate Immunity
     Crohn's Disease
  2. Dr. Nicole Bernard

    Appointment

    Scientist

    Keywords

    HIV/AIDS
     Cellular Immunology
     Correlates Of Protection
     T Cells
     NK Cells
  3. Dr. Inés Colmegna

    Appointment

    Scientist

    Keywords

    Immunology
     Arthritis
     Aging
     Stem Cells
  4. Dr. Cecilia Costiniuk

    Appointment

    Junior Scientist

    Keywords

    HIV
     HIV Reservoirs
     Chronic Lung Disease
     Pulmonary Inflammation
     Pulmonary Immunity
  5. Dr. John Di Battista

    Appointment

    Senior Scientist

    Keywords

    Signaling
     Genetics
     Proteomics
     G Protein‑coupled Receptors (GPCRs)
     Inflammation
  6. Dr. Momar Ndao

    Appointment

    Scientist

    Keywords

    Infectious Diseases
     Parastic Infections
     Host‑parasite Interactions
  7. Dr. Martin Olivier

    Appointment

    Senior Scientist

    Keywords

    Leishmaniasis
     Malaria
     Exosome
     Innate Inflammation
     Signaling
  8. Dr. Ciriaco Piccirillo

    Appointment

    Scientist

    Keywords

    Immunology
     T Cell Biology
     Autoimmune Diseases
     Inflammatory Diseases
  9. Dr. Danuta Radzioch

    Appointment

    Senior Scientist

    Keywords

    Inflammation
     Animal Models
     Translational Research
     Lipid Imbalance
     Gene Expression Regulation
  10. Dr. Joyce Rauch

    Appointment

    Senior Scientist

    Keywords

    Autoimmunity
     Systemic Lupus Erythematosus
     Autoantibodies
     T Cells
     Cell Death
  11. Dr. Michael Reed

    Appointment

    Scientist

    Keywords

    Tuberculosis (TB)
     Mycobacterium Tuberculosis
     Molecular Microbiology
     Bacterial Pathogenesis
  12. Dr. Jean-Pierre Routy

    Appointment

    Senior Scientist

    Keywords

    HIV
     Vaccine
     Lymphoma
     T Cells
     Cytokines
  13. Dr. Erwin Schurr

    Appointment

    Senior Scientist

    Keywords

    Tuberculosis
     Leprosy
     Complex Traits
     Transcriptomics
     Systems Biology
  14. Dr. Ernest Seidman

    Appointment

    Senior Scientist

    Keywords

    IBD
     Crohn's Disease
     Ulcerative Colitis
     Celiac Disease
     Translational Research
     Genetics
     Colon Cancer
     Autoimmune
     Intestinals
  15. Dr. Donald Sheppard

    Appointment

    Scientist

    Keywords

    Medical Mycology
     Aspergillus
     Biofilms
     Host‑pathogen Interactions
  16. Dr. Christos Tsoukas

    Appointment

    Senior Scientist

    Keywords

    Immune Risk Phenotype
     Inflammation
     Biomarkers
     Cardiovascular
     Immunopathology
     Cohort Studies
     T Cell Activation
     Primary Immune Deficiency
  17. Dr. Bernard Turcotte

    Appointment

    Scientist

    Keywords

    Pathogenic Fungi
     Transcription Factors
     Drug Resistance
     Genome‑wide Analysis
  18. Dr. Donald Vinh

    Appointment

    Scientist

    Keywords

    Primary (genetic) Immunodeficiencies
     Molecular Genetics
     Translational Research
     Immunity
     Infections
  19. Dr. Brian Ward

    Appointment

    Senior Scientist

    Keywords

    Vaccines
     Respiratory Viruses
     International Health
     Parasitology
     Diagnostics
  20. Dr. Cédric Yansouni

    Appointment

    Junior Scientist

    Keywords

    Diagnostics
     Parasitology
     Circumpolar Health
     Neglected Tropical Diseases
     Clinical Tropical Medicine

Centre of Outcomes Research and Evaluation (CORE)

Public TB hospital – photo by Dr. M. Pai
Public TB hospital – photo by Dr. M. Pai

Presently, the IDIGH Program has 20 CORE investigators.  The CORE members of our program carry out population and patient-oriented research, with focus on developing methodology, e.g. statical models to study various patient cohorts and global health problems. The CORE members will soon move to a building that is adjacent to the main MUHC campus. The close proximity of CORE members to CTB and Clinical Members of the IDIGH program does provide an important structural component for the generation of translational units that cover the spectrum of health care innovation.

The researchers of the CORE

  1. Dr. Moshe Ben-Shoshan

    Appointment

    Scientist

    Keywords

    Food Allergy
     Anaphylaxis
     Immunodeficiency
     Chronic Urticaria
  2. Dr. Sasha Bernatsky

    Appointment

    Scientist

    Keywords

    Epidemiology
     Systemic Lupus
     Rheumatic Disease
  3. Dr. Paul Brassard

    Appointment

    Scientist

    Keywords

    Epidemiology
     Public Health
     Aboriginal Health
     Cancer Prevention
     Infectious Diseases Control
  4. Dr. Marie-Josée Brouillette

    Appointment

    Scientist

    Keywords

    Cognition In HIV
     Depression
     Rasch Analysis
  5. Dr. Joseph Cox

    Appointment

    Investigator

    Keywords

    Public Health
     Preventive Medicine
     Epidemiology
     Quantitative Methods
     Addiction
     HIV
     HCV
     HIV‑HCV Co‑infection
     Men Who Have Sex With Men
     Injection Drug Use
     Prevention And Care Interventions
  6. Dr. Amrita Daftary

    Appointment

    Junior Scientist

    Keywords

    Tuberculosis
     Drug‑resistant TB
     HIV/AIDS
     Social Determinants Of Health
     Qualitative Methods
     Mixed Methods
     Implementation Science
     E‑health Interventions
  7. Dr. Alexandra De Pokomandy

    Appointment

    Scientist

    Keywords

    Human Papillomavirus
     HPV
     HIV
     Primary Care
  8. Dr. Nandini Dendukuri

    Appointment

    Scientist

    Keywords

    Bayesian Inference
     Biostatistics
     Diagnostic Tests
     Latents Class Models
     Technology Assessment
  9. Dr. Theresa Gyorkos

    Appointment

    Senior Scientist

    Keywords

    Global Health
     Parasite Epidemiology
     Neglected Tropical Diseases
  10. Dr. Lawrence Joseph

    Appointment

    Senior Scientist

    Keywords

    Bayesian Biostatistics
     Epidemiology
     Diagnostic Tests
     Research Design
  11. Dr. Marina Klein

    Appointment

    Senior Scientist

    Keywords

    HIV
     Hepatitis C
     Clinical Trials
     Epidemiology
     Antiretrovirals
     Prospective Cohort
  12. Dr. Bertrand Lebouché

    Appointment

    Junior Scientist

    Keywords

    HIV Care
     Biomedical HIV Prevention
     Patient‑reported Outcomes
     HIV Screening
     Men Who Have Sex With Men
  13. Dr. Todd Lee

    Appointment

    Scientist

    Keywords

    Quality Improvement
     Patient Safety
     High Value Healthcare
     Antibiotic Stewardship
     Polypharmacy
  14. Dr. Emily McDonald

    Appointment

    Junior Scientist

    Keywords

    Quality Improvement
     Patient Safety
     Infection
  15. Dr. Madhukar Pai

    Appointment

    Scientist

    Keywords

    Tuberculosis
     Diagnostics
     Epidemiology
     Global Health
     Implementation Research
  16. Dr. Nitika Pai

    Appointment

    Scientist

    Keywords

    HIV
     Rapid Point‑of‑care Tests
     Screening Strategies
     Innovative Applications
     Mhealth
     Global Health
     Womens Health
  17. Dr. Jesse Papenburg

    Appointment

    Junior Scientist

    Keywords

    Influenza
     Respiratory Syncytial Virus (RSV)
     Children
     Epidemiology
     Diagnosis
  18. Dr. Caroline Quach

    Appointment

    Scientist

    Keywords

    Vaccines
     Surveillance
     Healthcare‑associated Infections
     Public Health
     Epidemiology
  19. Dr. Giada Sebastiani

    Appointment

    Junior Scientist

    Keywords

    Fatty Liver
     Serum Fibrosis Biomarkers
     Hepatitis B
     Hepatitis C
     HIV
  20. Dr. Évelyne Vinet

    Appointment

    Junior Scientist

    Keywords

    Administrative Databases
     Clinical Epidemiology
     Health Outcomes
     Perinatal Outcomes
     Reproductive Health

Clinical

Currently, the IDIGH Clinical Research group consists of 19 investigators who conduct a broad range of clinical investigations, spanning Infectious Diseases, Clinical Immunology, Transplant and Gastroenterology.  Studies are conducted at a variety of sties of the MUHC, including the Glen campus, the MGH site and the Lachine campus.  A key focal point for clinical research is the newly developed Centre for Innovative Medicine that facilitates and streamlines outpatient clinical research in one state-of-the art facility.  Research conducted by IDIGH clinical investigators is highly collaborative on multiple levels, given the links with CTB researchers, CORE researchers and collaborators outside of the MUHC, both nationally and internationally.  A major strength of research by IDIGH investigators is the close vicinity of many clinical facilities to the CTB and the CORE, providing many opportunities for new research synergies. This interaction of research across the CIHR pillars positions IDIGH investigators for high-impact translational studies.

Clinical researchers

  1. Dr. Waqqas Afif

    Appointment

    Associate Investigator

    Keywords

    Inflammatory Bowel Disease
     Crohn's Disease
     Ulcerative Colitis
     Biologic Medications
     Therapeutic Drug Monitoring
  2. Dr. Talat Bessissow

    Appointment

    Associate Investigator

    Keywords

    Crohn's Disease
     Ulcerative Colitis
     Mucosal Healing
     Neoplasia
     Pathogenesis
  3. Dr. Alain Bitton

    Appointment

    Investigator

    Keywords

    Crohn's Disease
     Ulcerative Colitis
     Psychosocial
     Biologic Markers
     Genetics
  4. Dr. Marcelo Cantarovich

    Appointment

    Investigator

    Keywords

    Multi‑organ Transplant
  5. Dr. Julian Falutz

    Appointment

    Associate Investigator

    Keywords

    HIV
     Aging
     Metabolism
  6. Dr. Carolyn Jack

    Appointment

    Associate Investigator

    Keywords

    Dermatology
     Immunology
  7. Dr. Peter Lakatos

    Appointment

    Investigator

    Keywords

    Inflammatory Bowel Diseases (IBD)
     Gastroenterology
     Colitis
     Crohn’s Disease 
  8. Dr. Roger LeBlanc

    Appointment

    Associate Investigator

    Keywords

    HIV
     Drug Longterm Safety
  9. Dr. Michael Libman

    Appointment

    Investigator

    Keywords

    Tropical Diseases
     Parasitology
     Travel Medicine
     Epidemiology
  10. Dr. Vivian Loo

    Appointment

    Investigator

    Keywords

    Clostridium Difficile
     Healthcare‑associated Infections
     Infection Control
  11. Dr. Christian Pineau

    Appointment

    Investigator

    Keywords

    Lupus
     Morbidity
     Cardiovascular Disease
     Vasculitis
     Adherence To Treatment
     Prognostic Factors
  12. Dr. David Portnoy

    Appointment

    Associate Investigator

    Keywords

  13. Dr. Earl Rubin

    Appointment

    Investigator

    Keywords

    Vaccine Development
  14. Dr. Makeda Semret

    Appointment

    Investigator

    Keywords

    Hospital Infections
     Infection Control
     Molecular Diagnostics
     Antimicrobial Resistance
  15. Dr. Jean Tchervenkov

    Appointment

    Investigator

    Keywords

    Renal Transplantation
     Liver Transplantation
     Immunology
     Hepatitis B And C
     Xenotransplantation
  16. Dr. Philip Wong

    Appointment

    Associate Investigator

    Keywords

    Hepatology
     Hepatitis 
     Nonalcoholic Steatohepatitis

McGill University Campus-based

The IDIGH program presently has 5 McGill University campus-based researchers. Dr. Ken Dewar’s laboratory is located in the McGill University and Génome Québec Innovation Centre. His research focus is combining leading edge DNA sequencing technologies and bioinformatics to better understand genome structure and variation. Drs. Danielle Malo, Maya Saleh and Silvia Vidal are part of the McGill University’s Complex Traits Group, whose research focuses including employing mouse models and various genetic analysis tools to understand and elucidate pathogenesis and individual components of complex human diseases.

McGill University Campus-based researchers

  1. Dr. Ken Dewar

    Appointment

    Investigator

    Keywords

    Genomics
     Comparative Genomics
     DNA Sequence Analysis
  2. Dr. Danielle Malo

    Appointment

    Investigator

    Keywords

    Salmonella
     Typhoid
     Complex Disease
     Animal Model
     Mutagenesis
  3. Dr. Robert Nadon

    Appointment

    Investigator

    Keywords

    Microarrays
     Experimental Design
     Random Error Models
     Bias Correction
     Normalization
     Affymetrix Chips
     High‑throughput Screening
  4. Dr. Maya Saleh

    Appointment

    Investigator

    Keywords

    Innate Immunity
     Cell Death
     Infection
     Cancer
     Inflammatory Diseases
  5. Dr. Silvia Vidal

    Appointment

    Investigator

    Keywords

    Mouse Genetic Models
     Virus Infections
     Innate Immunity
     Complex Traits Analysis
     Primary Human Cells

IDIGH Calendar

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Upcoming Events

Latest IDIGH Publications

  1. Dubé, È., Farrands, A., Lemaitre, T., Boulianne, N., Sauvageau, C., Boucher, F. D., Tapiero, B., Quach, C., Ouakki, M., Gosselin, V., Gagnon, D., De Wals, P., Petit, G., Jacques, M.-C. & Gagneur, A.
    (2018)
    .
    Overview of knowledge, attitudes, beliefs, vaccine hesitancy and vaccine acceptance among mothers of infants in Quebec, Canada
    .
    Human vaccines & immunotherapeutics
  2. Ricciardi, A., Zelt, N. H., Visitsunthorn, K., Dalton, J. P. & Ndao, M.
    (2018)
    .
    Immune Mechanisms Involved in Schistosoma mansoni-Cathepsin B Vaccine Induced Protection in Mice
    .
    Frontiers in immunology
    ,
    vol
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    9
    ,
    p
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    1710
    .
  3. Shokoohi, M., Bauer, G. R., Kaida, A., Lacombe-Duncan, A., Kazemi, M., Gagnier, B., de Pokomandy, A., Loutfy, M. & CHIWOS Research Team.
    (2018)
    .
    Substance use patterns among women living with HIV compared with the general female population of Canada
    .
    Drug and alcohol dependence
    ,
    vol
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    191
    ,
    p
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    70-77
    .
  4. Salzer, H. J. F., Stoney, R. J., Angelo, K. M., Rolling, T., Grobusch, M. P., Libman, M., López-Vélez, R., Duvignaud, A., Ásgeirsson, H., Crespillo-Andújar, C., Schwartz, E., Gautret, P., Bottieau, E., Jordan, S., Lange, C., Hamer, D. H. & GeoSentinel Surveillance Network.
    (2018)
    .
    Epidemiological aspects of travel-related systemic endemic mycoses: a GeoSentinel analysis, 1997-2017
    .
    Journal of travel medicine
    ,
    vol
    .
    25
  5. Namazi, G., Fajnzylber, J. M., Aga, E., Bosch, R., Acosta, E. P., Sharaf, R., Hartogensis, W., Jacobson, J. M., Connick, E., Volberding, P., Skiest, D., Margolis, D., Sneller, M. C., Little, S. J., Gianella, S., Smith, D., Kuritzkes, D. R., Gulick, R. M., Mellors, J. W., Mehraj, V., Gandhi, R. T., Mitsuyasu, R., Schooley, R. T., Henry, K., Tebas, P., Deeks, S., Chun, T.-W., Collier, A. C., Routy, J.-P., Hecht, F. M., Walker, B. D. & Li, J. Z.
    (2018)
    .
    The Control of HIV after Antiretroviral Medication Pause (CHAMP) study: post-treatment controllers identified from 14 clinical studies
    .
    The Journal of infectious diseases
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